Türker Emre1, Özgür Kiliçkesmez2, Atılay Büker3, Berrin Berçik İnal4, Hüseyin Doğan5, Tevfik Ecder6. 1. Department of Nephrology, Istanbul Research and Training Hospital, Istanbul, Turkey. aturkeremre@yahoo.com.tr. 2. Department of Radyology, Istanbul Research and Training Hospital, Istanbul, Turkey. okilickesmez@yahoo.com. 3. Department of Radyology, Istanbul Research and Training Hospital, Istanbul, Turkey. atilaybuker@gmail.com. 4. Department of Biochemistry, Istanbul Research and Training Hospital, Istanbul, Turkey. berrin_inal@yahoo.com. 5. Fatih Private Hemodialysis Unite, Istanbul, Turkey. huseyindogan@yahoo.com. 6. Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Istanbul University, Fatih, Istanbul, Turkey. tevfikecder@yahoo.com.
Abstract
AIM: To diagnose earlier kidney failure, we investigated renal functions with diffusion-weighted imaging (DWI). METHODS: We evaluated the DWI of 62 patients with chronic kidney disease (CKD) and compared it with creatinine clearance provided by daily urine collection. The apparent diffusion coefficient (ADC) values were compared with the five stages of CKD. RESULTS: For each stage of CKD, the ADC values were found to be significantly different (p < 0.01) and allowed the differentiation of stage 1 of the disease from the other stages. CONCLUSION: Renal ADC values show a significant correlation with the clinical stages of CKD. DWI may detect renal failure prior to a rise in creatinine.
AIM: To diagnose earlier kidney failure, we investigated renal functions with diffusion-weighted imaging (DWI). METHODS: We evaluated the DWI of 62 patients with chronic kidney disease (CKD) and compared it with creatinine clearance provided by daily urine collection. The apparent diffusion coefficient (ADC) values were compared with the five stages of CKD. RESULTS: For each stage of CKD, the ADC values were found to be significantly different (p < 0.01) and allowed the differentiation of stage 1 of the disease from the other stages. CONCLUSION: Renal ADC values show a significant correlation with the clinical stages of CKD. DWI may detect renal failure prior to a rise in creatinine.
Entities:
Keywords:
Diffusion-weighted imaging; Kidney failure; Renal function
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