Literature DB >> 26401110

Laparoscopy versus laparotomy for the management of endometrial carcinoma in morbidly obese patients: a prospective study.

Özgür Bige1, Ahmet Demir2, Bahadır Saatli3, Meral Koyuncuoğlu4, Uğur Saygılı3.   

Abstract

OBJECTIVE: To compare the results of total laparoscopic hysterectomy and total abdominal hysterectomy in morbidly obese women with early stage endometrial cancer.
MATERIAL AND METHODS: This prospective study was conducted on 140 morbidly obese women with body mass indices ≥35 kg/m(2) and presenting with clinical stage 1 endometrial cancer. The patients underwent total laparoscopic hysterectomy (n=70) or total abdominal hysterectomy (n=70), bilateral salpingo-oophorectomy, pelvic lymphadenectomy, and peritoneal washing. Age, parity, menopausal status, weight, height, medical problems, history of previous laparotomy, surgical procedure, operative time, estimated amount of blood loss, preoperative hematocrit, postoperative hematocrit, operative complications, conversion to laparotomy, need for intraoperative or postoperative blood transfusion, intraoperative and postoperative complications, secondary surgery, tumor stage, grade, histology, number of recovered lymph nodes, and visual pain scores of the patients were recorded.
RESULTS: Postoperative complications were significantly higher in the laparotomy group. Hospital stay in the laparoscopy group was significantly lower than that in the laparotomy group. The visual pain scores were significantly higher in the laparotomy group on the first, second, and third postoperative days and on the day of discharge from the hospital. Resuming activity took a significantly longer time in the laparotomy group (34.70 days) than in the laparoscopic group (17.89 days).
CONCLUSION: With the availability of skilled endoscopic surgeons, most obese women with early stage endometrial cancer can be safely managed by performing laparoscopy with an excellent surgical outcome, shorter hospitalization, less postoperative pain, and faster resumption of full activity.

Entities:  

Keywords:  Laparoscopy; endometrial carcinoma; morbidly obese patients

Year:  2015        PMID: 26401110      PMCID: PMC4560474          DOI: 10.5152/jtgga.2015.15128

Source DB:  PubMed          Journal:  J Turk Ger Gynecol Assoc        ISSN: 1309-0380


  25 in total

1.  Weight change and risk of endometrial cancer.

Authors:  A Trentham-Dietz; H B Nichols; J M Hampton; P A Newcomb
Journal:  Int J Epidemiol       Date:  2005-11-08       Impact factor: 7.196

2.  [Endometrial cancer by laparoscopy and vaginal approach in the obese patient].

Authors:  Frédéric Caquant; Marie Mas-Calvet; Caroline Turbelin; Anne Lesoin; Daniele Lefebvre; Fabrice Narducci; Denis Querleu; Eric Leblanc
Journal:  Bull Cancer       Date:  2006-04       Impact factor: 1.276

3.  Determinants of lymph node count in endometrial cancer surgical staging.

Authors:  Beatrice Cormier; Philippe Sauthier; Christian Lussier; Geng Zang; Marie-Helene Mayrand
Journal:  Int J Gynecol Cancer       Date:  2012-10       Impact factor: 3.437

4.  Total laparoscopic hysterectomy in the management of endometrial carcinoma.

Authors:  Tom P Manolitsas; Anthony J McCartney
Journal:  J Am Assoc Gynecol Laparosc       Date:  2002-02

5.  Laparoscopic pelvic and paraaortic lymph node dissection in the obese.

Authors:  Dennis R Scribner; Joan L Walker; Gary A Johnson; D Scott McMeekin; Michael A Gold; Robert S Mannel
Journal:  Gynecol Oncol       Date:  2002-03       Impact factor: 5.482

6.  Obesity in relation to endometrial cancer risk and disease characteristics in the Women's Health Initiative.

Authors:  Katherine W Reeves; Gebra Cuyun Carter; Rebecca J Rodabough; Dorothy Lane; S Gene McNeeley; Marcia L Stefanick; Electra D Paskett
Journal:  Gynecol Oncol       Date:  2011-02-15       Impact factor: 5.482

7.  Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.

Authors:  Eugenia E Calle; Carmen Rodriguez; Kimberly Walker-Thurmond; Michael J Thun
Journal:  N Engl J Med       Date:  2003-04-24       Impact factor: 91.245

8.  What is the optimal minimally invasive surgical procedure for endometrial cancer staging in the obese and morbidly obese woman?

Authors:  Paola A Gehrig; Leigh A Cantrell; Aaron Shafer; Lisa N Abaid; Alberto Mendivil; John F Boggess
Journal:  Gynecol Oncol       Date:  2008-08-09       Impact factor: 5.482

9.  Laparoscopy or laparotomy? A comparison of 240 patients with early-stage endometrial cancer.

Authors:  Alessandro Santi; Annette Kuhn; Thomas Gyr; Markus Eberhard; Silke Johann; Andreas R Günthert; Michael D Mueller
Journal:  Surg Endosc       Date:  2009-06-16       Impact factor: 4.584

10.  Laparoscopic surgery for endometrial cancer: increasing body mass index does not impact postoperative complications.

Authors:  C William Helm; Cibi Arumugam; Mary E Gordinier; Daniel S Metzinger; Jianmin Pan; Shesh N Rai
Journal:  J Gynecol Oncol       Date:  2011-09-28       Impact factor: 4.401

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  3 in total

1.  ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma.

Authors:  Nicole Concin; Carien L Creutzberg; Ignace Vergote; David Cibula; Mansoor Raza Mirza; Simone Marnitz; Jonathan A Ledermann; Tjalling Bosse; Cyrus Chargari; Anna Fagotti; Christina Fotopoulou; Antonio González-Martín; Sigurd F Lax; Domenica Lorusso; Christian Marth; Philippe Morice; Remi A Nout; Dearbhaile E O'Donnell; Denis Querleu; Maria Rosaria Raspollini; Jalid Sehouli; Alina E Sturdza; Alexandra Taylor; Anneke M Westermann; Pauline Wimberger; Nicoletta Colombo; François Planchamp; Xavier Matias-Guiu
Journal:  Virchows Arch       Date:  2021-02       Impact factor: 4.064

2.  Comparison of Laparoscopy and Laparotomy in Early-Stage Endometrial Cancer: Early Experiences from a Developing Country.

Authors:  Yusuf Cakmak; Duygu Kavak Comert; Isik Sozen; Tufan Oge
Journal:  J Oncol       Date:  2020-04-30       Impact factor: 4.375

3.  Exploring the role of obesity and overweight in predicting postoperative outcome of abdominal surgery in a sub-Saharan African setting: a prospective cohort study.

Authors:  Benjamin Momo Kadia; Alain Chichom-Mefire; Gregory Edie Halle-Ekane
Journal:  BMC Res Notes       Date:  2018-10-19
  3 in total

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