Literature DB >> 26386847

Melanotic schwannoma: an 11-year case series.

Michael Khoo1, Ian Pressney2, Rikin Hargunani2, Roberto Tirabosco3.   

Abstract

Melanotic or melanocytic schwannoma is a rare tumour usually involving spinal nerve roots but can also present at other anatomical locations. Although there are less than 200 cases reported, melanotic schwannomas can have distinctive imaging features but there is limited recent literature on its often characteristic radiological appearances. Recent publication of the largest case series thus far has suggested melanotic schwannoma to be a separate entity to other schwannomata and that its reclassification to a malignant lesion be under consideration. We present a case series over an 11-year period to highlight salient imaging features with reference to the current concerns regarding its malignant potential.

Entities:  

Keywords:  Carney complex; Malignant potential; Melanin; Melanotic schwannoma; Peripheral nerve sheath tumour; Psammomatous melanotic schwannoma; Sarcoma; Schwannoma

Mesh:

Year:  2015        PMID: 26386847     DOI: 10.1007/s00256-015-2256-8

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  13 in total

1.  Magnetic resonance imaging of intraspinal melanotic schwannoma.

Authors:  M Bendszus; H Urbach; H K Wolf; J Schramm; L Solymosi
Journal:  Eur Radiol       Date:  1998       Impact factor: 5.315

2.  Spinal melanotic schwannoma: a tumour with poor prognosis.

Authors:  A V Vallat-Decouvelaere; M Wassef; G Lot; M Catala; M Moussalam; N Caruel; J Mikol
Journal:  Histopathology       Date:  1999-12       Impact factor: 5.087

3.  CT and MR imaging of melanocytic schwannomas; report of three cases.

Authors:  G Liessi; R Barbazza; F Sartori; P Sabbadin; A Scapinello
Journal:  Eur J Radiol       Date:  1990 Sep-Oct       Impact factor: 3.528

4.  Dumbbell-shaped nonpsammomatous malignant melanotic schwannoma of the cervical spinal root.

Authors:  Hajime Yokota; Koichi Isobe; Masazumi Murakami; Hitoshi Kubosawa; Takashi Uno
Journal:  Spine J       Date:  2012-04-19       Impact factor: 4.166

5.  Intracranial and spinal melanotic schwannoma in the same patient.

Authors:  Ralf Buhl; Harald Barth; Heinz H Hugo; Victor F Mautner; H Maximilian Mehdorn
Journal:  J Neurooncol       Date:  2004-07       Impact factor: 4.130

6.  Multiple melanotic schwannoma.

Authors:  Nil Culhaci; Emel Dikicioĝlu; Ibrahim Meteoğlu; Sükrü Boylu
Journal:  Ann Diagn Pathol       Date:  2003-08       Impact factor: 2.090

7.  Melanotic schwannoma of the pancreas: report of a case.

Authors:  Takashi Akiyoshi; Yuji Ueda; Kohsuke Yanai; Hiroshi Yamaguchi; Masahiko Kawamoto; Kiyokazu Toyoda; Tohru Hayashi; Jiro Ohuchida
Journal:  Surg Today       Date:  2004       Impact factor: 2.549

8.  Psammomatous melanotic schwannoma. A distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome.

Authors:  J A Carney
Journal:  Am J Surg Pathol       Date:  1990-03       Impact factor: 6.394

9.  Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic schwannoma".

Authors:  Jorge Torres-Mora; Sarah Dry; Xinmin Li; Scott Binder; Mitual Amin; Andrew L Folpe
Journal:  Am J Surg Pathol       Date:  2014-01       Impact factor: 6.394

Review 10.  Dorsal dumb-bell melanotic schwannoma operated on by posterior and anterior approach: case report and a review of the literature.

Authors:  Leonardo De Cerchio; Filiberto Contratti; Mario F Fraioli
Journal:  Eur Spine J       Date:  2006-09-01       Impact factor: 3.134

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  9 in total

1.  Extramedullary malignant melanotic schwannoma of the spine: Case report and an up to date systematic review of the literature.

Authors:  Georgios Solomou; Adikarige Haritha Dulanka Silva; Adrianna Wong; Ute Pohl; Nikolaos Tzerakis
Journal:  Ann Med Surg (Lond)       Date:  2020-10-07

2.  Novel response to neoadjuvant anti-PD1 therapy for a patient with retrocaval melanotic schwannoma.

Authors:  Charles C Vining; Phillip J Hsu; Aaron Miller; Daniel J Olson; Thomas F Gajewski; Peter Pytel; Bruce S Bauer; Michael J Millis; Kevin K Roggin
Journal:  Melanoma Res       Date:  2021-02-01       Impact factor: 3.199

3.  Rexin-G®, a tumor-targeted retrovector for malignant peripheral nerve sheath tumor: A case report.

Authors:  Seth Kim; Noah Federman; Erlinda M Gordon; Frederick L Hall; Sant P Chawla
Journal:  Mol Clin Oncol       Date:  2017-04-28

4.  A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male.

Authors:  Sung-Eun Choi; Yoon Jin Cha; Jisup Kim; Hyunseo Cha; Jayeong Seo; Sung-Uk Kuh; Sung-Jun Kim; Se Hoon Kim
Journal:  J Pathol Transl Med       Date:  2017-04-04

5.  A Rare Case of Intraspinal Psammomatous Melanotic Schwannoma: A Case Report.

Authors:  Naoki Takatori; Akihiko Hiyama; Daisuke Sakai; Hiroyuki Katoh; Masato Sato; Masahiko Watanabe
Journal:  Spine Surg Relat Res       Date:  2019-07-10

6.  Hemorrhagic spinal melanotic schwannoma presenting as acute chest pain: A case report and literature review.

Authors:  Dallas J Soyland; Dylan R Goehner; Kayla M Hoerschgen; Troy D Gust; Shawn M Vuong
Journal:  Surg Neurol Int       Date:  2021-04-14

7.  Malignant psammomatous melanotic schwannoma mimicking adrenal cyst: case report.

Authors:  Aleksandar Zlatarov; Plamena Drenakova; Stefan Mihaylov; Neli Zgurova; Lilyana Petkova; Krasimir D Ivanov
Journal:  Ann Pediatr Surg       Date:  2022-07-07

Review 8.  A para-aortic malignant melanotic nerve sheath tumor mimicking a gastrointestinal stromal tumor: a rare case report and review of literature.

Authors:  Kuan-Yu Lin; Lujen Chen; Chih-Jung Chen; Kun-Yuan Chiu; Siu-Wan Hung; Sheng-Chun Hung; Cheng-Kuang Yang
Journal:  BMC Surg       Date:  2022-07-28       Impact factor: 2.030

9.  Can Discord Domain-Containing Receptor 2 Mutation Act as a Disease Modifier for PRKAR1A Associated Melanotic Schwannoma?

Authors:  Erica M Roman Hernandez; Sri Laxmi Valasareddi; Jarrod Adkison; Henna Awan; Krishnamohan R Basarakodu; Arash Velayati
Journal:  Case Rep Oncol       Date:  2021-06-11
  9 in total

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