Literature DB >> 19941766

Intralesional corticosteroid injection for central giant cell granuloma: an alternative treatment for children.

Flavia Prietsh Wendt1, Marcos Antônio Torriani, Ana Paula Neutzling Gomes, Lenita Maria Aver de Araujo, Dione Dias Torriani.   

Abstract

The purpose of the present article was to report a case of central giant cell granuloma (CGCG) associated with intralesional corticosteroid injections. Although benign, the CGCG may be locally aggressive, causing extensive bone destruction, tooth displacement, and root resorption. The common therapy is surgery, which may result in important facial deformity and loss of teeth or dental germs. In this article, an 8-year-old girl who presented with maxillary CGCG was treated with a solution of equal parts of triamcinolone actinide (10 mg/ml) and 0.5% bupivacaine injected into the lesion for a period of 11 weeks. The osseous neoformation was gradual. After 6-years follow-up, clinical and radiographic success of treatment were observed. Based on our results and the literature available, the administration of intralesional corticosteroid injections is an alternative in CGCG treatment, especially in children.

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Year:  2009        PMID: 19941766

Source DB:  PubMed          Journal:  J Dent Child (Chic)        ISSN: 1551-8949


  4 in total

1.  Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature.

Authors:  Doğan Dolanmaz; Alparslan Esen; Ahmet Mihmanlı; Kubilay Işık
Journal:  Oral Maxillofac Surg       Date:  2015-10-19

2.  Giant Cell Granuloma: Two Expressions in Pediatric Population.

Authors:  Chitrita G Mukherjee; Uday Mukherjee; Anju Bansal; Madhushree Mukhopadhyay
Journal:  Int J Clin Pediatr Dent       Date:  2017-02-01

3.  Intra-Lesional Medicaments for the Management of Intra-Osseous Lesions of Maxilla and Mandible - Systematic Review.

Authors:  Komal Smriti; Evit John; Kalyana-Chakravarthy Pentapati; Srikanth Gadicherla; Manish Bhagania
Journal:  J Int Soc Prev Community Dent       Date:  2020-01-24

4.  Intralesional corticosteroid injections in the treatment of central giant cell lesions of the jaws: a meta-analytic study.

Authors:  Rafael-Lima-Verde Osterne; Phelype-Maia Araújo; Abrahao-Cavalcante-Gomes de Souza-Carvalho; Roberta-Barroso Cavalcante; Eduardo Sant'Ana; Renato-Luiz-Maia Nongueira
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2013-03-01
  4 in total

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