Literature DB >> 26412319

Readmission predicts 90-day mortality after esophagectomy: Analysis of Surveillance, Epidemiology, and End Results Registry linked to Medicare outcomes.

Yinin Hu1, Timothy L McMurry2, George J Stukenborg2, Benjamin D Kozower3.   

Abstract

OBJECTIVES: Postoperative readmission is an increasingly scrutinized quality metric that affects patient satisfaction and cost. Even more important is its implication for short-term prognosis. The purpose of this study is to characterize postesophagectomy readmissions and determine their relationship with subsequent 90-day mortality.
METHODS: Data were extracted for esophagectomy patients from the linked SEER-Medicare Registry (2000-2009), which provides longitudinal information about Medicare beneficiaries who have cancer. We assessed demographics, comorbidities, 30-day readmission, and 90-day mortality. Readmitting facility and diagnoses were identified. A hierarchic multivariable regression model clustered at the hospital level assessed the relationship between readmission within 30 days of discharge and 90-day mortality.
RESULTS: We identified 1543 patients discharged alive after esophagectomy. Among patients discharged alive, the readmission rate was 319 of 1543 (20.7%); 107 of 319 (33.5%) readmissions were to facilities that did not perform the index operation. Mortality rate at 90 days among patients discharged alive was 98 of 1543 (6.4%). Readmission was associated with a 4-fold increase in mortality (16.3% vs 3.8%, P < .001). Using multivariable regression, readmission was the strongest predictor of mortality (odds ratio 6.64, P < .001), with a stronger association than age, Charlson score, and index length of stay. Readmission diagnoses with the highest mortality rates were those associated with pulmonary, gastrointestinal, and cardiovascular diagnoses.
CONCLUSIONS: Patients readmitted within 30 days of discharge after esophagectomy are at exceptionally high risk for early mortality. Early recognition of life-threatening readmission diagnoses is essential to providing optimal care.
Copyright © 2015 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  esophageal cancer; esophagectomy; outcomes; postoperative mortality; postoperative readmission

Mesh:

Year:  2015        PMID: 26412319      PMCID: PMC4637190          DOI: 10.1016/j.jtcvs.2015.08.071

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  33 in total

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Journal:  World J Surg       Date:  2015-02       Impact factor: 3.352

2.  Understanding mortality as a quality indicator after esophagectomy.

Authors:  Dustin M Walters; Timothy L McMurry; James M Isbell; George J Stukenborg; Benjamin D Kozower
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3.  Efficacy of early postoperative enteral nutrition in supporting patients after esophagectomy.

Authors:  Y Xiao-Bo; L Qiang; Q Xiong; R Zheng; Z Jian; Z Jian-Hua; Z Qian-Jun
Journal:  Minerva Chir       Date:  2014-02-07       Impact factor: 1.000

4.  Outcomes, quality of life, and survival after esophagectomy for squamous cell carcinoma: A propensity score-matched comparison of operative approaches.

Authors:  Hao Wang; Yaxing Shen; Mingxiang Feng; Yi Zhang; Wei Jiang; Songtao Xu; Lijie Tan; Qun Wang
Journal:  J Thorac Cardiovasc Surg       Date:  2015-01-09       Impact factor: 5.209

5.  Major post-operative complications predict long-term survival after esophagectomy in patients with adenocarcinoma of the esophagus.

Authors:  Guillaume Luc; Marlène Durand; Laurence Chiche; Denis Collet
Journal:  World J Surg       Date:  2015-01       Impact factor: 3.352

6.  Postoperative mortality is an inadequate quality indicator for lung cancer resection.

Authors:  Yinin Hu; Timothy L McMurry; Kristen M Wells; James M Isbell; George J Stukenborg; Benjamin D Kozower
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7.  Hospital readmission is associated with poor survival after esophagectomy for esophageal cancer.

Authors:  Felix G Fernandez; Onkar Khullar; Seth D Force; Renjian Jiang; Allan Pickens; David Howard; Kevin Ward; Theresa Gillespie
Journal:  Ann Thorac Surg       Date:  2014-11-11       Impact factor: 4.330

8.  Impact of a Fast-track Esophagectomy Protocol on Esophageal Cancer Patient Outcomes and Hospital Charges.

Authors:  Jitesh B Shewale; Arlene M Correa; Carla M Baker; Nicole Villafane-Ferriol; Wayne L Hofstetter; Victoria S Jordan; Henrik Kehlet; Katie M Lewis; Reza J Mehran; Barbara L Summers; Diane Schaub; Sonia A Wilks; Stephen G Swisher
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9.  Readmission after lung cancer resection is associated with a 6-fold increase in 90-day postoperative mortality.

Authors:  Yinin Hu; Timothy L McMurry; James M Isbell; George J Stukenborg; Benjamin D Kozower
Journal:  J Thorac Cardiovasc Surg       Date:  2014-04-18       Impact factor: 5.209

Review 10.  Enhanced recovery pathways lead to an improvement in postoperative outcomes following esophagectomy: systematic review and pooled analysis.

Authors:  S R Markar; A Karthikesalingam; D E Low
Journal:  Dis Esophagus       Date:  2014-04-03       Impact factor: 3.429

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2.  Short-term and intermediate-term readmission after esophagectomy.

Authors:  Yoyo Wang; Chi-Fu Jeffrey Yang; Hao He; Josephine M Buchan; Deven C Patel; Douglas Z Liou; Natalie S Lui; Mark F Berry; Joseph B Shrager; Leah M Backhus
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3.  Mortality and Graft Loss Attributable to Readmission After Kidney Transplantation: Immediate and Long-term Risk.

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4.  Incidence and risk factors of readmission after esophagectomy for esophageal cancer.

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Journal:  J Thorac Dis       Date:  2019-11       Impact factor: 2.895

5.  Spontaneous regionalization of esophageal cancer surgery: an analysis of the National Cancer Database.

Authors:  Brian N Arnold; Alexander S Chiu; Jessica R Hoag; Clara H Kim; Michelle C Salazar; Justin D Blasberg; Daniel J Boffa
Journal:  J Thorac Dis       Date:  2018-03       Impact factor: 2.895

6.  Commentary: Surgical risk assessment in 2020: Is a handshake and a walking test really the best we've got?

Authors:  Ernest G Chan; Chigozirim N Ekeke; James D Luketich
Journal:  J Thorac Cardiovasc Surg       Date:  2020-11-20       Impact factor: 5.209

7.  Readmission after esophageal resection for esophageal cancer: incidence and risk factors.

Authors:  Saurabh Singhal; Sumeet K Mittal
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8.  The Impact of Hospital Size on National Trends and Outcomes Following Open Esophagectomy.

Authors:  Sameer A Hirji; Rohan M Shah; Adam Fields; Vwaire Orhurhu; Nizar Bhulani; Abby White; Gita N Mody; Scott J Swanson
Journal:  Medicina (Kaunas)       Date:  2019-10-03       Impact factor: 2.430

9.  Early Readmissions after Esophagectomy for Esophageal Adenocarcinoma: Does Facility Case-Volume Matter?

Authors:  Kwabena Oware Adu-Gyamfi; Chaitanya Pant; Abhishek Deshpande; Hassanain Jassim; Mojtaba Olyaee
Journal:  Surg Res Pract       Date:  2020-01-28

10.  Readmissions With Multidrug-Resistant Infection in Patients With Prior Multidrug Resistant Infection.

Authors:  Jason P Burnham; Jennie H Kwon; Margaret A Olsen; Hilary M Babcock; Marin H Kollef
Journal:  Infect Control Hosp Epidemiol       Date:  2017-12-17       Impact factor: 3.254

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