Literature DB >> 26445597

Urinary tract infections in women with stress urinary incontinence treated with transobturator suburethral tape and benefit gained from the sublingual polibacterial vaccine.

María F Lorenzo Gómez1, Rafael E Collazos Robles2, Álvaro J Virseda Rodríguez3, María B García Cenador4, José A Mirón Canelo5, Bárbara Padilla Fernández6.   

Abstract

INTRODUCTION AND
OBJECTIVES: Stress urinary incontinence (SUI) and recurrent urinary tract infections (RUTIs) are highly prevalent diseases. Our purpose was to investigate the relationship between RUTIs and surgical correction of SUI with transobturator suburethral tape (TOT) and to describe the benefit gained from a sublingual polibacterial preparation on RUTIs developed after TOT.
MATERIALS AND METHODS: A retrospective study was performed on 420 women who underwent TOT surgery due to SUI between April 2003 and October 2011. Group A: patients without urinary tract infections (UTIs) before TOT (n = 294). Group B: patients with UTIs before TOT (n = 126). VARIABLES: age, personal history, number of UTIs/month prior to and after surgery, appearance of urgent urinary incontinence (UUI) with or without UTIs, response to International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) and Short Form 36 (SF-36) questionnaires.
RESULTS: Group A: 85% dry; 5% UUI; 4% de novo UTIs with good response to antibiotics over 6 days. No RUTIs during the follow-up period, 2% with sporadic UTIs. Group B: 47.61% RUTIs; 52.39% sporadic UTIs; greater incidence of diabetes mellitus (p < 0.0025) and smoking (p < 0.0031) than group A. After TOT: 79.36% dry; 10% RUTIs. After treatment with antibiotics for 6 days and bacterial preparation for 3 months, 82% of patients did not have a UTI anymore. Postoperative cystourethrogram revealed 38% of nondiagnosed cystoceles before TOT. No patient had a postvoiding volume greater than 100 cm(3) after TOT. Improvement of ICIQ-SF (p < 0.001) and SF-36 (p < 0.0004) in both groups.
CONCLUSION: After eliminating bias associated with the tape, the technique and the surgeon's skills, SUI correction may decrease the number of UTIs and improve the quality of life. UTIs disappeared in 82% of patients with RUTIs after TOT.

Entities:  

Keywords:  stress urinary incontinence; transobturator suburethral tape; urinary tract infections

Year:  2015        PMID: 26445597      PMCID: PMC4580092          DOI: 10.1177/1756287215576648

Source DB:  PubMed          Journal:  Ther Adv Urol        ISSN: 1756-2872


  11 in total

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10.  Evaluation of a therapeutic vaccine for the prevention of recurrent urinary tract infections versus prophylactic treatment with antibiotics.

Authors:  M F Lorenzo-Gómez; B Padilla-Fernández; F J García-Criado; J A Mirón-Canelo; A Gil-Vicente; A Nieto-Huertos; J M Silva-Abuin
Journal:  Int Urogynecol J       Date:  2012-07-18       Impact factor: 2.894

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