Yoo-Been Ahn1, Myung-Seop Shin1, Jong-Seok Byun2, Hyun-Duck Kim1,3. 1. Department of Preventive and Social Dentistry, School of Dentistry, Seoul National University, Seoul, Korea. 2. Department of Applied Statistics, College of IT, Hanshin University, Osan-Si, Gyeonggi-Do, Korea. 3. Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
Abstract
AIM: To evaluate the association of hypertension and high systolic and diastolic blood pressure (SBP and DBP) with periodontitis in a nationally representative Korean adult population. MATERIALS AND METHODS: Total of 14,625 participants of Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) aged over 19 years were cross-sectionally surveyed. Periodontitis was defined as CPI score of 3 or 4. Hypertension was categorized as: normotensive (SBP < 120 mmHg and DBP < 80 mmHg), pre-hypertensive (120 < SBP < 140 mmHg or 80 < DBP < 90 mmHg) and hypertensive (SBP ≥ 140 mmHg or DBP ≥ 90 mmHg or taking antihypertensive medication). Multivariate Poisson regression analyses were performed controlling for age, sex, household income, drinking, smoking, physical activity, obesity, hypercholesterolaemia and diabetes mellitus. Stratified analyses were performed to identify specific risk groups. RESULTS: Hypertension showed a significant positive association with periodontitis in the fully adjusted model in female adults with a dose-response relationship. This association was highlighted in females aged 30-59 years (prevalence ratio = 1.25; 95% confidence interval: 1.11-1.40). The strength of the association was highest in females aged 30-39 years and decreased with increasing age. Among females aged 30-59 years, high-risk groups of this link were lower middle income quartile, never drinker and non-diabetes groups for both pre-hypertension and hypertension. CONCLUSION: Our data showed that hypertension was associated with periodontitis in Korean female adults independent of known confounders.
AIM: To evaluate the association of hypertension and high systolic and diastolic blood pressure (SBP and DBP) with periodontitis in a nationally representative Korean adult population. MATERIALS AND METHODS: Total of 14,625 participants of Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) aged over 19 years were cross-sectionally surveyed. Periodontitis was defined as CPI score of 3 or 4. Hypertension was categorized as: normotensive (SBP < 120 mmHg and DBP < 80 mmHg), pre-hypertensive (120 < SBP < 140 mmHg or 80 < DBP < 90 mmHg) and hypertensive (SBP ≥ 140 mmHg or DBP ≥ 90 mmHg or taking antihypertensive medication). Multivariate Poisson regression analyses were performed controlling for age, sex, household income, drinking, smoking, physical activity, obesity, hypercholesterolaemia and diabetes mellitus. Stratified analyses were performed to identify specific risk groups. RESULTS:Hypertension showed a significant positive association with periodontitis in the fully adjusted model in female adults with a dose-response relationship. This association was highlighted in females aged 30-59 years (prevalence ratio = 1.25; 95% confidence interval: 1.11-1.40). The strength of the association was highest in females aged 30-39 years and decreased with increasing age. Among females aged 30-59 years, high-risk groups of this link were lower middle income quartile, never drinker and non-diabetes groups for both pre-hypertension and hypertension. CONCLUSION: Our data showed that hypertension was associated with periodontitis in Korean female adults independent of known confounders.
Authors: Marta Czesnikiewicz-Guzik; Ryszard Nosalski; Tomasz P Mikolajczyk; Francesca Vidler; Tomasz Dohnal; Elzbieta Dembowska; Delyth Graham; David G Harrison; Tomasz J Guzik Journal: Br J Pharmacol Date: 2018-12-26 Impact factor: 8.739
Authors: Najla Dar-Odeh; Sary Borzangy; Hamzah Babkair; Lamis Farghal; Ghufran Shahin; Sawsan Fadhlalmawla; Walaa Alhazmi; Sarah Taher; Osama Abu-Hammad Journal: Int J Environ Res Public Health Date: 2019-07-18 Impact factor: 3.390