| Literature DB >> 26429349 |
Claas Ahlrichs1, Albert Samà2, Michael Lawo3, Joan Cabestany2, Daniel Rodríguez-Martín2, Carlos Pérez-López2, Dean Sweeney4, Leo R Quinlan4, Gearòid Ò Laighin4, Timothy Counihan5, Patrick Browne5, Lewy Hadas6, Gabriel Vainstein6, Alberto Costa7,8, Roberta Annicchiarico7, Sheila Alcaine9, Berta Mestre9, Paola Quispe9, Àngels Bayes9, Alejandro Rodríguez-Molinero4.
Abstract
Freezing of gait (FOG) is a common motor symptom of Parkinson's disease (PD), which presents itself as an inability to initiate or continue gait. This paper presents a method to monitor FOG episodes based only on acceleration measurements obtained from a waist-worn device. Three approximations of this method are tested. Initially, FOG is directly detected by a support vector machine (SVM). Then, classifier's outputs are aggregated over time to determine a confidence value, which is used for the final classification of freezing (i.e., second and third approach). All variations are trained with signals of 15 patients and evaluated with signals from another 5 patients. Using a linear SVM kernel, the third approach provides 98.7% accuracy and a geometric mean of 96.1%. Moreover, it is investigated whether frequency features are enough to reliably detect FOG. Results show that these features allow the method to detect FOG with accuracies above 90% and that frequency features enable a reliable monitoring of FOG by using simply a waist sensor.Entities:
Keywords: Freezing of Gait; Machine learning; Parkinson’s disease; Support vector machines
Mesh:
Year: 2015 PMID: 26429349 DOI: 10.1007/s11517-015-1395-3
Source DB: PubMed Journal: Med Biol Eng Comput ISSN: 0140-0118 Impact factor: 2.602