Frederick Wolfe1, Mary-Ann Fitzcharles2, Don L Goldenberg3, Winfried Häuser4, Robert L Katz5, Philip J Mease6, Anthony S Russell7, I Jon Russell8, Brian Walitt9. 1. National Data Bank for Rheumatic Diseases and the University of Kansas School of Medicine, Wichita, Kansas. 2. Mary-Ann Fitzcharles, MBChB, McGill University Health Center, Montreal, Quebec, Canada. 3. Newton-Wellesley Hospital and Tufts University School of Medicine, Newton,Massachusetts. 4. Klinikum Saarbrücken and Technische Universität München, Munich, Germany. 5. Rush Medical College, Chicago, Illinois. 6. Swedish Medical Center and the University of Washington, Seattle. 7. University of Alberta, Edmonton, Alberta, Canada. 8. Fibromyalgia Research and Consulting, San Antonio, Texas. 9. National Institute of Nursing Research, National Institutes of Health, Bethesda, Maryland.
Abstract
OBJECTIVE: The American College of Rheumatology (ACR) 2010 preliminary fibromyalgia diagnostic criteria require symptom ascertainment by physicians. The 2011 survey or research modified ACR criteria use only patient self-report. We compared physician-based (MD) (2010) and patient-based (PT) (2011) criteria and criteria components to determine the degree of agreement between criteria methodology. METHODS: We studied prospectively collected, previously unreported rheumatology practice data from 514 patients and 30 physicians in the ACR 2010 study. We evaluated the widespread pain index, polysymptomatic distress (PSD) scale, tender point count (TPC), and fibromyalgia diagnosis using 2010 and 2011 rules. Bland-Altman 95% limits of agreement (LOA), kappa statistic, Lin's concordance coefficient, and the area under the receiver operating curve (ROC) were used to measure agreement and discrimination. RESULTS: MD and PT diagnostic agreement was substantial (83.4%, κ = 0.67). PSD scores differed slightly (12.3 MD, 12.8 PT; P = 0.213). LOA for PSD were -8.5 and 7.7, with bias of -0.42. The TPC was strongly associated with both the MD (r = 0.779) and PT PSD scales (r = 0.702). CONCLUSION: There was good agreement in MD and PT fibromyalgia diagnosis and other measures among rheumatology patients. Low bias scores indicate consistent results for physician and patient measures, but large values for LOA indicate many widely discordant pairs. There is acceptable agreement in diagnosis and PSD for research, but insufficient agreement for clinical decisions and diagnosis. We suggest adjudication of symptom data by patients and physicians, as recommended by the 2010 ACR criteria.
OBJECTIVE: The American College of Rheumatology (ACR) 2010 preliminary fibromyalgia diagnostic criteria require symptom ascertainment by physicians. The 2011 survey or research modified ACR criteria use only patient self-report. We compared physician-based (MD) (2010) and patient-based (PT) (2011) criteria and criteria components to determine the degree of agreement between criteria methodology. METHODS: We studied prospectively collected, previously unreported rheumatology practice data from 514 patients and 30 physicians in the ACR 2010 study. We evaluated the widespread pain index, polysymptomatic distress (PSD) scale, tender point count (TPC), and fibromyalgia diagnosis using 2010 and 2011 rules. Bland-Altman 95% limits of agreement (LOA), kappa statistic, Lin's concordance coefficient, and the area under the receiver operating curve (ROC) were used to measure agreement and discrimination. RESULTS: MD and PT diagnostic agreement was substantial (83.4%, κ = 0.67). PSD scores differed slightly (12.3 MD, 12.8 PT; P = 0.213). LOA for PSD were -8.5 and 7.7, with bias of -0.42. The TPC was strongly associated with both the MD (r = 0.779) and PT PSD scales (r = 0.702). CONCLUSION: There was good agreement in MD and PT fibromyalgia diagnosis and other measures among rheumatologypatients. Low bias scores indicate consistent results for physician and patient measures, but large values for LOA indicate many widely discordant pairs. There is acceptable agreement in diagnosis and PSD for research, but insufficient agreement for clinical decisions and diagnosis. We suggest adjudication of symptom data by patients and physicians, as recommended by the 2010 ACR criteria.
Authors: Giorgia Varallo; Ada Ghiggia; Marco Arreghini; Paolo Capodaglio; Gian Mauro Manzoni; Emanuele Maria Giusti; Lorys Castelli; Gianluca Castelnuovo Journal: Front Psychol Date: 2021-02-09