Véronique Merle1, Hélène Marini2, Frédéric Di Fiore3, Marion Lottin2, Christian Gray4, Agnès Loeb4, Akpéné Fred2, Nathalie Contentin4, Jean-François Muir5, Luc Thiberville6, Christian Pfister7, Emmanuel Huet8, Christophe Peillon9, Pierre Michel3, Pierre Czernichow2. 1. Department of Epidemiology and Public Health, Rouen University Hospital, 1 rue de Germont, 76031, Rouen cedex, France. Veronique.merle@chu-rouen.fr. 2. Department of Epidemiology and Public Health, Rouen University Hospital, 1 rue de Germont, 76031, Rouen cedex, France. 3. Department of Hepatogastroenterology, Rouen University Hospital, Rouen, France. 4. Henri Becquerel Comprehensive Cancer Center, Rouen, France. 5. Department of Pneumology and Intensive Respiratory Care, Rouen University Hospital, Rouen, France. 6. Department of Pneumology, Rouen University Hospital, Rouen, France. 7. Department of Urology, Rouen University Hospital, Rouen, France. 8. Department of Digestive Surgery, Rouen University Hospital, Rouen, France. 9. Department of General and Thoracic Surgery, Rouen University Hospital, Rouen, France.
Abstract
PURPOSE: Although considered safer than central venous catheters for administration of cancer chemotherapy, totally implanted venous access (TIVA) is associated with adverse events that may impair prognosis and quality of life of patients receiving chemotherapy. Our aim was to assess the feasibility and interest of surveillance of cancer chemotherapy TIVA-adverse events (AE), associated with morbidity-mortality conferences (MMCs) on TIVA-AE. METHODS: We performed a prospective interventional study in two hospitals (a university hospital and a comprehensive care center). For each cancer chemotherapy care pathway within each hospital, we set up surveillance of TIVA-AE and MMC on these events. Patients included in surveillance were those with a TIVA either placed or used for chemotherapy cycles in one of the participating wards. Feasibility of MMC was assessed by the number of MMC meetings that actually took place and the number of participants at each meeting. The interest of MMC was assessed by the number of TIVA-AE identified and analyzed, and the number and type of improvement actions selected and actually implemented. RESULTS: We recorded 0.41 adverse events per 1000 TIVA-day. MMCs were implemented in all care pathways, with sustained pluriprofessional attendance throughout the survey; 39 improvement actions were identified during meetings, and 18 were actually implemented. CONCLUSIONS: Surveillance of TIVA-AE associated with MMC is feasible and helps change practices. It could be useful for improving care of patients undergoing cancer chemotherapy.
PURPOSE: Although considered safer than central venous catheters for administration of cancer chemotherapy, totally implanted venous access (TIVA) is associated with adverse events that may impair prognosis and quality of life of patients receiving chemotherapy. Our aim was to assess the feasibility and interest of surveillance of cancer chemotherapy TIVA-adverse events (AE), associated with morbidity-mortality conferences (MMCs) on TIVA-AE. METHODS: We performed a prospective interventional study in two hospitals (a university hospital and a comprehensive care center). For each cancer chemotherapy care pathway within each hospital, we set up surveillance of TIVA-AE and MMC on these events. Patients included in surveillance were those with a TIVA either placed or used for chemotherapy cycles in one of the participating wards. Feasibility of MMC was assessed by the number of MMC meetings that actually took place and the number of participants at each meeting. The interest of MMC was assessed by the number of TIVA-AE identified and analyzed, and the number and type of improvement actions selected and actually implemented. RESULTS: We recorded 0.41 adverse events per 1000 TIVA-day. MMCs were implemented in all care pathways, with sustained pluriprofessional attendance throughout the survey; 39 improvement actions were identified during meetings, and 18 were actually implemented. CONCLUSIONS: Surveillance of TIVA-AE associated with MMC is feasible and helps change practices. It could be useful for improving care of patients undergoing cancer chemotherapy.
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