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Literature DB >> 26474085

Morpholino-driven gene editing: A new horizon for disease treatment and prevention.

E Subbotina¹, S R K Koganti¹, D M Hodgson-Zingman^1,2,3, L V Zingman^1,2,3,4.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Drug Carriers
Morpholinos

Year: 2015 PMID： 26474085 PMCID： PMC4720544 DOI： 10.1002/cpt.276

Source DB: PubMed Journal: Clin Pharmacol Ther ISSN： 0009-9236 Impact factor: 6.875

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5 in total

1. Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis.

Authors: Siva Rama Krishna Koganti; Zhiyong Zhu; Ekaterina Subbotina; Zhan Gao; Ana Sierra; Manuel Proenza; Liping Yang; Alexey Alekseev; Denice Hodgson-Zingman; Leonid Zingman
Journal: Mol Ther Date: 2015-02-04 Impact factor: 11.454

Review 2. In vivo delivery of morpholino oligos by cell-penetrating peptides.

Authors: Hong M Moulton
Journal: Curr Pharm Des Date: 2013 Impact factor: 3.116

Review 3. Exon skipping therapy for Duchenne muscular dystrophy.

Authors: Ryszard Kole; Arthur M Krieg
Journal: Adv Drug Deliv Rev Date: 2015-05-14 Impact factor: 15.470

4. Uncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages.

Authors: E P Stirchak; J E Summerton; D D Weller
Journal: Nucleic Acids Res Date: 1989-08-11 Impact factor: 16.971

Review 5. Gene knockdowns in adult animals: PPMOs and vivo-morpholinos.

Authors: Jon D Moulton; Shan Jiang
Journal: Molecules Date: 2009-03-25 Impact factor: 4.411

5 in total

6 in total

1. Clinical Pharmacology & Therapeutics: Past, Present, and Future.

Authors: S A Waldman; A Terzic
Journal: Clin Pharmacol Ther Date: 2017-03 Impact factor: 6.875

2. Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors.

Authors: P Ambady; Y J Wu; J M Walker; C Kersch; M A Pagel; R L Woltjer; R Fu; L L Muldoon; E A Neuwelt
Journal: Cancer Gene Ther Date: 2017-07-28 Impact factor: 5.987

Morpholino-driven gene editing: A new horizon for disease treatment and prevention.

1. Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis.

Review 2. In vivo delivery of morpholino oligos by cell-penetrating peptides.

Review 3. Exon skipping therapy for Duchenne muscular dystrophy.

4. Uncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages.

Review 5. Gene knockdowns in adult animals: PPMOs and vivo-morpholinos.

1. Clinical Pharmacology & Therapeutics: Past, Present, and Future.

2. Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors.

Review 3. Aberrant Bcl-x splicing in cancer: from molecular mechanism to therapeutic modulation.

Review 4. Advanced In vivo Use of CRISPR/Cas9 and Anti-sense DNA Inhibition for Gene Manipulation in the Brain.

Review 5. Controlling Mast Cell Activation and Homeostasis: Work Influenced by Bill Paul That Continues Today.

6. TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNα production.