Literature DB >> 26479278

Pharmacoepidemiologic Methods for Studying the Health Effects of Drug-Drug Interactions.

S Hennessy1, C E Leonard1, J J Gagne2, J H Flory1,3,4, X Han1, C M Brensinger1, W B Bilker1.   

Abstract

A drug-drug interaction (DDI) occurs when one or more drugs affect the pharmacokinetics (the body's effect on the drug) and/or pharmacodynamics (the drug's effect on the body) of one or more other drugs. Pharmacoepidemiologic studies are the principal way of studying the health effects of potential DDIs. This article discusses aspects of pharmacoepidemiologic research designs that are particularly salient to the design and interpretation of pharmacoepidemiologic studies of DDIs.
© 2015 American Society for Clinical Pharmacology and Therapeutics.

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Year:  2015        PMID: 26479278      PMCID: PMC4720556          DOI: 10.1002/cpt.277

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


  28 in total

1.  Marginal structural models and causal inference in epidemiology.

Authors:  J M Robins; M A Hernán; B Brumback
Journal:  Epidemiology       Date:  2000-09       Impact factor: 4.822

Review 2.  Hospitalisations and emergency department visits due to drug-drug interactions: a literature review.

Authors:  Matthijs L Becker; Marjon Kallewaard; Peter W J Caspers; Loes E Visser; Hubert G M Leufkens; Bruno H Ch Stricker
Journal:  Pharmacoepidemiol Drug Saf       Date:  2007-06       Impact factor: 2.890

3.  Immortal time bias in observational studies of drug effects.

Authors:  Samy Suissa
Journal:  Pharmacoepidemiol Drug Saf       Date:  2007-03       Impact factor: 2.890

Review 4.  Mechanisms of drug combinations: interaction and network perspectives.

Authors:  Jia Jia; Feng Zhu; Xiaohua Ma; Zhiwei Cao; Zhiwei W Cao; Yixue Li; Yixue X Li; Yu Zong Chen
Journal:  Nat Rev Drug Discov       Date:  2009-02       Impact factor: 84.694

5.  Drug-drug interactions among elderly patients hospitalized for drug toxicity.

Authors:  David N Juurlink; Muhammad Mamdani; Alexander Kopp; Andreas Laupacis; Donald A Redelmeier
Journal:  JAMA       Date:  2003-04-02       Impact factor: 56.272

6.  Incidence and preventability of adverse drug events among older persons in the ambulatory setting.

Authors:  Jerry H Gurwitz; Terry S Field; Leslie R Harrold; Jeffrey Rothschild; Kristin Debellis; Andrew C Seger; Cynthia Cadoret; Leslie S Fish; Lawrence Garber; Michael Kelleher; David W Bates
Journal:  JAMA       Date:  2003-03-05       Impact factor: 56.272

7.  Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine.

Authors:  Vered Stearns; Michael D Johnson; James M Rae; Alan Morocho; Antonella Novielli; Pankaj Bhargava; Daniel F Hayes; Zeruesenay Desta; David A Flockhart
Journal:  J Natl Cancer Inst       Date:  2003-12-03       Impact factor: 13.506

8.  Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal bleeding.

Authors:  H Schelleman; W B Bilker; C M Brensinger; X Han; S E Kimmel; S Hennessy
Journal:  Clin Pharmacol Ther       Date:  2008-08-06       Impact factor: 6.875

Review 9.  Understanding and preventing drug interactions in elderly patients.

Authors:  Jeffrey C Delafuente
Journal:  Crit Rev Oncol Hematol       Date:  2003-11       Impact factor: 6.312

10.  Evaluating medication effects outside of clinical trials: new-user designs.

Authors:  Wayne A Ray
Journal:  Am J Epidemiol       Date:  2003-11-01       Impact factor: 4.897

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  34 in total

1.  Serious Hypoglycemia and Use of Warfarin in Combination With Sulfonylureas or Metformin.

Authors:  Young Hee Nam; Colleen M Brensinger; Warren B Bilker; Charles E Leonard; Xu Han; Sean Hennessy
Journal:  Clin Pharmacol Ther       Date:  2018-08-06       Impact factor: 6.875

2.  Generating Evidence of Clinical Outcomes of Drug-Drug Interactions.

Authors:  Katsiaryna Bykov; Joshua J Gagne
Journal:  Drug Saf       Date:  2017-02       Impact factor: 5.606

Review 3.  A comprehensive review and meta-analysis of risk factors for statin-induced myopathy.

Authors:  Khoa A Nguyen; Lang Li; Deshun Lu; Aida Yazdanparast; Lei Wang; Rolf P Kreutz; Elizabeth C Whipple; Titus K Schleyer
Journal:  Eur J Clin Pharmacol       Date:  2018-05-22       Impact factor: 2.953

4.  Clopidogrel Drug Interactions and Serious Bleeding: Generating Real-World Evidence via Automated High-Throughput Pharmacoepidemiologic Screening.

Authors:  Charles E Leonard; Meijia Zhou; Colleen M Brensinger; Warren B Bilker; Samantha E Soprano; Thanh Phuong Pham Nguyen; Young Hee Nam; Jordana B Cohen; Sean Hennessy
Journal:  Clin Pharmacol Ther       Date:  2019-07-04       Impact factor: 6.875

5.  Pharmacoepidemiologic Screening of Potential Oral Anticoagulant Drug Interactions Leading to Thromboembolic Events.

Authors:  Meijia Zhou; Charles E Leonard; Colleen M Brensinger; Warren B Bilker; Stephen E Kimmel; Todd E H Hecht; Sean Hennessy
Journal:  Clin Pharmacol Ther       Date:  2020-05-16       Impact factor: 6.875

6.  Mixture drug-count response model for the high-dimensional drug combinatory effect on myopathy.

Authors:  Xueying Wang; Pengyue Zhang; Chien-Wei Chiang; Hengyi Wu; Li Shen; Xia Ning; Donglin Zeng; Lei Wang; Sara K Quinney; Weixing Feng; Lang Li
Journal:  Stat Med       Date:  2017-11-23       Impact factor: 2.373

7.  The Self-Controlled Case Series Design as a Viable Alternative to Studying Clinically Relevant Drug Interactions.

Authors:  Meijia Zhou; Charles E Leonard; Warren B Bilker; Sean Hennessy
Journal:  Clin Pharmacol Ther       Date:  2019-10-21       Impact factor: 6.875

8.  Gastrointestinal bleeding and intracranial hemorrhage in concomitant users of warfarin and antihyperlipidemics.

Authors:  Charles E Leonard; Colleen M Brensinger; Warren B Bilker; Stephen E Kimmel; Xu Han; Young Hee Nam; Joshua J Gagne; Margaret J Mangaali; Sean Hennessy
Journal:  Int J Cardiol       Date:  2016-11-12       Impact factor: 4.164

9.  Screening to identify signals of opioid drug interactions leading to unintentional traumatic injury.

Authors:  Charles E Leonard; Colleen M Brensinger; Thanh Phuong Pham Nguyen; John R Horn; Sophie Chung; Warren B Bilker; Sascha Dublin; Samantha E Soprano; Ghadeer K Dawwas; David W Oslin; Douglas J Wiebe; Sean Hennessy
Journal:  Biomed Pharmacother       Date:  2020-07-30       Impact factor: 6.529

10.  Drug-physiology interaction and its influence on the QT prolongation-mechanistic modeling study.

Authors:  Barbara Wiśniowska; Sebastian Polak
Journal:  J Pharmacokinet Pharmacodyn       Date:  2018-03-15       Impact factor: 2.745

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