| Literature DB >> 26358418 |
Ari Feder1, Joseph Burger1, Shan Gao1, Efraim Lewinsohn1, Nurit Katzir1, Arthur A Schaffer1, Ayala Meir1, Rachel Davidovich-Rikanati1, Vitaly Portnoy1, Amit Gal-On1, Zhangjun Fei1, Yechezkel Kashi1, Yaakov Tadmor2.
Abstract
The flavonoids are phenylpropanoid-derived metabolites that are ubiquitous in plants, playing many roles in growth and development. Recently, we observed that fruit rinds of yellow casaba muskmelons (Cucumis melo 'Inodorous Group') accumulate naringenin chalcone, a yellow flavonoid pigment. With RNA-sequencing analysis of bulked segregants representing the tails of a population segregating for naringenin chalcone accumulation followed by fine mapping and genetic transformation, we identified a Kelch domain-containing F-box protein coding (CmKFB) gene that, when expressed, negatively regulates naringenin chalcone accumulation. Additional metabolite analysis indicated that downstream flavonoids are accumulated together with naringenin chalcone, whereas CmKFB expression diverts the biochemical flux toward coumarins and general phenylpropanoids. These results show that CmKFB functions as a posttranscriptional regulator that diverts flavonoid metabolic flux.Entities:
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Year: 2015 PMID： 26358418 PMCID： PMC4634078 DOI： 10.1104/pp.15.01008
Source DB: PubMed Journal: Plant Physiol ISSN： 0032-0889 Impact factor: 8.340