Literature DB >> 26409932

What do animal experiments tell us that in vitro systems cannot? The Human Toxome Project.

Daniel W Nebert1, Magnus Ingelman-Sundberg2.   

Abstract

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Keywords:  Cell culture studies; Human Toxome Project; Human vs mouse PPARA; Intact animal studies; In vitro studies; Mouse genetics; Toxicity and cancer by fibrate drugs; Toxicity and cancer by oral benzo[a]pyrene

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Year:  2015        PMID： 26409932     DOI： 10.1016/j.yrtph.2015.09.027

Source DB:  PubMed          Journal:  Regul Toxicol Pharmacol        ISSN： 0273-2300            Impact factor:   3.271


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  2 in total

Review 1.  From Classical Toxicology to Tox21: Some Critical Conceptual and Technological Advances in the Molecular Understanding of the Toxic Response Beginning From the Last Quarter of the 20th Century.

Authors:  Supratim Choudhuri; Geoffrey W Patton; Ronald F Chanderbhan; Antonia Mattia; Curtis D Klaassen
Journal:  Toxicol Sci       Date:  2018-01-01       Impact factor: 4.849

Review 2.  Translating Neurobehavioral Toxicity Across Species From Zebrafish to Rats to Humans: Implications for Risk Assessment.

Authors:  Charles V Vorhees; Michael T Williams; Andrew B Hawkey; Edward D Levin
Journal:  Front Toxicol       Date:  2021-02-23
  2 in total

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