Literature DB >> 26435645

Characteristics and outcome of patients with difficult weaning from mechanical ventilation: an 18 years' experience of a respiratory intermediate unit attached to a pulmonary department.

V Tsara1, N Moisiadis1, M Antoniadou1, E Serasli1.   

Abstract

BACKGROUND: Respiratory dysfunction often persists in post intensive care unit (ICU) patients and intermediate care facilities have been established to ensure the continuous of appropriate care.
METHODS: The data of patients with difficult weaning from mechanical ventilation admitted to a respiratory intermediate unit (RIU) attached to a pulmonary department of a General Hospital, were retrospectively analyzed. Clinical characteristics, weaning from mechanical ventilation and tracheostomy, ICU readmission and RIU mortality were examined over a period of 18 years (1993- 2010) that was randomly divided into three six-year-periods.
RESULTS: A total of 548 patients (age 56.7±17.9 years) [mean ± standard deviation (SD)], of whom 80% with tracheostomy in place and 37.6% with pressure ulcers, were examined. The ICU stay was 30.1±24.7 days (mean ± SD) and increased over time (p<0.05). Patients' baseline disorders were: chronic respiratory disease (41.3%), chronic cardiovascular diseases (10.6%), neuromuscular disease (22.8%) and miscellaneous (25.3%). The length of RIU stay (22.8±19.5 days) was constant over the examined periods but an increase in age and maintenance of tracheostomy were observed; 80% of patients were liberated from mechanical ventilation and 58.5% from tracheostomy, whereas the RIU mortality was 15%.
CONCLUSION: In their vast majority patients with chronic respiratory failure, who were admitted to RIU,were weaned from mechanical ventilation, although in a substantial percentage the maintenance of tracheostomy was mandatory after discharge. Hippokratia 2015, 19 (1): 37-40.

Entities:  

Keywords:  RICU; Respiratory intermediate unit; chronic respiratory failure; mechanical ventilation; tracheostomy

Year:  2015        PMID: 26435645      PMCID: PMC4574584     

Source DB:  PubMed          Journal:  Hippokratia        ISSN: 1108-4189            Impact factor:   0.471


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  2 in total

1.  Weaning from mechanical ventilation in people with neuromuscular disease: protocol for a systematic review.

Authors:  Saint Clair Gomes Bernardes Neto; Rodrigo Torres; Íllia Lima; Vanessa R Resqueti; Guilherme A F Fregonezi
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Review 2.  Mortality outcomes of patients on chronic mechanical ventilation in different care settings: A systematic review.

Authors:  Stephanie M Sison; Gayathri K Sivakumar; Christine Caufield-Noll; William B Greenough; Esther S Oh; Panagis Galiatsatos
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