Literature DB >> 26418312

A Self-Assembled Albumin-Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging.

Qian Chen1, Xiaodong Liu2, Jiawen Chen1, Jianfeng Zeng3, Zhenping Cheng2, Zhuang Liu1.   

Abstract

A photoacoustic nanoprobe is self-assembled from human serum albumin and two types of dye molecules, one is inert to pH and the other is pH sensitive. This probe and the quantitative ratiometric photoacoustic pH imaging method are shown to have high safety, be easy-to-operate, and have depth-independent accuracy for real-time in vivo pH imaging of entire tumors. These features make them promising for future cancer prognosis and therapeutic planning.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  albumin; in vivo pH detection; nanoprobes; photoacoustic imaging; self-assembly

Mesh：

Substances：

Year:  2015        PMID： 26418312     DOI： 10.1002/adma.201503194

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  50 in total

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Review 10.  What is new in nanoparticle-based photoacoustic imaging?

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