Hwon-Ham Park1, Hyun-Young Kim2, Sung-Eun Jung1, Seong-Cheol Lee1, Kwi-Won Park1. 1. Department of Pediatric Surgery, Seoul National University Children's Hospital, Seoul, Korea. 2. Department of Pediatric Surgery, Seoul National University Children's Hospital, Seoul, Korea. Electronic address: spkhy02@snu.ac.kr.
Abstract
PURPOSE: The purpose of this study was to analyze the long-term outcomes, such as nutritional status, pancreatic function, gastrointestinal (GI) function, and quality of life (QOL), in children who underwent pylorus-preserving pancreaticoduodenectomy (PPPD). METHODS: Between 1992 and 2013, there were 15 children who underwent PPPD at Seoul National University Children's Hospital, and 10 of them participated in this study. A retrospective review of the patients' medical records and follow-up was done. Their nutritional statuses were estimated by height, body weight, weight for age Z-score, body mass index (BMI), and serum protein, albumin levels. The endocrine and exocrine functions of the pancreas were estimated by diabetes mellitus (DM), steatorrhea, and Bristol stool chart. The GI function and QOL were evaluated via questionnaires. The follow-up period ranged from 3 to 18years. RESULTS: There were no severe growth disturbances, 6 patients experienced mild steatorrhea and 3 showed above the category 6 in Bristol stool chart. All the patients experienced mild GI symptoms. As for the QOL, there were no significant negative answers, except for one patient with DM. CONCLUSIONS: Almost all the study subjects, who underwent PPPD in their childhood, did not present significant problems except for one patient with DM.
PURPOSE: The purpose of this study was to analyze the long-term outcomes, such as nutritional status, pancreatic function, gastrointestinal (GI) function, and quality of life (QOL), in children who underwent pylorus-preserving pancreaticoduodenectomy (PPPD). METHODS: Between 1992 and 2013, there were 15 children who underwent PPPD at Seoul National University Children's Hospital, and 10 of them participated in this study. A retrospective review of the patients' medical records and follow-up was done. Their nutritional statuses were estimated by height, body weight, weight for age Z-score, body mass index (BMI), and serum protein, albumin levels. The endocrine and exocrine functions of the pancreas were estimated by diabetes mellitus (DM), steatorrhea, and Bristol stool chart. The GI function and QOL were evaluated via questionnaires. The follow-up period ranged from 3 to 18years. RESULTS: There were no severe growth disturbances, 6 patients experienced mild steatorrhea and 3 showed above the category 6 in Bristol stool chart. All the patients experienced mild GI symptoms. As for the QOL, there were no significant negative answers, except for one patient with DM. CONCLUSIONS: Almost all the study subjects, who underwent PPPD in their childhood, did not present significant problems except for one patient with DM.
Authors: Seung-Min Park; Daeyoun D Won; Brian J Lee; Diego Escobedo; Andre Esteva; Amin Aalipour; T Jessie Ge; Jung Ha Kim; Susie Suh; Elliot H Choi; Alexander X Lozano; Chengyang Yao; Sunil Bodapati; Friso B Achterberg; Jeesu Kim; Hwan Park; Youngjae Choi; Woo Jin Kim; Jung Ho Yu; Alexander M Bhatt; Jong Kyun Lee; Ryan Spitler; Shan X Wang; Sanjiv S Gambhir Journal: Nat Biomed Eng Date: 2020-04-06 Impact factor: 25.671