Literature DB >> 26379965

Associations of immunity-related single nucleotide polymorphisms with overall survival among prostate cancer patients.

Fayth L Miles1, Jian-Yu Rao2, Curtis Eckhert3, Shen-Chih Chang1, Allan Pantuck4, Zuo-Feng Zhang5.   

Abstract

The progression of prostate cancer is influenced by systemic inflammation, and may be attributed, in part, to genetic predisposition. Single nucleotide polymorphisms associated with the immune response may help mediate prostate cancer progression. We analyzed data from a hospital-based case-control study of 164 prostate cancer patients and 157 healthy male controls from the Memorial Sloan Kettering Cancer Center. We evaluated associations between six immunity-related polymorphisms (CRP rs1205 and rs1800947, FGFR2 rs1219648 and rs2981582, IFNGR1 rs11914, and IL10 rs1800871) and overall survival among prostate cancer patients, calculating adjusted hazard ratios (HR) and 95% confidence intervals (CI) using Cox proportional hazards regression. FGFR2 rs1219648 (GG vs. AA) and rs2981582 (TT vs. CC) polymorphisms were associated with more favorable overall survival (HR: 0.13, 95% CI: 0.03-0.62 and HR: 0.13, 95% CI: 0.03-0.53, respectively) in patients with primary prostate cancer. These observations highlight the need to validate and identify these and other immunity-related polymorphisms in larger studies examining survival of prostate cancer patients.

Entities:  

Keywords:  Genetic predisposition; case-control; immune response; polymorphisms; proportional hazards model; prostate cancer

Year:  2015        PMID： 26379965      PMCID： PMC4565348     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN： 1940-5901


  17 in total

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Journal:  Nat Genet       Date:  2007-05-27       Impact factor: 38.330

2.  Tobacco smoking, GSTP1 polymorphism, and bladder carcinoma.

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Journal:  Cancer       Date:  2005-12-01       Impact factor: 6.860

3.  Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.

