Literature DB >> 26466826

Achieving the World Health Organization's vision for clinical pharmacology.

Jennifer H Martin1,2, David Henry3, Jean Gray4, Richard Day5, Felix Bochner6, Albert Ferro7, Munir Pirmohamed8, Klaus Mörike2, Matthias Schwab2,9.   

Abstract

Clinical pharmacology is a medical specialty whose practitioners teach, undertake research, frame policy, give information and advice about the actions and proper uses of medicines in humans and implement that knowledge in clinical practice. It involves a combination of several activities: drug discovery and development, training safe prescribers, providing objective and evidence-based therapeutic information to ethics, regulatory and pricing bodies, supporting patient care in an increasingly subspecialized arena where co-morbidities, polypharmacy, altered pharmacokinetics and drug interactions are common and developing and contributing to medicines policies for Governments. Clinical pharmacologists must advocate drug quality and they must also advocate for sustainability of the Discipline. However for this they need appropriate clinical service and training support. This Commentary discusses strategies to ensure the Discipline is supported by teaching, training and policy organizations, to communicate the full benefits of clinical pharmacology services, put a monetary value on clinical pharmacology services and to grow the clinical pharmacology workforce to support a growing clinical, academic and regulatory need.
© 2015 The British Pharmacological Society.

Entities:  

Keywords:  clinical pharmacology; health workforce; leadership

Mesh:

Year:  2015        PMID: 26466826      PMCID: PMC4833156          DOI: 10.1111/bcp.12803

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  12 in total

1.  A manifesto for clinical pharmacology from principles to practice.

Authors:  Jeffrey K Aronson
Journal:  Br J Clin Pharmacol       Date:  2010-07       Impact factor: 4.335

2.  Adding the 'medicines' back into personalized medicine to improve cancer treatment outcomes.

Authors:  Jennifer H Martin; Elizabeth Phillips; David Thomas; Andrew A Somogyi
Journal:  Br J Clin Pharmacol       Date:  2015-11       Impact factor: 4.335

3.  Clinical Pharmacology in European health care-outcome of a questionnaire study in 31 countries.

Authors:  Michael Orme; Folke Sjöqvist
Journal:  Eur J Clin Pharmacol       Date:  2013-05-10       Impact factor: 2.953

4.  Strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in mainland Han Chinese patients.

Authors:  Yan Zhang; Jin Wang; Li-Mei Zhao; Wei Peng; Guo-Qing Shen; Ling Xue; Xiao-Xian Zheng; Xiao-Jing He; Chun-Yan Gong; Li-Yan Miao
Journal:  Eur J Clin Pharmacol       Date:  2011-03-19       Impact factor: 2.953

Review 5.  Genetic polymorphism and toxicology--with emphasis on cytochrome p450.

Authors:  Inger Johansson; Magnus Ingelman-Sundberg
Journal:  Toxicol Sci       Date:  2010-12-13       Impact factor: 4.849

6.  Why do interns make prescribing errors? A qualitative study.

Authors:  Ian D Coombes; Danielle A Stowasser; Judith A Coombes; Charles Mitchell
Journal:  Med J Aust       Date:  2008-01-21       Impact factor: 7.738

7.  HLA-B*5701 screening for hypersensitivity to abacavir.

Authors:  Simon Mallal; Elizabeth Phillips; Giampiero Carosi; Jean-Michel Molina; Cassy Workman; Janez Tomazic; Eva Jägel-Guedes; Sorin Rugina; Oleg Kozyrev; Juan Flores Cid; Phillip Hay; David Nolan; Sara Hughes; Arlene Hughes; Susanna Ryan; Nicholas Fitch; Daren Thorborn; Alastair Benbow
Journal:  N Engl J Med       Date:  2008-02-07       Impact factor: 91.245

Review 8.  Achieving the World Health Organization's vision for clinical pharmacology.

Authors:  Jennifer H Martin; David Henry; Jean Gray; Richard Day; Felix Bochner; Albert Ferro; Munir Pirmohamed; Klaus Mörike; Matthias Schwab
Journal:  Br J Clin Pharmacol       Date:  2015-11-23       Impact factor: 4.335

Review 9.  Personalized pharmacogenomics: predicting efficacy and adverse drug reactions.

Authors:  Munir Pirmohamed
Journal:  Annu Rev Genomics Hum Genet       Date:  2014-05-29       Impact factor: 8.929

10.  Choosing Wisely in the UK: the Academy of Medical Royal Colleges' initiative to reduce the harms of too much medicine.

Authors:  A Malhotra; D Maughan; J Ansell; R Lehman; A Henderson; M Gray; T Stephenson; S Bailey
Journal:  BMJ       Date:  2015-05-12
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  7 in total

1.  Reconsidering clinical pharmacology frameworks as a necessary strategy for improving the health care of patients: a systematic review.

Authors:  Davide Grisafi; Alessandro Ceschi; Gianni Sava; Veronica Avalos Clerici; Francesco Scaglione
Journal:  Eur J Clin Pharmacol       Date:  2018-07-14       Impact factor: 2.953

Review 2.  Achieving the World Health Organization's vision for clinical pharmacology.

Authors:  Jennifer H Martin; David Henry; Jean Gray; Richard Day; Felix Bochner; Albert Ferro; Munir Pirmohamed; Klaus Mörike; Matthias Schwab
Journal:  Br J Clin Pharmacol       Date:  2015-11-23       Impact factor: 4.335

3.  Modelling Medications for Public Health Research.

Authors:  D van Gaans; S Ahmed; K D'Onise; J Moyon; G Caughey; R McDermott
Journal:  Online J Public Health Inform       Date:  2016-09-15

4.  Parasitic pharmacology: A plausible mechanism of action for cannabidiol.

Authors:  Geert Jan Groeneveld; Jennifer H Martin
Journal:  Br J Clin Pharmacol       Date:  2019-07-10       Impact factor: 4.335

Review 5.  Nursing Personnel in the Era of Personalized Healthcare in Clinical Practice.

Authors:  Marios Spanakis; Athina E Patelarou; Evridiki Patelarou
Journal:  J Pers Med       Date:  2020-06-29

6.  European association for clinical pharmacology and therapeutics young clinical pharmacologists working group: a cornerstone for the brighter future of clinical pharmacology.

Authors:  Andrej Belančić; Carla Sans-Pola; Emilie Jouanjus; Pau Alcubilla; Ana Lucía Arellano; Miodrag Žunić; Rita Nogueiras-Álvarez; Rossana Roncato; Joaquín Sáez-Peñataro
Journal:  Eur J Clin Pharmacol       Date:  2022-01-17       Impact factor: 2.953

7.  From genomic medicine to precision medicine: highlights of 2015.

Authors:  Charles Auffray; Timothy Caulfield; Julian L Griffin; Muin J Khoury; James R Lupski; Matthias Schwab
Journal:  Genome Med       Date:  2016-01-29       Impact factor: 11.117

  7 in total

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