Literature DB >> 26383829

Ovarian cancer in France: trends in incidence, mortality and survival, 1980-2012.

Brigitte Trétarre1, Florence Molinié2, Anne-Sophie Woronoff3, Nadine Bossard4, Faiza Bessaoud5, Emilie Marrer6, Pascale Grosclaude7, Anne-Valérie Guizard8, Patricia Delafosse9, Simona Bara10, Michel Velten11, Bénédicte Lapôtre-Ledoux12, Karine Ligier13, Nathalie Léone14, Patrick Arveux15, Zoé Uhry16.   

Abstract

OBJECTIVE: The aim of this epidemiological study was to describe the incidence, mortality and survival of ovarian cancer (OC) in France, according to age, period of diagnosis, and histological type.
METHODS: Incidence and mortality were estimated from 1980 to 2012 based on data in French cancer registries and from the Centre for Epidemiology of Causes of Death (CépiDc-Inserm) up to 2009. Net survival was estimated from registry data using the Pohar-Perme method, on cases diagnosed between 1989 and 2010, with date of last follow-up set at 30 June 2013.
RESULTS: In 2012, 4615 cases of OC were diagnosed in France, and 3140 women died from OC. World population age-standardized incidence and mortality rates declined by respectively 0.6% and 1.2% per year between 1980 and 2012. Net survival at 5years increased slightly, from 40% for the period 1989-1993 to 45% for the period 2005-2010. Net survival varied considerably according to histological type. Germ cell tumors had better net survival at 10years (81%) compared to epithelial tumors (32%), sex cord-stromal tumors (40%) and tumors without biopsy (8%).
CONCLUSIONS: Our study shows a decline in incidence and mortality rates from ovarian cancer in France between 1980 and 2012, but net survival remains poor overall, and improved only slightly over the whole study period.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Histological type; Incidence; Mortality; Ovarian cancer; Survival

Mesh:

Year:  2015        PMID: 26383829     DOI: 10.1016/j.ygyno.2015.09.013

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  11 in total

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