Janette Kwok1, Eva Leung1, William Wong1, Kate Leung2, Cheuk Kwong Lee3, Wendy Lam4, Patrick Ip5. 1. Division of Transplantation and Immunogenetics, Department of Pathology and Clinical Biochemistry, Queen Mary Hospital, Hong Kong, Hong Kong. 2. Departmental of Pathology, North District Hospital, Hong Kong, Hong Kong. 3. Department of Blood Collection and Donor Recruitment, Hong Kong Red Cross Blood Transfusion Service, Hong Kong, Hong Kong. 4. Division of Behavioural Sciences, School of Public Health, Faculty of Medicine, University of Hong Kong, Hong Kong, Hong Kong. 5. Department of Paediatrics and Adolescent Medicine, University of Hong Kong, Hong Kong, Hong Kong.
Abstract
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) has become increasingly common for treatment of severe hematological disorders. However, the number of compatible hematopoietic stem cell (HSC) donors is usually limited. Expanding donor pool size would enhance matching success by increasing donor frequency and introducing allelic diversity within the registry. Identifying factors that affect public willingness towards HSC donation allows better strategic recruitment planning to facilitate donor pool expansion. Previous studies in white populations showed knowledge, family attitude, trust towards the healthcare system, fear, self-identity, and social identity are important factors related to HSC donation intention. However, given the differences in cultural and society values that exist across different regions, in particular between the East and West, whether these factors influence HSC donation willingness in Hong Kong remained to be determined. The objective of this study was to identify factors associated with HSC donation motivation in Hong Kong. MATERIAL AND METHODS: A large-scale, cross-sectional, observational study involving 3479 local participants. RESULTS: There is a positive correlation of HSC donation intention with younger age (18-32, OR: 1.80, p≤0·001) and higher education (OR: 1·47, p≤0.001). Better HSCT knowledge is also related to greater HSC donation intention (OR: 2.55, p£0.001). CONCLUSIONS: Our data suggests HSCT education could help to improve donor recruitment and that more resources should be allocated for public education.
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) has become increasingly common for treatment of severe hematological disorders. However, the number of compatible hematopoietic stem cell (HSC) donors is usually limited. Expanding donor pool size would enhance matching success by increasing donor frequency and introducing allelic diversity within the registry. Identifying factors that affect public willingness towards HSC donation allows better strategic recruitment planning to facilitate donor pool expansion. Previous studies in white populations showed knowledge, family attitude, trust towards the healthcare system, fear, self-identity, and social identity are important factors related to HSC donation intention. However, given the differences in cultural and society values that exist across different regions, in particular between the East and West, whether these factors influence HSC donation willingness in Hong Kong remained to be determined. The objective of this study was to identify factors associated with HSC donation motivation in Hong Kong. MATERIAL AND METHODS: A large-scale, cross-sectional, observational study involving 3479 local participants. RESULTS: There is a positive correlation of HSC donation intention with younger age (18-32, OR: 1.80, p≤0·001) and higher education (OR: 1·47, p≤0.001). Better HSCT knowledge is also related to greater HSC donation intention (OR: 2.55, p£0.001). CONCLUSIONS: Our data suggests HSCT education could help to improve donor recruitment and that more resources should be allocated for public education.
Authors: Chuo Yew Ting; Yew Fong Lee; Chien Joo Lim; Rachel Sing Kiat Ting; Mohammad Masrin Md Zahrin; Abu Sufian Ahmad; Jack Siew Yu Wong; Masita Arip; Zubaidah Zakaria; Shahren Ahmad Zaidi Adruce; Jessie Koh Sing Tnay; Yi Shen Wong Journal: Transfus Med Hemother Date: 2020-12-11 Impact factor: 3.747