Literature DB >> 2642408

The alpha 1-antitrypsin gene and its mutations. Clinical consequences and strategies for therapy.

R G Crystal1, M L Brantly, R C Hubbard, D T Curiel, D J States, M D Holmes.   

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Year:  1989        PMID： 2642408     DOI： 10.1378/chest.95.1.196

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


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  46 in total

Review 1.  Topical corticosteroids: back to basics.

Authors:  N P Lee; E R Arriola
Journal:  West J Med       Date:  1999 Nov-Dec

2.  De novo mutation within the intron-exon junction in the PiZ allele of the alpha-1-antitrypsin gene.

Authors:  A L Schwarzman; A Kowalska; J Rujner; M S Vlasov; V S Gaitskhoki
Journal:  Hum Genet       Date:  1992 Sep-Oct       Impact factor: 4.132

Review 3.  Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.

Authors:  Brice Korkmaz; Marshall S Horwitz; Dieter E Jenne; Francis Gauthier
Journal:  Pharmacol Rev       Date:  2010-12       Impact factor: 25.468

4.  Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders.

Authors:  Ann E Tilley; Michelle R Staudt; Jacqueline Salit; Benjamin Van de Graaf; Yael Strulovici-Barel; Robert J Kaner; Thomas Vincent; Francisco Agosto-Perez; Jason G Mezey; Benjamin A Raby; Ronald G Crystal
Journal:  Am J Respir Crit Care Med       Date:  2016-01-15       Impact factor: 21.405

5.  Expression of the secretory leukoprotease inhibitor gene in epithelial cells.

Authors:  T Abe; N Kobayashi; K Yoshimura; B C Trapnell; H Kim; R C Hubbard; M T Brewer; R C Thompson; R G Crystal
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

Review 6.  Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.

Authors:  R G Crystal
Journal:  J Clin Invest       Date:  1990-05       Impact factor: 14.808

7.  Bronchoalveolar fluid is not a major hindrance to virus-mediated gene therapy in cystic fibrosis.

Authors:  C P Rooney; G M Denning; B P Davis; D M Flaherty; J A Chiorini; J Zabner
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

Review 8.  Current status of alpha-1-antitrypsin replacement therapy: recommendations for the management of patients with severe hereditary deficiency. Ad Hoc Committee on Alpha-1-Antitrypsin Replacement Therapy of the Standards Committee, Canadian Thoracic Society.

Authors: 
Journal:  CMAJ       Date:  1992-03-15       Impact factor: 8.262

Review 9.  Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease.

Authors:  Maria J Chiuchiolo; Ronald G Crystal
Journal:  Ann Am Thorac Soc       Date:  2016-08

10.  Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency.

Authors:  Caitriona McLean; Catherine M Greene; Noel G McElvaney
Journal:  Biologics       Date:  2009-07-13
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