Y Kim1, Y Je1. 1. Department of Food and Nutrition, Kyung Hee University, Seoul, South Korea.
Abstract
AIMS: To conduct a systematic review and meta-analysis of epidemiological studies in order to assess quantitatively the effect of dairy consumption on risk of metabolic syndrome. METHODS: We searched for eligible studies published up to March 2015 through the PubMed and Embase databases and reviewed the references of relevant articles. Random-effects models were used to calculate the pooled relative risks with 95% CIs after adjusting for several confounders. RESULTS: We identified nine prospective cohort studies including a total of 35 379 subjects and 7322 incident cases of metabolic syndrome, and 12 cross-sectional studies including 37 706 subjects. In the meta-analysis of prospective cohort studies, the pooled relative risk of incidence of metabolic syndrome for the highest vs. the lowest category of dairy consumption was 0.85 (95% CI 0.73-0.98), and for a 1-serving/day increment of dairy consumption, the pooled relative risk was 0.88 (95% CI 0.82-0.95). In the meta-analysis of cross-sectional studies, the pooled relative risk of prevalence of metabolic syndrome for the highest vs. the lowest category of dairy consumption was 0.73 (95% CI 0.63-0.86). The association was not significantly different by geographical region, follow-up time and adjustment factors. CONCLUSION: Our findings indicate that dairy consumption is inversely associated with the incidence and prevalence of metabolic syndrome. Further well-designed cohort studies and randomized controlled trials are warranted to provide definitive evidence.
AIMS: To conduct a systematic review and meta-analysis of epidemiological studies in order to assess quantitatively the effect of dairy consumption on risk of metabolic syndrome. METHODS: We searched for eligible studies published up to March 2015 through the PubMed and Embase databases and reviewed the references of relevant articles. Random-effects models were used to calculate the pooled relative risks with 95% CIs after adjusting for several confounders. RESULTS: We identified nine prospective cohort studies including a total of 35 379 subjects and 7322 incident cases of metabolic syndrome, and 12 cross-sectional studies including 37 706 subjects. In the meta-analysis of prospective cohort studies, the pooled relative risk of incidence of metabolic syndrome for the highest vs. the lowest category of dairy consumption was 0.85 (95% CI 0.73-0.98), and for a 1-serving/day increment of dairy consumption, the pooled relative risk was 0.88 (95% CI 0.82-0.95). In the meta-analysis of cross-sectional studies, the pooled relative risk of prevalence of metabolic syndrome for the highest vs. the lowest category of dairy consumption was 0.73 (95% CI 0.63-0.86). The association was not significantly different by geographical region, follow-up time and adjustment factors. CONCLUSION: Our findings indicate that dairy consumption is inversely associated with the incidence and prevalence of metabolic syndrome. Further well-designed cohort studies and randomized controlled trials are warranted to provide definitive evidence.
Authors: Pablo Pérez-Martínez; Dimitri P Mikhailidis; Vasilios G Athyros; Mónica Bullo; Patrick Couture; María I Covas; Lawrence de Koning; Javier Delgado-Lista; Andrés Díaz-López; Christian A Drevon; Ramón Estruch; Katherine Esposito; Montserrat Fitó; Marta Garaulet; Dario Giugliano; Antonio García-Ríos; Niki Katsiki; Genovefa Kolovou; Benoît Lamarche; Maria Ida Maiorino; Guillermo Mena-Sánchez; Araceli Muñoz-Garach; Dragana Nikolic; José M Ordovás; Francisco Pérez-Jiménez; Manfredi Rizzo; Jordi Salas-Salvadó; Helmut Schröder; Francisco J Tinahones; Rafael de la Torre; Ben van Ommen; Suzan Wopereis; Emilio Ros; José López-Miranda Journal: Nutr Rev Date: 2017-05-01 Impact factor: 7.110