Lichun Feng1, Aiyan Jin1, Baoqiang Dai1, Yanping Li1, Yusheng Guo2, Daowen Wang3, Peng Xu1. 1. a Department of Otolaryngology , Cangzhou Central Hospital , Cangzhou , Hebei Province , PR China. 2. b Department of Otolaryngology , People's Hospital of Yanshan County , Cangzhou , PR China. 3. c Department of Otolaryngology, Head and Neck Surgery , Peking University Health Science Center , Beijing , PR China.
Abstract
CONCLUSIONS: Early diagnosis and treatment were critical to prevent recurrence, and the long-term outcomes were satisfactory after surgery and post-operative radiotherapy. OBJECTIVES: To present outcomes of 18 cases with squamous cell carcinoma of the middle ear who underwent both surgery and post-operative radiotherapy. METHODS: Eighteen cases with squamous cell carcinoma of the middle ear (two cases of T1, five of T2, and 11 of T3) underwent surgery and post-operative radiotherapy, and a surgical approach was determined by tumour sites. Extended mastoidotympanectomy was performed on two cases, with subtotal temporal bone resection on 12 cases and temporal bone resection on four cases. The patients who had cervical metastasis underwent additional radical neck resection and post-operative radiotherapy at the neck. The patients were followed-up after surgery. RESULTS: During the follow-up, no cases of T1 recurred, and six cases of T2 or T3 recurred, with the total recurrence rate of 37.5% among the patients of T2 and T3. At the fifth year after surgery, 15 patients were still alive, and the actual 5-year survival rate was 83.3% among all patients.
CONCLUSIONS: Early diagnosis and treatment were critical to prevent recurrence, and the long-term outcomes were satisfactory after surgery and post-operative radiotherapy. OBJECTIVES: To present outcomes of 18 cases with squamous cell carcinoma of the middle ear who underwent both surgery and post-operative radiotherapy. METHODS: Eighteen cases with squamous cell carcinoma of the middle ear (two cases of T1, five of T2, and 11 of T3) underwent surgery and post-operative radiotherapy, and a surgical approach was determined by tumour sites. Extended mastoidotympanectomy was performed on two cases, with subtotal temporal bone resection on 12 cases and temporal bone resection on four cases. The patients who had cervical metastasis underwent additional radical neck resection and post-operative radiotherapy at the neck. The patients were followed-up after surgery. RESULTS: During the follow-up, no cases of T1 recurred, and six cases of T2 or T3 recurred, with the total recurrence rate of 37.5% among the patients of T2 and T3. At the fifth year after surgery, 15 patients were still alive, and the actual 5-year survival rate was 83.3% among all patients.
Entities:
Keywords:
Squamous cell carcinoma; middle ear; radiotherapy; temporal bone resection
Authors: Cindy H Nabuurs; Wietske Kievit; Nilou Labbé; C René Leemans; Conrad F G M Smit; Michiel W M van den Brekel; Robert J Pauw; Bernard F A M van der Laan; Jeroen C Jansen; Martin Lacko; Weibel W Braunius; Shinya Morita; Małgorzata Wierzbicka; Takuma Matoba; Nobuhiro Hanai; Robert P Takes; Henricus P M Kunst Journal: Head Neck Date: 2020-08-13 Impact factor: 3.147