Authors:  Antonis C Antoniou; Jonathan Beesley; Lesley McGuffog; Olga M Sinilnikova; Sue Healey; Susan L Neuhausen; Yuan Chun Ding; Timothy R Rebbeck; Jeffrey N Weitzel; Henry T Lynch; Claudine Isaacs; Patricia A Ganz; Gail Tomlinson; Olufunmilayo I Olopade; Fergus J Couch; Xianshu Wang; Noralane M Lindor; Vernon S Pankratz; Paolo Radice; Siranoush Manoukian; Bernard Peissel; Daniela Zaffaroni; Monica Barile; Alessandra Viel; Anna Allavena; Valentina Dall'Olio; Paolo Peterlongo; Csilla I Szabo; Michal Zikan; Kathleen Claes; Bruce Poppe; Lenka Foretova; Phuong L Mai; Mark H Greene; Gad Rennert; Flavio Lejbkowicz; Gord Glendon; Hilmi Ozcelik; Irene L Andrulis; Mads Thomassen; Anne-Marie Gerdes; Lone Sunde; Dorthe Cruger; Uffe Birk Jensen; Maria Caligo; Eitan Friedman; Bella Kaufman; Yael Laitman; Roni Milgrom; Maya Dubrovsky; Shimrit Cohen; Ake Borg; Helena Jernström; Annika Lindblom; Johanna Rantala; Marie Stenmark-Askmalm; Beatrice Melin; Kate Nathanson; Susan Domchek; Ania Jakubowska; Jan Lubinski; Tomasz Huzarski; Ana Osorio; Adriana Lasa; Mercedes Durán; Maria-Isabel Tejada; Javier Godino; Javier Benitez; Ute Hamann; Mieke Kriege; Nicoline Hoogerbrugge; Rob B van der Luijt; Christi J van Asperen; Peter Devilee; E J Meijers-Heijboer; Marinus J Blok; Cora M Aalfs; Frans Hogervorst; Matti Rookus; Margaret Cook; Clare Oliver; Debra Frost; Don Conroy; D Gareth Evans; Fiona Lalloo; Gabriella Pichert; Rosemarie Davidson; Trevor Cole; Jackie Cook; Joan Paterson; Shirley Hodgson; Patrick J Morrison; Mary E Porteous; Lisa Walker; M John Kennedy; Huw Dorkins; Susan Peock; Andrew K Godwin; Dominique Stoppa-Lyonnet; Antoine de Pauw; Sylvie Mazoyer; Valérie Bonadona; Christine Lasset; Hélène Dreyfus; Dominique Leroux; Agnès Hardouin; Pascaline Berthet; Laurence Faivre; Catherine Loustalot; Tetsuro Noguchi; Hagay Sobol; Etienne Rouleau; Catherine Nogues; Marc Frénay; Laurence Vénat-Bouvet; John L Hopper; Mary B Daly; Mary B Terry; Esther M John; Saundra S Buys; Yosuf Yassin; Alexander Miron; David Goldgar; Christian F Singer; Anne Catharina Dressler; Daphne Gschwantler-Kaulich; Georg Pfeiler; Thomas V O Hansen; Lars Jønson; Bjarni A Agnarsson; Tomas Kirchhoff; Kenneth Offit; Vincent Devlin; Ana Dutra-Clarke; Marion Piedmonte; Gustavo C Rodriguez; Katie Wakeley; John F Boggess; Jack Basil; Peter E Schwartz; Stephanie V Blank; Amanda Ewart Toland; Marco Montagna; Cinzia Casella; Evgeny Imyanitov; Laima Tihomirova; Ignacio Blanco; Conxi Lazaro; Susan J Ramus; Lara Sucheston; Beth Y Karlan; Jenny Gross; Rita Schmutzler; Barbara Wappenschmidt; Christoph Engel; Alfons Meindl; Magdalena Lochmann; Norbert Arnold; Simone Heidemann; Raymonda Varon-Mateeva; Dieter Niederacher; Christian Sutter; Helmut Deissler; Dorothea Gadzicki; Sabine Preisler-Adams; Karin Kast; Ines Schönbuchner; Trinidad Caldes; Miguel de la Hoya; Kristiina Aittomäki; Heli Nevanlinna; Jacques Simard; Amanda B Spurdle; Helene Holland; Xiaoqing Chen; Radka Platte; Georgia Chenevix-Trench; Douglas F Easton
Journal:  Cancer Res       Date:  2010-11-30       Impact factor: 12.701

4.  Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk.

Authors:  E A Tindall; G Severi; H N Hoang; C S Ma; P Fernandez; M C Southey; D R English; J L Hopper; C F Heyns; S G Tangye; G G Giles; V M Hayes
Journal:  Carcinogenesis       Date:  2010-04-19       Impact factor: 4.944

5.  Interleukin-6 promoter variants, prostate cancer risk, and survival.

Authors:  Elizabeth A Tindall; Gianluca Severi; Hoa N Hoang; Melissa C Southey; Dallas R English; John L Hopper; Graham G Giles; Vanessa M Hayes
Journal:  Prostate       Date:  2012-07-10       Impact factor: 4.104

6.  Cytokine genetic polymorphisms and prostate cancer aggressiveness.

Authors:  Jovanny Zabaleta; L Joseph Su; Hui-Yi Lin; Rosa A Sierra; M Craig Hall; A Oliver Sartor; Peter E Clark; Jennifer J Hu; Augusto C Ochoa
Journal:  Carcinogenesis       Date:  2009-05-27       Impact factor: 4.944

7.  Down-regulation of (IIIb) and (IIIc) isoforms of fibroblast growth factor receptor 2 (FGFR2) is associated with malignant progression in human prostate.

