Literature DB >> 26446662

Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage.

Woong Sun Yoo1, Che Ron Kim1, Byung Jae Kim1, Seong Ki Ahn2, Seong Wook Seo1,3, Ji Myong Yoo1,3, Seong Jae Kim3,4.   

Abstract

Infectious scleritis by Pseudomonas aeruginosa is a well-known vision-threatening disease. In particular, scleral trauma following pterygium surgery may increase the risk of sclera inflammation. Surgical debridement and repair is necessary in patients who do not respond to medical treatments, such as topical and intravenous antibiotics. We reports herein the effectiveness of an autologous perichondrium conchal cartilage graft for infectious scleritis caused by Pseudomonas aeruginosa. This procedure was performed on four eyes of four patients with infectious scleritis who had previously undergone pterygium surgery at Gyeongsang National University Hospital (GNUH), Jinju, Korea from December 2011 to May 2012. Pseudomonas aeruginosa was identified in cultures of necrotic scleral lesion before surgery. The conchal cartilage perichondrium graft was transplanted, and a conjunctival flap was created on the scleral lesion. The autologous perichondrium conchal cartilage graft was successful and visual outcome was stable in all patients, with no reports of graft failure or infection recurrence. In conclusion, autologous perichondrium conchal cartilage graft may be effective in surgical management of Pseudomonal infectious scleritis when non-surgical medical treatment is ineffective. Further studies in larger, diverse populations are warranted to establish the effectiveness of the procedure.

Entities:  

Keywords:  Pseudomonas aeruginosa; Scleritis; autograft; ear cartilage

Mesh:

Substances:

Year:  2015        PMID: 26446662      PMCID: PMC4630068          DOI: 10.3349/ymj.2015.56.6.1738

Source DB:  PubMed          Journal:  Yonsei Med J        ISSN: 0513-5796            Impact factor:   2.759


  10 in total

1.  Identification of cartilage progenitor cells in the adult ear perichondrium: utilization for cartilage reconstruction.

Authors:  Takeshi Togo; Atsushi Utani; Motoko Naitoh; Masayoshi Ohta; Yasumi Tsuji; Noriyuki Morikawa; Motonobu Nakamura; Shigehiko Suzuki
Journal:  Lab Invest       Date:  2006-05       Impact factor: 5.662

2.  Clinical experiences of infectious scleral ulceration: a complication of pterygium operation.

Authors:  C P Lin; M H Shih; M C Tsai
Journal:  Br J Ophthalmol       Date:  1997-11       Impact factor: 4.638

3.  Atypical pneumococcal scleritis after pterygium excision: case report and literature review.

Authors:  Jayter Silva Paula; Maria Lúcia Habib Simão; Eduardo Melani Rocha; Erasmo Romão; Antonio Augusto Velasco Cruz
Journal:  Cornea       Date:  2006-01       Impact factor: 2.651

Review 4.  Scleral patch graft in the management of necrotizing scleritis.

Authors:  Q D Nguyen; C S Foster
Journal:  Int Ophthalmol Clin       Date:  1999

5.  Epidemiology and visual outcomes in patients with infectious scleritis.

Authors:  Kelly L Hodson; Anat Galor; Carol L Karp; Janet L Davis; Thomas A Albini; Victor L Perez; Darlene Miller; Richard K Forster
Journal:  Cornea       Date:  2013-04       Impact factor: 2.651

6.  Microbial scleritis-experience from a developing country.

Authors:  V Jain; P Garg; S Sharma
Journal:  Eye (Lond)       Date:  2008-01-25       Impact factor: 3.775

Review 7.  The impact of new methods of investigation and treatment on the understanding of the pathology of scleral inflammation.

Authors:  P Watson; A Romano
Journal:  Eye (Lond)       Date:  2014-05-30       Impact factor: 3.775

8.  Infectious scleritis in Taiwan-a 10-year review in a tertiary-care hospital.

Authors:  Yeen-Fey Ho; Lung-Kun Yeh; Hsin-Yuan Tan; Hung-Chi Chen; Yeong-Fong Chen; Hsin-Chiung Lin; Shin-Yi Chen; David Hui-Kang; Ching-Hsi Hsiao
Journal:  Cornea       Date:  2014-08       Impact factor: 2.651

9.  The clinical feature of Behçet's disease in Northeastern China.

Authors:  Yingbin Shang; Shixin Han; Jiuhong Li; Qiushi Ren; Fangji Song; Hongduo Chen
Journal:  Yonsei Med J       Date:  2009-10-20       Impact factor: 2.759

10.  Lower lid reconstruction utilizing auricular conchal chondral-perichondral tissue in patients with neoplastic lesions.

Authors:  Pier Camillo Parodi; Fabrizio Calligaris; Fabrizio De Biasio; Giovanna De Maglio; Flavia Miani; Marco Zeppieri
Journal:  Biomed Res Int       Date:  2013-06-20       Impact factor: 3.411

  10 in total
  3 in total

1.  Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective.

Authors:  Sumayya Ahmad; Michelle Lopez; Marwan Attala; Anat Galor; Natalie A Stanciu; Darlene Miller; Leejee Suh; Thomas Albini; Victor L Perez; Carol L Karp; Janet L Davis; Eduardo Alfonso; Richard K Forster; Guillermo Amescua
Journal:  Ocul Immunol Inflamm       Date:  2017-10-17       Impact factor: 3.070

2.  Pseudomonas Scleritis following Pterygium Excision.

Authors:  Winai Chaidaroon; Sumet Supalaset
Journal:  Case Rep Ophthalmol       Date:  2017-07-25

Review 3.  Drug Delivery to the Posterior Segment of the Eye: Biopharmaceutic and Pharmacokinetic Considerations.

Authors:  Rubén Varela-Fernández; Victoria Díaz-Tomé; Andrea Luaces-Rodríguez; Andrea Conde-Penedo; Xurxo García-Otero; Asteria Luzardo-Álvarez; Anxo Fernández-Ferreiro; Francisco J Otero-Espinar
Journal:  Pharmaceutics       Date:  2020-03-16       Impact factor: 6.321

  3 in total

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