Literature DB >> 26408167

Endocannabinoids and Reproductive Events in Health and Disease.

Natalia Battista1, Monica Bari2,3, Mauro Maccarrone4,5.   

Abstract

The lasting research on the endocannabinoid system (ECS) has now provided solid and convincing evidence that proves the detrimental effects of recreational drug abuse (a growing habit among teenagers) on fertility. Endocannabinoids (eCBs) affect reproductive events from gametogenesis to fertilization, from embryo implantation to the final outcome of pregnancy and, thus, they have been proposed as suitable biomarkers to predict the reproductive potential of male and female gametes in clinical practice. Novel tools for reproductive medicine are highly sought after, and here we report the latest findings on the impact of the ECS on fertility, demonstrating how basic research can be translated into new medical strategies.

Entities:  

Keywords:  AEA Anandamide; Biomarkers; Endocannabinoid system; Infertility; Reproduction

Mesh：

Substances：

Year:  2015        PMID： 26408167     DOI： 10.1007/978-3-319-20825-1_12

Source DB:  PubMed          Journal:  Handb Exp Pharmacol        ISSN： 0171-2004


  7 in total

1.  Proteomic profile of maternal-aged blastocoel fluid suggests a novel role for ubiquitin system in blastocyst quality.

Authors:  Gabriella Tedeschi; Elena Albani; Elena Monica Borroni; Valentina Parini; Anna Maria Brucculeri; Elisa Maffioli; Armando Negri; Simona Nonnis; Mauro Maccarrone; Paolo Emanuele Levi-Setti
Journal:  J Assist Reprod Genet       Date:  2016-12-06       Impact factor: 3.412

Review 2.  Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.

Authors:  David R Janero; Ganesh A Thakur
Journal:  Expert Opin Drug Discov       Date:  2016-10-21       Impact factor: 6.098

3.  Mitochondrial Localization of CB1 in Progesterone-producing Cells of Ovarian Interstitial Glands of Adult Mice.

Authors:  Anussara Kamnate; Juthathip Sirisin; Masahiko Watanabe; Hisatake Kondo; Wiphawi Hipkaeo; Surang Chomphoo
Journal:  J Histochem Cytochem       Date:  2021-12-17       Impact factor: 2.479

4.  Cannabis significantly alters DNA methylation of the human ovarian follicle in a concentration-dependent manner.

Authors:  Noga Fuchs Weizman; Brandon A Wyse; Janice Montbriand; Sahar Jahangiri; Clifford L Librach
Journal:  Mol Hum Reprod       Date:  2022-06-08       Impact factor: 4.518

5.  The correlation of anandamide with gonadotrophin and sex steroid hormones during the menstrual cycle.

Authors:  Na Cui; Luning Wang; Wei Wang; Jie Zhang; Yueming Xu; Lei Jiang; Guimin Hao
Journal:  Iran J Basic Med Sci       Date:  2017-11       Impact factor: 2.699

6.  Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice.

Authors:  Emmanuel Dotsey; Irina Ushach; Egest Pone; Rie Nakajima; Algis Jasinskas; Donovan A Argueta; Andrea Dillon; Nicholas DiPatrizio; Huw Davies; Albert Zlotnik; Peter D Crompton; Philip L Felgner
Journal:  Sci Rep       Date:  2017-02-17       Impact factor: 4.379

7.  The Roles of Anandamide, Fatty Acid Amide Hydrolase, and Leukemia Inhibitory Factor on the Endometrium during the Implantation Window.

Authors:  Na Cui; Changyan Wang; Zhiming Zhao; Jie Zhang; Yueming Xu; Yang Yang; Guimin Hao
Journal:  Front Endocrinol (Lausanne)       Date:  2017-10-16       Impact factor: 5.555
  7 in total

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