Literature DB >> 26429349

Detecting freezing of gait with a tri-axial accelerometer in Parkinson's disease patients.

Claas Ahlrichs1, Albert Samà2, Michael Lawo3, Joan Cabestany2, Daniel Rodríguez-Martín2, Carlos Pérez-López2, Dean Sweeney4, Leo R Quinlan4, Gearòid Ò Laighin4, Timothy Counihan5, Patrick Browne5, Lewy Hadas6, Gabriel Vainstein6, Alberto Costa7,8, Roberta Annicchiarico7, Sheila Alcaine9, Berta Mestre9, Paola Quispe9, Àngels Bayes9, Alejandro Rodríguez-Molinero4.   

Abstract

Freezing of gait (FOG) is a common motor symptom of Parkinson's disease (PD), which presents itself as an inability to initiate or continue gait. This paper presents a method to monitor FOG episodes based only on acceleration measurements obtained from a waist-worn device. Three approximations of this method are tested. Initially, FOG is directly detected by a support vector machine (SVM). Then, classifier's outputs are aggregated over time to determine a confidence value, which is used for the final classification of freezing (i.e., second and third approach). All variations are trained with signals of 15 patients and evaluated with signals from another 5 patients. Using a linear SVM kernel, the third approach provides 98.7% accuracy and a geometric mean of 96.1%. Moreover, it is investigated whether frequency features are enough to reliably detect FOG. Results show that these features allow the method to detect FOG with accuracies above 90% and that frequency features enable a reliable monitoring of FOG by using simply a waist sensor.

Entities:  

Keywords:  Freezing of Gait; Machine learning; Parkinson’s disease; Support vector machines

Mesh:

Year:  2015        PMID: 26429349     DOI: 10.1007/s11517-015-1395-3

Source DB:  PubMed          Journal:  Med Biol Eng Comput        ISSN: 0140-0118            Impact factor:   2.602


  18 in total

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Journal:  J Neural Transm (Vienna)       Date:  1999       Impact factor: 3.575

2.  An essay on the shaking palsy. 1817.

Authors:  James Parkinson
Journal:  J Neuropsychiatry Clin Neurosci       Date:  2002       Impact factor: 2.198

Review 3.  Effects of external rhythmical cueing on gait in patients with Parkinson's disease: a systematic review.

Authors:  I Lim; E van Wegen; C de Goede; M Deutekom; A Nieuwboer; A Willems; D Jones; L Rochester; G Kwakkel
Journal:  Clin Rehabil       Date:  2005-10       Impact factor: 3.477

4.  Parkinsonism: onset, progression and mortality.

Authors:  M M Hoehn; M D Yahr
Journal:  Neurology       Date:  1967-05       Impact factor: 9.910

5.  Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.

Authors:  A J Hughes; S E Daniel; L Kilford; A J Lees
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-03       Impact factor: 10.154

6.  Wearable assistant for Parkinson's disease patients with the freezing of gait symptom.

Authors:  Marc Bächlin; Meir Plotnik; Daniel Roggen; Inbal Maidan; Jeffrey M Hausdorff; Nir Giladi; Gerhard Tröster
Journal:  IEEE Trans Inf Technol Biomed       Date:  2009-11-10

Review 7.  Visual signs and symptoms of Parkinson's disease.

Authors:  Richard A Armstrong
Journal:  Clin Exp Optom       Date:  2008-03       Impact factor: 2.742

8.  Ambulatory monitoring of freezing of gait in Parkinson's disease.

Authors:  Steven T Moore; Hamish G MacDougall; William G Ondo
Journal:  J Neurosci Methods       Date:  2007-09-02       Impact factor: 2.390

Review 9.  Falls and freezing of gait in Parkinson's disease: a review of two interconnected, episodic phenomena.

Authors:  Bastiaan R Bloem; Jeffrey M Hausdorff; Jasper E Visser; Nir Giladi
Journal:  Mov Disord       Date:  2004-08       Impact factor: 10.338

Review 10.  Characterizing freezing of gait in Parkinson's disease: models of an episodic phenomenon.

