Literature DB >> 26413023

Plasma Exchange for Urgent Apixaban Reversal in a Case of Hemorrhagic Tamponade after Pacemaker Implantation.

Wilson W Lam, Meredith A Reyes, John J Seger.   

Abstract

We report the case of an 82-year-old man in whom hemorrhagic pericardial effusion occurred one week after pacemaker implantation, while he was taking apixaban. Few therapies exist for reversing the anti-Xa effect of apixaban. To reverse anticoagulation, our patient underwent plasma exchange, which facilitated pericardiocentesis and prevented possible surgical intervention. To our knowledge, this is the first report of the use of plasmapheresis to reverse the anticoagulant effect of apixaban.

Entities:  

Keywords:  Anticoagulants/administration & dosage/adverse effects/antagonists & inhibitors/therapeutic use; apixaban; atrial fibrillation/complications/drug therapy; factor Xa inhibitors; pacemaker, artificial/adverse effects; plasma exchange; risk factors; stroke/prevention & control; treatment outcome; warfarin/therapeutic use

Mesh:

Substances:

Year:  2015        PMID: 26413023      PMCID: PMC4567120          DOI: 10.14503/THIJ-14-4424

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  16 in total

Review 1.  Prothrombin complex concentrates: an update.

Authors:  Massimo Franchini; Giuseppe Lippi
Journal:  Blood Transfus       Date:  2010-07       Impact factor: 3.443

Review 2.  Apixaban: a novel oral inhibitor of factor Xa.

Authors:  Edith Nutescu
Journal:  Am J Health Syst Pharm       Date:  2012-07-01       Impact factor: 2.637

3.  Assessment of apixaban plasma levels by laboratory tests: suitability of three anti-Xa assays. A multicentre French GEHT study.

Authors:  Isabelle Gouin-Thibault; Claire Flaujac; Xavier Delavenne; Sara Quenet; Marie-Hélenè Horellou; Silvy Laporte; V Siguret; T Lecompte
Journal:  Thromb Haemost       Date:  2013-10-31       Impact factor: 5.249

4.  Chromogenic laboratory assays to measure the factor Xa-inhibiting properties of apixaban--an oral, direct and selective factor Xa inhibitor.

Authors:  Richard C Becker; Hongqiu Yang; Yuchen Barrett; Puneet Mohan; Jessie Wang; Lars Wallentin; John H Alexander
Journal:  J Thromb Thrombolysis       Date:  2011-08       Impact factor: 2.300

Review 5.  Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: a systematic review and meta-analysis.

Authors:  T van der Hulle; J Kooiman; P L den Exter; O M Dekkers; F A Klok; M V Huisman
Journal:  J Thromb Haemost       Date:  2014       Impact factor: 5.824

6.  Therapeutic plasma exchange: complications and management.

Authors:  M H Mokrzycki; A A Kaplan
Journal:  Am J Kidney Dis       Date:  1994-06       Impact factor: 8.860

7.  European Heart Rhythm Association Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation.

Authors:  Hein Heidbuchel; Peter Verhamme; Marco Alings; Matthias Antz; Werner Hacke; Jonas Oldgren; Peter Sinnaeve; A John Camm; Paulus Kirchhof
Journal:  Europace       Date:  2013-05       Impact factor: 5.214

Review 8.  Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban.

Authors:  Adewale Fawole; Hamed A Daw; Mark A Crowther
Journal:  Cleve Clin J Med       Date:  2013-07       Impact factor: 2.321

Review 9.  Novel thrombin and factor Xa inhibitors: challenges to reversal of their anticoagulation effects.

Authors:  Sean Yates; Ravi Sarode
Journal:  Curr Opin Hematol       Date:  2013-11       Impact factor: 3.284

10.  Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects.

Authors:  Xiaoli Wang; Sabiha Mondal; Jessie Wang; Giridhar Tirucherai; Donglu Zhang; Rebecca A Boyd; Charles Frost
Journal:  Am J Cardiovasc Drugs       Date:  2014-04       Impact factor: 3.571

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  4 in total

1.  Therapeutic Plasma Exchange for Urgent Rivaroxaban Reversal.

Authors:  Varun Kumar; Joseph Allencherril; Arthur Bracey; Alice J Chen; Wilson W Lam
Journal:  Tex Heart Inst J       Date:  2018-04-07

Review 2.  Effects of therapeutic plasma exchange on anticoagulants in patients receiving therapeutic anticoagulation: a systematic review.

Authors:  Kimberly L Hodulik; Adam G Root; Leila S Ledbetter; Oluwatoyosi A Onwuemene
Journal:  Transfusion       Date:  2019-02-14       Impact factor: 3.157

Review 3.  Drug Dosing in Patients Undergoing Therapeutic Plasma Exchange.

Authors:  Sherif Hanafy Mahmoud; Jessica Buhler; Eric Chu; Suzie A Chen; Theresa Human
Journal:  Neurocrit Care       Date:  2021-02       Impact factor: 3.210

4.  Fibrin glue patch for pacemaker lead perforation of the right ventricular free wall: A case report.

Authors:  Satoshi Yamaguchi; Masaki Tabuchi; Kageyuki Oba; Hiroshi Doi; Osamu Arasaki
Journal:  HeartRhythm Case Rep       Date:  2015-11-07
  4 in total

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