Literature DB >> 26441248

Regenerative medicine: Hepatic progenitor cells up their game in the therapeutic stakes.

Malcolm R Alison1, Wey-Ran Lin2.   

Abstract

Bipotential hepatic progenitor cells (HPCs) are recognized as making modest contributions to hepatocyte regeneration, though never credited with major liver repopulation. A new study in mice demonstrates HPCs can make a massive contribution to hepatocyte replacement, suggesting HPCs have the potential to be an effective cell therapy for liver failure.

Entities:  

Mesh：

Year:  2015        PMID： 26441248     DOI： 10.1038/nrgastro.2015.168

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN： 1759-5045            Impact factor:   46.802


  9 in total

Review 1.  Liver development update: new embryo models, cell lineage control, and morphogenesis.

Authors:  Frederic Lemaigre; Kenneth S Zaret
Journal:  Curr Opin Genet Dev       Date:  2004-10       Impact factor: 5.578

Review 2.  Wound healing in the liver with particular reference to stem cells.

Authors:  M Alison; M Golding; C Sarraf
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1998-06-29       Impact factor: 6.237

3.  Liver stem cells, where art thou?

Authors:  Markus Grompe
Journal:  Cell Stem Cell       Date:  2014-09-04       Impact factor: 24.633

4.  Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.

Authors:  Yann Malato; Syed Naqvi; Nina Schürmann; Raymond Ng; Bruce Wang; Joan Zape; Mark A Kay; Dirk Grimm; Holger Willenbring
Journal:  J Clin Invest       Date:  2011-11-21       Impact factor: 14.808

5.  Direct and indirect contribution of human embryonic stem cell-derived hepatocyte-like cells to liver repair in mice.

Authors:  Dong-Hun Woo; Suel-Kee Kim; Hee-Joung Lim; Jeonghoon Heo; Hyung Soon Park; Gum-Yong Kang; Sung-Eun Kim; Hyun-Ju You; Daniel J Hoeppner; Youngchul Kim; Heechung Kwon; Tae Hyun Choi; Joo Hee Lee; Su Hee Hong; Kang Won Song; Eun-Kyung Ahn; Josh G Chenoweth; Paul J Tesar; Ronald D G McKay; Jong-Hoon Kim
Journal:  Gastroenterology       Date:  2011-12-02       Impact factor: 22.682

6.  Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.

Authors:  Kenichiro Furuyama; Yoshiya Kawaguchi; Haruhiko Akiyama; Masashi Horiguchi; Sota Kodama; Takeshi Kuhara; Shinichi Hosokawa; Ashraf Elbahrawy; Tsunemitsu Soeda; Masayuki Koizumi; Toshihiko Masui; Michiya Kawaguchi; Kyoichi Takaori; Ryuichiro Doi; Eiichiro Nishi; Ryosuke Kakinoki; Jian Min Deng; Richard R Behringer; Takashi Nakamura; Shinji Uemoto
Journal:  Nat Genet       Date:  2010-11-28       Impact factor: 38.330

Review 7.  Cell therapy for liver disease: From liver transplantation to cell factory.

Authors:  Stuart J Forbes; Sanjeev Gupta; Anil Dhawan
Journal:  J Hepatol       Date:  2015-04       Impact factor: 25.083

8.  Hepatic progenitor cells of biliary origin with liver repopulation capacity.

Authors:  Wei-Yu Lu; Thomas G Bird; Luke Boulter; Atsunori Tsuchiya; Alicia M Cole; Trevor Hay; Rachel V Guest; Davina Wojtacha; Tak Yung Man; Alison Mackinnon; Rachel A Ridgway; Timothy Kendall; Michael J Williams; Thomas Jamieson; Alex Raven; David C Hay; John P Iredale; Alan R Clarke; Owen J Sansom; Stuart J Forbes
Journal:  Nat Cell Biol       Date:  2015-07-20       Impact factor: 28.824

9.  Mouse liver repopulation with hepatocytes generated from human fibroblasts.

Authors:  Saiyong Zhu; Milad Rezvani; Jack Harbell; Aras N Mattis; Alan R Wolfe; Leslie Z Benet; Holger Willenbring; Sheng Ding
Journal:  Nature       Date:  2014-02-23       Impact factor: 49.962
  9 in total

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