Literature DB >> 26385887

[Osteosarcoma and chondrosarcoma of the pelvis and lower extremities].

W K Guder1, J Hardes2, G Gosheger2, M Nottrott2, A Streitbürger2.   

Abstract

A wide tumor resection is essential in the therapy of primary malignant bone tumors to minimize the risk of local recurrence and ensure long-term survival. While chondrosarcoma is mainly treated surgically, osteosarcoma therapy consists of both chemotherapy and surgical resection of the tumor. While endoprosthetic replacement after hemipelvectomy tends to be associated with high infection rates and has been superseded by hip transposition and composite osteosynthetic replacements, the use of megaendoprosthetic tumor prostheses is the most common reconstruction technique when the extremities are affected. Biological reconstruction or ablative procedures are reserved for special indications. Overall, the reconstruction techniques presented in this article manage to ensure limb salvage in most patients. Functional outcome, however, greatly depends on the tumor size and site as well as postoperative residual soft tissue coverage.

Entities:  

Keywords:  Chondrosarcoma; Hemipelvectomy; Osteosarcoma; Tumor endoprosthetic reconstruction; Wide resection

Mesh:

Year:  2015        PMID: 26385887     DOI: 10.1007/s00104-015-0082-0

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  30 in total

1.  The influence of tumor- and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery. An analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols.

Authors:  D Andreou; S S Bielack; D Carrle; M Kevric; R Kotz; W Winkelmann; G Jundt; M Werner; S Fehlberg; L Kager; T Kühne; S Lang; M Dominkus; G U Exner; J Hardes; A Hillmann; V Ewerbeck; U Heise; P Reichardt; P-U Tunn
Journal:  Ann Oncol       Date:  2010-10-28       Impact factor: 32.976

Review 2.  The long-term risks of infection and amputation with limb salvage surgery using endoprostheses.

Authors:  Lee Jeys; Robert Grimer
Journal:  Recent Results Cancer Res       Date:  2009

3.  Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols.

Authors:  Stefan S Bielack; Beate Kempf-Bielack; Günter Delling; G Ulrich Exner; Silke Flege; Knut Helmke; Rainer Kotz; Mechthild Salzer-Kuntschik; Matthias Werner; Winfried Winkelmann; Andreas Zoubek; Heribert Jürgens; Kurt Winkler
Journal:  J Clin Oncol       Date:  2002-02-01       Impact factor: 44.544

4.  Pelvic reconstruction with compound osteosynthesis following hemipelvectomy: A clinical study.

Authors:  C Gebert; M Wessling; G Gosheger; M Aach; A Streitbürger; M P Henrichs; U Dirksen; J Hardes
Journal:  Bone Joint J       Date:  2013-10       Impact factor: 5.082

5.  Surgical difficulties encountered with use of modular endoprosthesis for limb preserving salvage of failed allograft reconstruction after malignant tumor resection.

Authors:  Leon S S Foo; Jendrik Hardes; Marcel Henrichs; Helmut Ahrens; Georg Gosheger; Arne Streitbürger
Journal:  J Arthroplasty       Date:  2010-08-08       Impact factor: 4.757

6.  Silver-coated megaendoprostheses in a rabbit model--an analysis of the infection rate and toxicological side effects.

Authors:  Georg Gosheger; Jendrik Hardes; Helmut Ahrens; Arne Streitburger; Horst Buerger; Michael Erren; Andreas Gunsel; Fritz H Kemper; Winfried Winkelmann; Christof Von Eiff
Journal:  Biomaterials       Date:  2004-11       Impact factor: 12.479

7.  [Bone defect reconstruction in bone sarcoma surgery: tumour endoprosthesis versus biological reconstruction].

Authors:  A Streitbürger; G Gosheger; R Dieckmann; M Nottrott; H Ahrens; J Hardes
Journal:  Unfallchirurg       Date:  2014-07       Impact factor: 1.000

8.  High complication rates with pelvic allografts. Experience of 22 sarcoma resections.

Authors:  T Ozaki; A Hillmann; D Bettin; P Wuisman; W Winkelmann
Journal:  Acta Orthop Scand       Date:  1996-08

9.  Resection and reconstruction for primary neoplasms involving the innominate bone.

Authors:  W F Enneking; W K Dunham
Journal:  J Bone Joint Surg Am       Date:  1978-09       Impact factor: 5.284

10.  Biological reconstruction following the resection of malignant bone tumors of the pelvis.

Authors:  Frank Traub; Dimosthenis Andreou; Maya Niethard; Carmen Tiedke; Mathias Werner; Per-Ulf Tunn
Journal:  Sarcoma       Date:  2013-04-03
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  4 in total

1.  The overexpression of miR-30a affects cell proliferation of chondrosarcoma via targeting Runx2.

Authors:  Dong Jiang; Xiaoming Zheng; Wei Shan; Ying Shan
Journal:  Tumour Biol       Date:  2015-11-23

2.  Reconstruction with iliac pedestal cup and proximal femur tumor prosthesis after wide resection of chondrosarcoma - 10-year follow-up results.

Authors:  Diogo Lino Moura; Rúben Fonseca; João Freitas; António Figueiredo; José Casanova
Journal:  Rev Bras Ortop       Date:  2016-12-30

3.  Classic Hodgkin lymphoma in pelvis: A case report highlights diagnosis and treatment challenges.

Authors:  Fan Tang; Li Min; Yunxia Ye; Bo Tang; Yong Zhou; Wenli Zhang; Chongqi Tu
Journal:  Medicine (Baltimore)       Date:  2017-09       Impact factor: 1.889

4.  Enneking type III resection of pubic chondrosarcoma: A case report.

Authors:  A Zaizi; R Badaoui; A Rabah; M Aboulfateh; M R Khmamouch; A S Bouabid; M Boussouga
Journal:  Ann Med Surg (Lond)       Date:  2022-01-25
  4 in total

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