Literature DB >> 26405151

NUDT15 c.415C>T increases risk of 6-mercaptopurine induced myelosuppression during maintenance therapy in children with acute lymphoblastic leukemia.

Kanhatai Chiengthong1, Chupong Ittiwut2, Sasipa Muensri2, Jiratchaya Sophonphan3, Darintr Sosothikul1, Panya Seksan1, Koramit Suppipat4, Kanya Suphapeetiporn5, Vorasuk Shotelersuk5.   

Abstract

Entities:  

Keywords:  NUDT15; acute lymphoblastic leukemia; myelosuppression; pharmacogenetics

Mesh:

Substances:

Year:  2015        PMID: 26405151      PMCID: PMC4697903          DOI: 10.3324/haematol.2015.134775

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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  15 in total

1.  Chemotherapy of acute lymphocytic leukemia of childhood.

Authors:  J F Holland; O Glidewell
Journal:  Cancer       Date:  1972-12       Impact factor: 6.860

2.  The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children.

Authors:  Yoichi Tanaka; Atsushi Manabe; Hisaya Nakadate; Kensuke Kondoh; Kozue Nakamura; Katsuyoshi Koh; Tomoyuki Utano; Akira Kikuchi; Takako Komiyama
Journal:  Leuk Res       Date:  2011-12-24       Impact factor: 3.156

3.  Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia.

Authors:  M V Relling; M L Hancock; J M Boyett; C H Pui; W E Evans
Journal:  Blood       Date:  1999-05-01       Impact factor: 22.113

4.  The treatment of acute lymphoblastic leukaemia.

Authors:  J V Simone
Journal:  Br J Haematol       Date:  1980-05       Impact factor: 6.998

5.  Molecular analysis of thiopurine S-methyltransferase alleles in South-east Asian populations.

Authors:  Jan-Gowth Chang; Long-Shyong Lee; Chih-Mei Chen; Mu-Chin Shih; Mei-Chen Wu; Fuu-Jen Tsai; Der-Cheng Liang
Journal:  Pharmacogenetics       Date:  2002-04

6.  Polymorphism of ITPA 94C>A and risk of adverse effects among patients with acute lymphoblastic leukaemia treated with 6-mercaptopurine.

Authors:  W R Wan Rosalina; L K Teh; N Mohamad; A Nasir; R Yusoff; A A Baba; M Z Salleh
Journal:  J Clin Pharm Ther       Date:  2011-05-05       Impact factor: 2.512

Review 7.  Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia.

Authors:  Stephen P Hunger; Mignon L Loh; James A Whitlock; Naomi J Winick; William L Carroll; Meenakshi Devidas; Elizabeth A Raetz
Journal:  Pediatr Blood Cancer       Date:  2012-12-19       Impact factor: 3.167

8.  Impact of the heterozygous TPMT*1/*3C genotype on azathioprine-induced myelosuppression in kidney transplant recipients in Thailand.

Authors:  Suda Vannaprasaht; Susothorn Angsuthum; Yingyos Avihingsanon; Dhavee Sirivongs; Cholatip Pongskul; Pattarapong Makarawate; Kearkiat Praditpornsilpa; Wongwiwat Tassaneeyakul; Wichittra Tassaneeyakul
Journal:  Clin Ther       Date:  2009-07       Impact factor: 3.393

9.  Implementation of TPMT testing.

Authors:  Lynne Lennard
Journal:  Br J Clin Pharmacol       Date:  2014-04       Impact factor: 4.335

10.  Thiopurine S-methyltransferase genetic polymorphism in the Thai population.

Authors:  Somrudee Srimartpirom; Wongwiwat Tassaneeyakul; Veerapol Kukongviriyapan; Wichittra Tassaneeyakul
Journal:  Br J Clin Pharmacol       Date:  2004-07       Impact factor: 4.335

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  35 in total

1.  DNA-thioguanine nucleotide as a treatment marker in acute lymphoblastic leukemia patients with NUDT15 variant genotypes.

