Literature DB >> 2646141

Inhibition of interleukin-1 beta release from cultured human peripheral blood mononuclear cells by prednisolone.

A Uehara1, H Kohda, C Sekiya, Y Takasugi, M Namiki.   

Abstract

Prednisolone, a water-soluble glucocorticoid hormone, suppressed the secretion of interleukin-1 beta from human peripheral blood mononuclear cells in culture. The prednisolone-induced suppression of the monokine release was dose-related and the half maximal response was observed at 0.1 nM.

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Year:  1989        PMID： 2646141     DOI： 10.1007/bf01954861

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  Changes in blood hormone levels during the immune response.

Authors:  H Besedovsky; E Sorkin; M Keller; J Müller
Journal:  Proc Soc Exp Biol Med       Date:  1975-11

2.  Interleukin-1 stimulates ACTH release by an indirect action which requires endogenous corticotropin releasing factor.

Authors:  A Uehara; P E Gottschall; R R Dahl; A Arimura
Journal:  Endocrinology       Date:  1987-10       Impact factor: 4.736

3.  Effects of interleukin-1 on hormone release from normal rat pituitary cells in primary culture.

Authors:  A Uehara; S Gillis; A Arimura
Journal:  Neuroendocrinology       Date:  1987-05       Impact factor: 4.914

4.  Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1.

Authors:  F Berkenbosch; J van Oers; A del Rey; F Tilders; H Besedovsky
Journal:  Science       Date:  1987-10-23       Impact factor: 47.728

Review 5.  Regulation of the immune system by sex steroids.

Authors:  C J Grossman
Journal:  Endocr Rev       Date:  1984       Impact factor: 19.871

6.  Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production.

Authors:  D S Snyder; E R Unanue
Journal:  J Immunol       Date:  1982-11       Impact factor: 5.422

7.  Stimulation of ACTH release by human interleukin-1 beta, but not by interleukin-1 alpha, in conscious, freely-moving rats.

Authors:  A Uehara; P E Gottschall; R R Dahl; A Arimura
Journal:  Biochem Biophys Res Commun       Date:  1987-08-14       Impact factor: 3.575

8.  Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs.

Authors:  C J March; B Mosley; A Larsen; D P Cerretti; G Braedt; V Price; S Gillis; C S Henney; S R Kronheim; K Grabstein
Journal:  Nature       Date:  1985 Jun 20-26       Impact factor: 49.962

9.  Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones.

Authors:  H Besedovsky; A del Rey; E Sorkin; C A Dinarello
Journal:  Science       Date:  1986-08-08       Impact factor: 47.728

10.  Functional analysis of mononuclear cells infiltrating into tumors. II. Differential ability of mononuclear cells obtained from various tissues to produce helper factors that are involved in the generation of cytotoxic cells.

Authors:  T Uede; H Kohda; Y Ibayashi; H Osawa; T Diamantstein; K Kikuchi
Journal:  J Immunol       Date:  1985-11       Impact factor: 5.422
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  3 in total

1.  Effects on interleukin 1 alpha and beta production of peripheral blood mononuclear cells from patients with hepatocellular carcinoma after transcatheter arterial embolization.

Authors:  M Kanai; H Kohda; C Sekiya; M Namiki
Journal:  Gastroenterol Jpn       Date:  1990-10

2.  Febrile responses induced in adrenalectomized rats by administration of interleukin-1 beta or prostaglandin E2.

Authors:  T Watanabe; T Makisumi; M Macari; N Tan; T Nakamori; S Nakamura; N Murakami
Journal:  J Physiol       Date:  1995-05-01       Impact factor: 5.182

3.  Lack of involvement of lipocortin 1 in dexamethasone suppression of IL-1 release.

Authors:  E F Morand; D Rickard; N J Goulding
Journal:  Mediators Inflamm       Date:  1993       Impact factor: 4.711
  3 in total

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