| Literature DB >> 26413023 |
Wilson W Lam, Meredith A Reyes, John J Seger.
Abstract
We report the case of an 82-year-old man in whom hemorrhagic pericardial effusion occurred one week after pacemaker implantation, while he was taking apixaban. Few therapies exist for reversing the anti-Xa effect of apixaban. To reverse anticoagulation, our patient underwent plasma exchange, which facilitated pericardiocentesis and prevented possible surgical intervention. To our knowledge, this is the first report of the use of plasmapheresis to reverse the anticoagulant effect of apixaban.Entities:
Keywords: Anticoagulants/administration & dosage/adverse effects/antagonists & inhibitors/therapeutic use; apixaban; atrial fibrillation/complications/drug therapy; factor Xa inhibitors; pacemaker, artificial/adverse effects; plasma exchange; risk factors; stroke/prevention & control; treatment outcome; warfarin/therapeutic use
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Year: 2015 PMID: 26413023 PMCID: PMC4567120 DOI: 10.14503/THIJ-14-4424
Source DB: PubMed Journal: Tex Heart Inst J ISSN: 0730-2347