Literature DB >> 26385812

Stem Cell Therapy: Current Applications and Potential for Urology.

Bridget Wiafe1, Peter D Metcalfe2, Adetola B Adesida3.   

Abstract

Stem cell therapy holds the potential to revolutionize the treatment of a number of chronic conditions. Stem cells ability to home in on injured sites of the body, stimulate angiogenesis, tissue regeneration, immunomodulation, anti-inflammatory, and anti-fibrotic factors have attracted their use in the treatment of many conditions. Urology has registered one of the highest experimental successes using stem cell therapy. However, the rate of clinical applications is comparatively lower. This review takes a look at our efforts so far and what needs to be done in order to maximize the clinical benefit we can derive from stem cells.

Keywords:  Bladder obstruction; Immunomodulation; Mesenchymal; Renal fibrosis; Stem cells; Urinary incontinence

Mesh：

Year:  2015        PMID： 26385812     DOI： 10.1007/s11934-015-0551-5

Source DB:  PubMed          Journal:  Curr Urol Rep        ISSN： 1527-2737            Impact factor:   3.092


  89 in total

1.  Autologous bone marrow mesenchymal stem cell transplantation in liver failure patients caused by hepatitis B: short-term and long-term outcomes.

Authors:  Liang Peng; Dong-ying Xie; Bing-Liang Lin; Jing Liu; Hai-peng Zhu; Chan Xie; Yu-bao Zheng; Zhi-liang Gao
Journal:  Hepatology       Date:  2011-07-14       Impact factor: 17.425

2.  Arterially delivered mesenchymal stem cells prevent obstruction-induced renal fibrosis.

Authors:  Hiroshi Asanuma; Brian A Vanderbrink; Matthew T Campbell; Karen L Hile; Hongji Zhang; Daniel R Meldrum; Kirstan K Meldrum
Journal:  J Surg Res       Date:  2010-07-08       Impact factor: 2.192

3.  Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients.

Authors:  Zheng Zhang; Hu Lin; Ming Shi; Ruonan Xu; Junliang Fu; Jiyun Lv; Liming Chen; Sa Lv; Yuanyuan Li; Shuangjie Yu; Hua Geng; Lei Jin; George K K Lau; Fu-Sheng Wang
Journal:  J Gastroenterol Hepatol       Date:  2012-03       Impact factor: 4.029

4.  Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study.

Authors:  Marlies E J Reinders; Johan W de Fijter; Helene Roelofs; Ingeborg M Bajema; Dorottya K de Vries; Alexander F Schaapherder; Frans H J Claas; Paula P M C van Miert; Dave L Roelen; Cees van Kooten; Willem E Fibbe; Ton J Rabelink
Journal:  Stem Cells Transl Med       Date:  2013-01-24       Impact factor: 6.940

5.  The long-term results of skin inlay urethroplasty.

Authors:  A R Mundy
Journal:  Br J Urol       Date:  1995-01

6.  IFN-gamma and TNF-alpha differentially regulate immunomodulation by murine mesenchymal stem cells.

Authors:  Karen English; Frank P Barry; Ciara P Field-Corbett; Bernard P Mahon
Journal:  Immunol Lett       Date:  2007-04-26       Impact factor: 3.685

7.  Multipotential differentiation of human urine-derived stem cells: potential for therapeutic applications in urology.

Authors:  Shantaram Bharadwaj; Guihua Liu; Yingai Shi; Rongpei Wu; Bin Yang; Tongchuan He; Yuxin Fan; Xinyan Lu; Xiaobo Zhou; Hong Liu; Anthony Atala; Jan Rohozinski; Yuanyuan Zhang
Journal:  Stem Cells       Date:  2013-09       Impact factor: 5.845

8.  Effect of αlipoic acid and silymarin on bladder outlet obstruction.

Authors:  Abidin Yildirim; Barbaros Başeskioğlu; Halide E Temel; Nilüfer Erkasap; Aydin Yenilmez; Sema Uslu; Caner Ozer; Mete Ozkurt; Turgut Dönmez
Journal:  Exp Ther Med       Date:  2012-11-23       Impact factor: 2.447

9.  Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice.

Authors:  Ghazanfar Ali Nasir; Sadia Mohsin; Mohsin Khan; Sulaiman Shams; Gibran Ali; Shaheen N Khan; Sheikh Riazuddin
Journal:  J Transl Med       Date:  2013-03-26       Impact factor: 5.531

10.  Mesenchymal stem cells (MSC) prevented the progression of renovascular hypertension, improved renal function and architecture.

Authors:  Elizabeth B Oliveira-Sales; Edgar Maquigussa; Patricia Semedo; Luciana G Pereira; Vanessa M Ferreira; Niels O Câmara; Cassia T Bergamaschi; Ruy R Campos; Mirian A Boim
Journal:  PLoS One       Date:  2013-11-04       Impact factor: 3.240
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  2 in total

1.  Autophagy Improves the Immunosuppression of CD4+ T Cells by Mesenchymal Stem Cells Through Transforming Growth Factor-β1.

Authors:  Liangbin Gao; Shuizhong Cen; Peng Wang; Zhongyu Xie; Zhenhua Liu; Wen Deng; Hongjun Su; Xiaohua Wu; Shan Wang; Jinteng Li; Yi Ouyang; Yanfeng Wu; Huiyong Shen
Journal:  Stem Cells Transl Med       Date:  2016-07-11       Impact factor: 6.940

2.  Mesenchymal stem cells inhibit hypoxia-induced inflammatory and fibrotic pathways in bladder smooth muscle cells.

Authors:  Bridget Wiafe; Adetola Adesida; Thomas Churchill; Peter Metcalfe
Journal:  World J Urol       Date:  2018-03-02       Impact factor: 4.226
  2 in total

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