Literature DB >> 26424342

Perioperative morbidity and mortality after lumbar trauma in the elderly.

Ethan A Winkler1, John K Yue1, Harjus Birk1, Caitlin K Robinson1, Geoffrey T Manley1, Sanjay S Dhall1, Phiroz E Tarapore1.   

Abstract

OBJECT Traumatic fractures of the thoracolumbar spine are common injuries, accounting for approximately 90% of all spinal trauma. Lumbar spine trauma in the elderly is a growing public health problem with relatively little evidence to guide clinical management. The authors sought to characterize the complications, morbidity, and mortality associated with surgical and nonsurgical management in elderly patients with traumatic fractures of the lumbar spine. METHODS Using the National Sample Program of the National Trauma Data Bank, the authors performed a retrospective analysis of patients ≥ 55 years of age who had traumatic fracture to the lumbar spine. This group was divided into middle-aged (55-69 years) and elderly (≥ 70 years) cohorts. Cohorts were subdivided into nonoperative, vertebroplasty or kyphoplasty, noninstrumented surgery, and instrumented surgery. Univariate and multivariable analyses were used to characterize and identify predictors of medical and surgical complications, mortality, hospital length of stay, ICU length of stay, number of days on ventilator, and hospital discharge in each subgroup. Adjusted odds ratios, mean differences, and associated 95% CIs were reported. Statistical significance was assessed at p < 0.05, and the Bonferroni correction for multiple comparisons was applied for each outcome analysis. RESULTS Between 2003 and 2012, 22,835 people met the inclusion criteria, which represents 94,103 incidents nationally. Analyses revealed a similar medical and surgical complication profile between age groups. The most prevalent medical complications were pneumonia (7.0%), acute respiratory distress syndrome (3.6%), and deep venous thrombosis (3%). Surgical site infections occurred in 6.3% of cases. Instrumented surgery was associated with the highest odds of each complication (p < 0.001). The inpatient mortality rate was 6.8% for all subjects. Multivariable analyses demonstrated that age ≥ 70 years was an independent predictor of mortality (OR 3.16, 95% CI 2.77-3.60), whereas instrumented surgery (multivariable OR 0.38, 95% CI 0.28-0.52) and vertebroplasty or kyphoplasty (OR 0.27, 95% CI 0.17-0.45) were associated with decreased odds of death. In surviving patients, both older age (OR 0.32, 95% CI 0.30-0.34) and instrumented fusion (OR 0.37, 95% CI 0.33-0.41) were associated with decreased odds of discharge to home. CONCLUSIONS The present study confirms that lumbar surgery in the elderly is associated with increased morbidity. In particular, instrumented fusion is associated with periprocedural complications, prolonged hospitalization, and a decreased likelihood of being discharged home. However, fusion surgery is also associated with reduced mortality. Age alone should not be an exclusionary factor in identifying surgical candidates for instrumented lumbar spinal fusion. Future studies are needed to confirm these findings.

Entities:  

Keywords:  ARDS = acute respiratory distress syndrome; CCI = Charlson Comorbidity Index; ED = emergency department; GCS = Glasgow Coma Scale; HR = hazard ratio; ISS = Injury Severity Score; LOS = length of stay; NSP = National Sample Program; NTDB = National Trauma Data Bank; SBP = systolic blood pressure; elderly; lumbar spine fracture; morbidity; mortality; trauma

Mesh:

Year:  2015        PMID: 26424342     DOI: 10.3171/2015.7.FOCUS15270

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN: 1092-0684            Impact factor:   4.047


  8 in total

1.  Incidence of Respiratory Complications Following Lumbar Spine Surgery.

Authors:  Rajan Murgai; Anthony D'Oro; Patrick Heindel; Kyle Schoell; Kaku Barkoh; Zorica Buser; Jeffrey C Wang
Journal:  Int J Spine Surg       Date:  2018-12-21

2.  Outcomes and Complications of Minimally Invasive Surgery of the Lumbar Spine in the Elderly.

Authors:  Mauricio J Avila; Christina M Walter; Ali A Baaj
Journal:  Cureus       Date:  2016-03-05

3.  Perioperative "remote" acute lung injury: recent update.

Authors:  Zhaosheng Jin; Ka Chun Suen; Daqing Ma
Journal:  J Biomed Res       Date:  2017-01-19

4.  High-Risk Subgroup Membership Is a Predictor of 30-Day Morbidity Following Anterior Lumbar Fusion.

Authors:  Rachel S Bronheim; Jun S Kim; John Di Capua; Nathan J Lee; Parth Kothari; Sulaiman Somani; Kevin Phan; Samuel K Cho
Journal:  Global Spine J       Date:  2017-04-11

5.  Anterior Versus Transforaminal Lumbar Interbody Fusion: Perioperative Risk Factors and 30-Day Outcomes.

Authors:  Pavan S Upadhyayula; Erik I Curtis; John K Yue; Nikki Sidhu; Joseph D Ciacci
Journal:  Int J Spine Surg       Date:  2018-10-15

6.  Rates of Mortality in Lumbar Spine Surgery and Factors Associated With Its Occurrence Over a 10-Year Period: A Study of 803,949 Patients in the Nationwide Inpatient Sample.

Authors:  Gregory Wyatt Poorman; John Y Moon; Charles Wang; Samantha R Horn; Bryan M Beaubrun; Olivia J Bono; Anne-Marie Francis; Cyrus M Jalai; Peter G Passias
Journal:  Int J Spine Surg       Date:  2018-10-15

7.  Factors affecting postoperative mortality of patients with insufficient union following osteoporotic vertebral fractures and impact of preoperative serum albumin on mortality.

Authors:  Tetsuro Ohba; Hiroshi Yokomichi; Kensuke Koyama; Nobuki Tanaka; Kotaro Oda; Hirotaka Haro
Journal:  BMC Musculoskelet Disord       Date:  2020-08-10       Impact factor: 2.362

8.  Evaluation of the 10 Years' Association Between DXA Screening and Mortality in Patients Who Received Vertebroplasty in the Taiwan Population.

Authors:  Yu-Ying Wu; I-Fan Lin; Po-Yuan Chen; Cheng-Kai Lin; Cheng-Chun Wu; Cheng-Loong Liang; Yi-Che Lee; Chi-Wei Lin; Wei-Leng Chin; Hao Kuang Wang
Journal:  Risk Manag Healthc Policy       Date:  2021-07-14
  8 in total

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