Literature DB >> 26388124

Delayed primary closure and the incidence of surgical complications in pediatric liver transplant recipients.

William A Ziaziaris1, Alexandre Darani2, Andrew J A Holland3, Angus Alexander2, Jonathan Karpelowsky1, Albert Shun3, Gordon Thomas4.   

Abstract

PURPOSE: The purpose of this study was to analyze the general surgical complications in pediatric liver transplant recipients and the safety of delayed primary closure at a single tertiary center.
METHODS: A retrospective review of all liver transplant recipients between April 1986 and May 2014 was performed. All general and gastrointestinal complications were recorded and analyzed. The incidence and risk of these complications were compared between children who had a primary versus those who had a delayed closure, with or without the use of Surgisis®, of their abdomen.
RESULTS: 242 patients underwent 281 liver transplants. The median age of the children was 31months. Whole (77), reduced size (91), split (96), and living related grafts (17) were used. General surgical complications were observed in 33 cases (11.7%). 135 cases underwent delayed primary closure (DPC) of their abdomen, 35 with Surgisis®. Patients with biliary atresia had a higher rate (4.6%) of bowel perforation (p=0.013). The majority of complications occurred within 3months of transplantation.
CONCLUSION: General surgical complications postpediatric liver transplantation were common but usually not life threatening. Delayed primary closure was safe, had no significant long-term issues, and was not associated with higher incidence of wound related complications. Crown
Copyright © 2015. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Biliary atresia; Delayed primary closure; Gastrointestinal complications; General surgical complications; Liver transplantation; Pediatric

Mesh:

Year:  2015        PMID: 26388124     DOI: 10.1016/j.jpedsurg.2015.08.045

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  2 in total

1.  Pediatric living donor liver transplantation (LDLT): Short- and long-term outcomes during sixteen years period at a single centre- A retrospective cohort study.

Authors:  Emad Hamdy Gad; Ahmed Nabil Sallam; Hosam Soliman; Tarek Ibrahim; Tahany Abdel Hameed Salem; Mohammed Abdel-Hafez Ali; Mohammed Al-Sayed Abd-Same; Islam Ayoub
Journal:  Ann Med Surg (Lond)       Date:  2022-06-07

2.  Growth of liver allografts over time in pediatric transplant recipients.

Authors:  S G Chaudhry; S Bentley-Hibbert; J Stern; S Lobritto; M Martinez; J Vittorio; K J Halazun; H T Lee; J Emond; T Kato; B Samstein; A Griesemer
Journal:  Pediatr Transplant       Date:  2018-01-15
  2 in total

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