Literature DB >> 2644125

The yeast gene, DBF4, essential for entry into S phase is cell cycle regulated.

J W Chapman1, L H Johnston.   

Abstract

The DBF4 gene of Saccharomyces cerevisiae, required for events preceding DNA replication, was isolated and located to 2.8 kb of DNA from chromosome IV. Genetic mapping showed the gene to be linked to TRP1. The DBF4 transcript is 2.4 kb in length and shows periodic regulation within the cell cycle. The peak of expression occurs late in G1, coincident with several genes involved in DNA synthesis. The behavior of the message is consistent with that expected for a stable, cell cycle regulated transcript.

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Year:  1989        PMID： 2644125     DOI： 10.1016/0014-4827(89)90068-2

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN： 0014-4827            Impact factor:   3.905


  35 in total

1.  Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex.

Authors:  M F Ferreira; C Santocanale; L S Drury; J F Diffley
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

2.  A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage.

Authors:  T Takeda; K Ogino; E Matsui; M K Cho; H Kumagai; T Miyake; K Arai; H Masai
Journal:  Mol Cell Biol       Date:  1999-08       Impact factor: 4.272

3.  Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability.

Authors:  G Oshiro; J C Owens; Y Shellman; R A Sclafani; J J Li
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

4.  Cell cycle regulation of DNA replication initiator factor Dbf4p.

Authors:  L Cheng; T Collyer; C F Hardy
Journal:  Mol Cell Biol       Date:  1999-06       Impact factor: 4.272

5.  Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast.

Authors:  T Takeda; K Ogino; K Tatebayashi; H Ikeda; H Masai
Journal:  Mol Biol Cell       Date:  2001-05       Impact factor: 4.138

Review 6.  Cell cycle control of DNA synthesis in budding yeast.

Authors:  L H Johnston; N F Lowndes
Journal:  Nucleic Acids Res       Date:  1992-05-25       Impact factor: 16.971

Review 7.  Mechanisms and regulation of DNA replication initiation in eukaryotes.

Authors:  Matthew W Parker; Michael R Botchan; James M Berger
Journal:  Crit Rev Biochem Mol Biol       Date:  2017-01-17       Impact factor: 8.250

8.  Hypomorphic mutation in an essential cell-cycle kinase causes growth retardation and impaired spermatogenesis.

Authors:  Jung Min Kim; Naofumi Takemoto; Ken-ichi Arai; Hisao Masai
Journal:  EMBO J       Date:  2003-10-01       Impact factor: 11.598

9.  Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases.

Authors:  T Tanaka; K Nasmyth
Journal:  EMBO J       Date:  1998-09-01       Impact factor: 11.598

10.  A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5.

Authors:  K Kitada; A L Johnson; L H Johnston; A Sugino
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272
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