| Literature DB >> 26403145 |
Axel Van Der Gucht1,2,3,4,5, Arnault Galat6,7,8,9,10, Jean Rosso6,7,8,11, Aziz Guellich6,7,8,9,10, Jérôme Garot12, Diane Bodez6,7,8,9,10, Violaine Plante-Bordeneuve6,7,8,9,13, Luc Hittinger6,7,8,9,10, Jean-Luc Dubois-Randé6,7,8,9,10, Eva Evangelista6,8,11, Myriam Sasanelli6,8,11, Julia Chalaye6,8,11, Michel Meignan6,7,8,11, Emmanuel Itti6,7,8,11,9, Thibaud Damy6,7,8,9,10.
Abstract
Cardiac amyloidosis (CA) is recognized as a common cause of restrictive cardiomyopathy and heart failure due to the deposition of insoluble proteins in the myocardial interstitium. We emphasize the role of [18F]-sodium fluoride (NaF) PET/CT as a potential noninvasive tool to identify and differentiate the transthyretin-related cardiac amyloidosis from the light-chain cardiac amyloidosis. We report cases of a 73-year-old man and a 75-year-old woman followed in our center for congestive heart failure with marked alteration of the left ventricular ejection fraction due to familial transthyretin Val122Ile cardiac amyloidosis and light-chain cardiac amyloidosis, respectively, confirmed on endomyocardial biopsy.Entities:
Keywords: PET/CT; [18F]-NaF; cardiac amyloidosis; protein deposition
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Year: 2015 PMID: 26403145 DOI: 10.1007/s12350-015-0287-0
Source DB: PubMed Journal: J Nucl Cardiol ISSN: 1071-3581 Impact factor: 5.952