Literature DB >> 26470613

Hidradenitis suppurativa in the pediatric population.

Carmen Liy-Wong1, Elena Pope1, Irene Lara-Corrales2.   

Abstract

Hidradenitis suppurativa (HS) generally appears after puberty, is infrequently seen in younger children, and early onset, which is associated with more widespread disease, is more common in children with a positive family history of HS. When compared with adults with HS, children with HS are more likely to have hormonal imbalances, making hormonal investigations integral to disease management in pediatric patients. HS affects intertriginous areas, presenting with double-ended comedones, tender subcutaneous nodules, purulent discharge, and the formation of sinus tracts, hypertrophic fibrotic scars, and dermal contractures. Treatment of HS in children has not been well studied. The goals of therapy in the pediatric setting are to alleviate pain, minimize inflammation and scarring, prevent disease progression, and postpone the need for surgery. Mild cases can be treated with topical antibiotics, while topical and oral antibiotics are the primary therapies for moderate forms of HS. Modalities like biologic agents, laser therapy, or surgery have been reserved for severe pediatric cases of HS. Early recognition and treatment are critical to minimize the effects of the disease on the life course. Given the significant impact of the condition on quality of life and self-esteem, there is a clear role for psychological support.
Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  childhood hidradenitis; early onset hidradenitis suppurativa; hidradenitis in children; hidradenitis suppurativa in pediatric population

Mesh:

Substances:

Year:  2015        PMID: 26470613     DOI: 10.1016/j.jaad.2015.07.051

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  8 in total

1.  Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients.

Authors:  Peter Theut Riis; Ditte Marie Saunte; Viktoria Sigsgaard; Axel Patrice Villani; Philippe Guillem; José C Pascual; Naomi N Kappe; Annika M J D Vanlaerhoven; Hessel H van der Zee; Errol P Prens; Moetaz El-Domyati; Hossam Abdel-Wahab; Nayera Moftah; Rania Abdelghani; Eugenia Agut-Busquet; Jorge Romaní; Carol Hlela; Lerinza van den Worm; Vincenzo Bettoli; Giada Calamo; Mehmet Ali Gürer; Burcu Beksaç; Lukasz Matusiak; Amelia Glowaczewska; Jacek C Szepietowski; Lennart Emtestam; Jan Lapins; Hassan Riad Kottb; Mohammad Fatani; Lisa Weibel; Martin Theiler; Maïa Delage-Toriel; Thi Thanh Hong Lam; Aude Nassif; Pierre-Andre Becherel; Mateja Dolenc-Voljc; Nejib Doss; Dorra Bouazzi; Farida Benhadou; Veronique Del Marmol; Gregor B E Jemec
Journal:  Arch Dermatol Res       Date:  2020-03-12       Impact factor: 3.017

2.  Proceeding report of the third symposium on Hidradenitis Suppurativa advances (SHSA) 2018.

Authors:  Claudia J Posso-De Los Rios; Akua Sarfo; Mondana Ghias; Raed Alhusayen; Iltefat Hamzavi; Michelle A Lowes; Afsaneh Alavi
Journal:  Exp Dermatol       Date:  2019-04-29       Impact factor: 3.960

3.  Model-Informed Drug Development Approach Supporting Approval of Adalimumab (HUMIRA) in Adolescent Patients with Hidradenitis Suppurativa: a Regulatory Perspective.

Authors:  Youwei Bi; Jiang Liu; Jie Wang; Roselyn E Epps; David Kettl; Kendall Marcus; Shirley Seo; Hao Zhu; Yaning Wang
Journal:  AAPS J       Date:  2019-07-19       Impact factor: 4.009

Review 4.  North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management.

Authors:  Ali Alikhan; Christopher Sayed; Afsaneh Alavi; Raed Alhusayen; Alain Brassard; Craig Burkhart; Karen Crowell; Daniel B Eisen; Alice B Gottlieb; Iltefat Hamzavi; Paul G Hazen; Tara Jaleel; Alexa B Kimball; Joslyn Kirby; Michelle A Lowes; Robert Micheletti; Angela Miller; Haley B Naik; Dennis Orgill; Yves Poulin
Journal:  J Am Acad Dermatol       Date:  2019-03-11       Impact factor: 15.487

5.  Disseminate Recurrent Folliculitis and Hidradenitis Suppurativa Are Associated Conditions: Results From a Retrospective Study of 131 Patients With Down Syndrome and a Cohort of 12,351 Pediatric Controls.

Authors:  Andrea Sechi; Alba Guglielmo; Annalisa Patrizi; Francesco Savoia; Guido Cocchi; Miriam Leuzzi; Marco A Chessa
Journal:  Dermatol Pract Concept       Date:  2019-07-31

Review 6.  The impact of pediatric skin disease on self-esteem.

Authors:  K L Vivar; L Kruse
Journal:  Int J Womens Dermatol       Date:  2017-12-12

Review 7.  Pleiotropic Role of Notch Signaling in Human Skin Diseases.

Authors:  Rossella Gratton; Paola Maura Tricarico; Chiara Moltrasio; Ana Sofia Lima Estevão de Oliveira; Lucas Brandão; Angelo Valerio Marzano; Luisa Zupin; Sergio Crovella
Journal:  Int J Mol Sci       Date:  2020-06-13       Impact factor: 5.923

8.  Biologic Use in Pediatric Patients With Hidradenitis Suppurativa: A Systematic Review.

Authors:  Muskaan Sachdeva; Patrick Kim; Asfandyar Mufti; Khalad Maliyar; Cathryn Sibbald; Afsaneh Alavi
Journal:  J Cutan Med Surg       Date:  2021-09-29       Impact factor: 2.092

  8 in total

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