Authors:  Benyoussef Naimi; Alain Latil; Georges Fournier; Philippe Mangin; Olivier Cussenot; Philippe Berthon
Journal:  Prostate       Date:  2002-08-01       Impact factor: 4.104

8.  Common low-penetrance risk variants associated with breast cancer in Polish women.

Authors:  Joanna K Ledwoń; Ewa E Hennig; Natalia Maryan; Krzysztof Goryca; Dorota Nowakowska; Anna Niwińska; Jerzy Ostrowski
Journal:  BMC Cancer       Date:  2013-10-30       Impact factor: 4.430

9.  Genome-wide association study identifies novel breast cancer susceptibility loci.

Authors:  Douglas F Easton; Karen A Pooley; Alison M Dunning; Paul D P Pharoah; Deborah Thompson; Dennis G Ballinger; Jeffery P Struewing; Jonathan Morrison; Helen Field; Robert Luben; Nicholas Wareham; Shahana Ahmed; Catherine S Healey; Richard Bowman; Kerstin B Meyer; Christopher A Haiman; Laurence K Kolonel; Brian E Henderson; Loic Le Marchand; Paul Brennan; Suleeporn Sangrajrang; Valerie Gaborieau; Fabrice Odefrey; Chen-Yang Shen; Pei-Ei Wu; Hui-Chun Wang; Diana Eccles; D Gareth Evans; Julian Peto; Olivia Fletcher; Nichola Johnson; Sheila Seal; Michael R Stratton; Nazneen Rahman; Georgia Chenevix-Trench; Stig E Bojesen; Børge G Nordestgaard; Christen K Axelsson; Montserrat Garcia-Closas; Louise Brinton; Stephen Chanock; Jolanta Lissowska; Beata Peplonska; Heli Nevanlinna; Rainer Fagerholm; Hannaleena Eerola; Daehee Kang; Keun-Young Yoo; Dong-Young Noh; Sei-Hyun Ahn; David J Hunter; Susan E Hankinson; David G Cox; Per Hall; Sara Wedren; Jianjun Liu; Yen-Ling Low; Natalia Bogdanova; Peter Schürmann; Thilo Dörk; Rob A E M Tollenaar; Catharina E Jacobi; Peter Devilee; Jan G M Klijn; Alice J Sigurdson; Michele M Doody; Bruce H Alexander; Jinghui Zhang; Angela Cox; Ian W Brock; Gordon MacPherson; Malcolm W R Reed; Fergus J Couch; Ellen L Goode; Janet E Olson; Hanne Meijers-Heijboer; Ans van den Ouweland; André Uitterlinden; Fernando Rivadeneira; Roger L Milne; Gloria Ribas; Anna Gonzalez-Neira; Javier Benitez; John L Hopper; Margaret McCredie; Melissa Southey; Graham G Giles; Chris Schroen; Christina Justenhoven; Hiltrud Brauch; Ute Hamann; Yon-Dschun Ko; Amanda B Spurdle; Jonathan Beesley; Xiaoqing Chen; Arto Mannermaa; Veli-Matti Kosma; Vesa Kataja; Jaana Hartikainen; Nicholas E Day; David R Cox; Bruce A J Ponder
Journal:  Nature       Date:  2007-06-28       Impact factor: 49.962

10.  Genetic polymorphisms of RANTES, IL1-A, MCP-1 and TNF-A genes in patients with prostate cancer.

Authors:  Pablo Sáenz-López; Rafael Carretero; José Manuel Cózar; José Maria Romero; Julia Canton; José Ramón Vilchez; Miguel Tallada; Federico Garrido; Francisco Ruiz-Cabello
Journal:  BMC Cancer       Date:  2008-12-19       Impact factor: 4.430
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Journal:  Oncol Lett       Date:  2017-03-10       Impact factor: 2.967

2.  Determination of SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, and RAGE rs1800625 Single Gene Polymorphisms in Patients with Laryngeal Squamous Cell Carcinoma.

Authors:  Virgilijus Uloza; Toma Tamauskaite; Alvita Vilkeviciute; Agne Pasvenskaite; Vykintas Liutkevicius; Rasa Liutkeviciene
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