Authors:  Alice Nieuwboer; Nir Giladi
Journal:  Mov Disord       Date:  2013-09-15       Impact factor: 10.338

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  24 in total

Review 1.  Clinical and methodological challenges for assessing freezing of gait: Future perspectives.

Authors:  Martina Mancini; Bastiaan R Bloem; Fay B Horak; Simon J G Lewis; Alice Nieuwboer; Jorik Nonnekes
Journal:  Mov Disord       Date:  2019-05-02       Impact factor: 10.338

2.  A novel single-sensor-based method for the detection of gait-cycle breakdown and freezing of gait in Parkinson's disease.

Authors:  Taylor Chomiak; Wenbiao Xian; Zhong Pei; Bin Hu
Journal:  J Neural Transm (Vienna)       Date:  2019-06-01       Impact factor: 3.575

3.  Understanding the Physiological Significance of Four Inertial Gait Features in Multiple Sclerosis.

Authors:  Sriram Raju Dandu; Matthew M Engelhard; Asma Qureshi; Jiaqi Gong; John C Lach; Maite Brandt-Pearce; Myla D Goldman
Journal:  IEEE J Biomed Health Inform       Date:  2018-01       Impact factor: 5.772

Review 4.  Machine learning in human movement biomechanics: Best practices, common pitfalls, and new opportunities.

Authors:  Eni Halilaj; Apoorva Rajagopal; Madalina Fiterau; Jennifer L Hicks; Trevor J Hastie; Scott L Delp
Journal:  J Biomech       Date:  2018-09-13       Impact factor: 2.712

5.  Touchscreen typing-pattern analysis for detecting fine motor skills decline in early-stage Parkinson's disease.

Authors:  Dimitrios Iakovakis; Stelios Hadjidimitriou; Vasileios Charisis; Sevasti Bostantzopoulou; Zoe Katsarou; Leontios J Hadjileontiadis
Journal:  Sci Rep       Date:  2018-05-16       Impact factor: 4.379

6.  Real-Time Classification of Patients with Balance Disorders vs. Normal Subjects Using a Low-Cost Small Wireless Wearable Gait Sensor.

Authors:  Bhargava Teja Nukala; Taro Nakano; Amanda Rodriguez; Jerry Tsay; Jerry Lopez; Tam Q Nguyen; Steven Zupancic; Donald Y C Lie
Journal:  Biosensors (Basel)       Date:  2016-11-29

Review 7.  Freezing of gait and fall detection in Parkinson's disease using wearable sensors: a systematic review.

Authors:  Ana Lígia Silva de Lima; Luc J W Evers; Tim Hahn; Lauren Bataille; Jamie L Hamilton; Max A Little; Yasuyuki Okuma; Bastiaan R Bloem; Marjan J Faber
Journal:  J Neurol       Date:  2017-03-01       Impact factor: 4.849

Review 8.  Quantitative Analysis of Motor Status in Parkinson's Disease Using Wearable Devices: From Methodological Considerations to Problems in Clinical Applications.

Authors:  Masahiko Suzuki; Hiroshi Mitoma; Mitsuru Yoneyama
Journal:  Parkinsons Dis       Date:  2017-05-18

Review 9.  The Practicalities of Assessing Freezing of Gait.

Authors:  Claudia Barthel; Elizabeth Mallia; Bettina Debû; Bastiaan R Bloem; Murielle Ursulla Ferraye
Journal:  J Parkinsons Dis       Date:  2016-10-19       Impact factor: 5.568

10.  l-DOPA and Freezing of Gait in Parkinson's Disease: Objective Assessment through a Wearable Wireless System.

Authors:  Antonio Suppa; Ardian Kita; Giorgio Leodori; Alessandro Zampogna; Ettore Nicolini; Paolo Lorenzi; Rosario Rao; Fernanda Irrera
Journal:  Front Neurol       Date:  2017-08-14       Impact factor: 4.003

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