Literature DB >> 26457320

Open source and DIY hardware for DNA nanotechnology labs.

Tulsi R Damase1, Daniel Stephens1, Adam Spencer1, Peter B Allen1.   

Abstract

A set of instruments and specialized equipment is necessary to equip a laboratory to work with DNA. Reducing the barrier to entry for DNA manipulation should enable and encourage new labs to enter the field. We present three examples of open source/DIY technology with significantly reduced costs relative to commercial equipment. This includes a gel scanner, a horizontal PAGE gel mold, and a homogenizer for generating DNA-coated particles. The overall cost savings obtained by using open source/DIY equipment was between 50 and 90%.

Entities:  

Keywords:  DNA; DNA nanotechnology; open source; open source scientific hardware

Year:  2015        PMID： 26457320      PMCID： PMC4598940          DOI： 10.14440/jbm.2015.72

Source DB:  PubMed          Journal:  J Biol Methods        ISSN： 2326-9901


  23 in total

1.  Programming biomolecular self-assembly pathways.

Authors:  Peng Yin; Harry M T Choi; Colby R Calvert; Niles A Pierce
Journal:  Nature       Date:  2008-01-17       Impact factor: 49.962

2.  Open source simulation tool for electrophoretic stacking, focusing, and separation.

Authors:  Moran Bercovici; Sanjiva K Lele; Juan G Santiago
Journal:  J Chromatogr A       Date:  2008-12-14       Impact factor: 4.759

3.  Stacking nonenzymatic circuits for high signal gain.

Authors:  Xi Chen; Neima Briggs; Jeremy R McLain; Andrew D Ellington
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-18       Impact factor: 11.205

4.  Laboratory equipment: Cut costs with open-source hardware.

Authors:  Joshua M Pearce
Journal:  Nature       Date:  2014-01-30       Impact factor: 49.962

5.  Analysis of DNA-guided self-assembly of microspheres using imaging flow cytometry.

Authors:  Hao Tang; Ryan Deschner; Peter Allen; Younjin Cho; Patrick Sermas; Alejandro Maurer; Andrew D Ellington; C Grant Willson
Journal:  J Am Chem Soc       Date:  2012-09-06       Impact factor: 15.419

6.  Programmable chemical controllers made from DNA.

Authors:  Yuan-Jyue Chen; Neil Dalchau; Niranjan Srinivas; Andrew Phillips; Luca Cardelli; David Soloveichik; Georg Seelig
Journal:  Nat Nanotechnol       Date:  2013-09-29       Impact factor: 39.213

7.  Open-source 3D-printable optics equipment.

Authors:  Chenlong Zhang; Nicholas C Anzalone; Rodrigo P Faria; Joshua M Pearce
Journal:  PLoS One       Date:  2013-03-27       Impact factor: 3.240

8.  3D Printing with Nucleic Acid Adhesives.

Authors:  Peter B Allen; Zin Khaing; Christine E Schmidt; Andrew D Ellington
Journal:  ACS Biomater Sci Eng       Date:  2014-12-17

9.  Open-source syringe pump library.

Authors:  Bas Wijnen; Emily J Hunt; Gerald C Anzalone; Joshua M Pearce
Journal:  PLoS One       Date:  2014-09-17       Impact factor: 3.240

10.  Open-source colorimeter.

Authors:  Gerald C Anzalone; Alexandra G Glover; Joshua M Pearce
Journal:  Sensors (Basel)       Date:  2013-04-19       Impact factor: 3.576
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  8 in total

1.  3D Printing in the Laboratory: Maximize Time and Funds with Customized and Open-Source Labware.

Authors:  Meghan Coakley; Darrell E Hurt
Journal:  J Lab Autom       Date:  2016-05-19

2.  Purification of single-stranded DNA by co-polymerization with acrylamide and electrophoresis.

Authors:  Tulsi Ram Damase; Andrew D Ellington; Peter B Allen
Journal:  Biotechniques       Date:  2017-06-01       Impact factor: 1.993

3.  Biomimetic Molecular Signaling using DNA Walkers on Microparticles.

Authors:  Tulsi Ram Damase; Adam Spencer; Bamidele Samuel; Peter B Allen
Journal:  Sci Rep       Date:  2017-06-22       Impact factor: 4.379

4.  Open-Source Automated Mapping Four-Point Probe.

Authors:  Handy Chandra; Spencer W Allen; Shane W Oberloier; Nupur Bihari; Jephias Gwamuri; Joshua M Pearce
Journal:  Materials (Basel)       Date:  2017-01-26       Impact factor: 3.623

5.  Simple, low-cost fabrication of acrylic based droplet microfluidics and its use to generate DNA-coated particles.

Authors:  Md Mamunul Islam; Amanda Loewen; Peter B Allen
Journal:  Sci Rep       Date:  2018-06-08       Impact factor: 4.379

6.  3D printed receptacle with diffuser membrane for manipulating pressurized air and water.

Authors:  Tamás Gábor Pálfy; Luca Török; Péter Kalicz; Zoltán Gribovszki
Journal:  HardwareX       Date:  2021-03-29

7.  Professors want to share: preliminary survey results on establishing open-source-endowed professorships.

Authors:  Joshua M Pearce; Alexis S Pascaris; Chelsea Schelly
Journal:  SN Soc Sci       Date:  2022-09-21

Review 8.  A review of open source ventilators for COVID-19 and future pandemics.

Authors:  Joshua M Pearce
Journal:  F1000Res       Date:  2020-03-30
  8 in total

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