Authors:  Hee Young Ju; Ji Won Lee; Hee Won Cho; Ju Kyung Hyun; Youngeun Ma; Eun Sang Yi; Keon Hee Yoo; Ki Woong Sung; Rihwa Choi; Hong Hoe Koo; Soo-Youn Lee
Journal:  PLoS One       Date:  2021-01-22       Impact factor: 3.240

Review 2.  Pharmacogenetic Predictors of Treatment-Related Toxicity Among Children With Acute Lymphoblastic Leukemia.

Authors:  Rochelle R Maxwell; Peter D Cole
Journal:  Curr Hematol Malig Rep       Date:  2017-06       Impact factor: 3.952

3.  Pathway genes and metabolites in thiopurine therapy in Korean children with acute lymphoblastic leukaemia.

Authors:  Rihwa Choi; Insuk Sohn; Min-Ji Kim; Hye In Woo; Ji Won Lee; Youngeun Ma; Eun Sang Yi; Hong Hoe Koo; Soo-Youn Lee
Journal:  Br J Clin Pharmacol       Date:  2019-05-27       Impact factor: 4.335

4.  Combination of common and novel rare NUDT15 variants improves predictive sensitivity of thiopurine-induced leukopenia in children with acute lymphoblastic leukemia.

Authors:  Yiping Zhu; Dandan Yin; Yali Su; Xuyang Xia; Takaya Moriyama; Rina Nishii; Fei Liao; Shouyue Zhang; Xia Guo; Qianqian Hou; Yuan Ai; Xueyan Zhou; Shuwen Sun; Duyu Zhang; Yan Zhang; Chao Lin; Yiqi Deng; Xiaoxi Lu; Yuelan Wang; Zhigui Ma; Heyao Wang; Bo Liu; Li Yang; Wei Zhang; Jun J Yang; Yang Shu; Ju Gao; Heng Xu
Journal:  Haematologica       Date:  2018-03-08       Impact factor: 9.941

Review 5.  Association of NUDT15 c.415C>T allele and thiopurine-induced leukocytopenia in Asians: a systematic review and meta-analysis.

Authors:  A L Zhang; J Yang; H Wang; J L Lu; S Tang; X J Zhang
Journal:  Ir J Med Sci       Date:  2017-05-03       Impact factor: 1.568

6.  NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.

Authors:  Nicholas C K Valerie; Anna Hagenkort; Brent D G Page; Geoffrey Masuyer; Daniel Rehling; Megan Carter; Luka Bevc; Patrick Herr; Evert Homan; Nina G Sheppard; Pål Stenmark; Ann-Sofie Jemth; Thomas Helleday
Journal:  Cancer Res       Date:  2016-08-16       Impact factor: 12.701

7.  Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry.

Authors:  Takaya Moriyama; Yung-Li Yang; Rina Nishii; Hany Ariffin; Chengcheng Liu; Ting-Nien Lin; Wenjian Yang; Dong-Tsamn Lin; Chih-Hsiang Yu; Shirley Kham; Ching-Hon Pui; William E Evans; Sima Jeha; Mary V Relling; Allen Eng-Juh Yeoh; Jun J Yang
Journal:  Blood       Date:  2017-06-28       Impact factor: 22.113

8.  Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia.

Authors:  Y Tanaka; H Nakadate; K Kondoh; K Nakamura; K Koh; A Manabe
Journal:  Pharmacogenomics J       Date:  2017-04-18       Impact factor: 3.550

Review 9.  [Research advances in pharmacogenomics of mercaptopurine].

Authors:  Xiao-Xiao Chen; Shu-Hong Shen
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2017-09

10.  Childhood acute lymphoblastic leukemia mercaptopurine intolerance is associated with NUDT15 variants.

Authors:  Der-Shiun Wang; Chih-Hsiang Yu; Chien-Yu Lin; Ya-Hsuan Chang; Kai-Hsin Lin; Dong-Tsamn Lin; Shiann-Tarng Jou; Meng-Yao Lu; Hsiu-Hao Chang; Shu-Wha Lin; Hsuan-Yu Chen; Yung-Li Yang
Journal:  Pediatr Res       Date:  2020-03-27       Impact factor: 3.756

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