Tarja H Välimäki1,2, Janne A Martikainen3, Kristiina Hongisto4, Saku Väätäinen5, Harri Sintonen6, Anne M Koivisto7,8. 1. Department of Nursing Science, University of Eastern Finland, P.O.Box 1627, 70211, Kuopio, Finland. tarja.valimaki@uef.fi. 2. Unit of Nursing Development, Clinical Education and Research, Kuopio University Hospital (KYS), P.O.Box 100, 70029, Kuopio, Finland. tarja.valimaki@uef.fi. 3. Pharmacoeconomics and Outcomes Research Unit, School of Pharmacy, University of Eastern Finland, P.O.Box 1627, 70211, Kuopio, Finland. janne.martikainen@uef.fi. 4. Department of Geriatrics, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O.Box 1627, 70211, Kuopio, Finland. kristiina.hongisto@kuh.fi. 5. Pharmacoeconomics and Outcomes Research Unit, School of Pharmacy, University of Eastern Finland, P.O.Box 1627, 70211, Kuopio, Finland. 6. Department of Public Health, University of Helsinki, PL 41, 00014, Helsinki, Finland. harri.sintonen@helsinki.fi. 7. Institute of Clinical Medicine, Neurology, University of Eastern Finland, P.O.Box 1627, 70211, Kuopio, Finland. anne.koivisto@kuh.fi. 8. Neurology of Neuro Center, Kuopio University Hospital (KYS), P.O.Box 100, 70029, Kuopio, Finland. anne.koivisto@kuh.fi.
Abstract
PURPOSE: To examine caregivers' health-related quality of life (HRQoL) and well-being during the first 3 years after their family member's Alzheimer's disease (AD) diagnosis and assessed the relationship between caregivers' HRQoL, well-being, and the severity of AD. Further, to compare of caregivers' HRQoL to general population. METHODS: Longitudinal design (36 months) after AD diagnosis of 236 caregiver-patient dyads. Linear regression was used to assess age- and gender-adjusted association between repeated measurements of caregivers' HRQoL and the severity of AD. For comparison with general population, the National Health 2011 Health Examination Survey data was utilized. RESULTS: Caregivers had significantly lower HRQoL than age- and gender-standardized counterparts. Severity of AD was significantly (p < 0.05) associated with the mobility and depression dimensions of caregiver's HRQoL but not with the total HRQoL index score. CONCLUSIONS: Caregivers' HRQoL seems to deteriorate earlier than previously noted. The severity of AD has not that great impact on caregiver's HRQoL as assumed.
PURPOSE: To examine caregivers' health-related quality of life (HRQoL) and well-being during the first 3 years after their family member's Alzheimer's disease (AD) diagnosis and assessed the relationship between caregivers' HRQoL, well-being, and the severity of AD. Further, to compare of caregivers' HRQoL to general population. METHODS: Longitudinal design (36 months) after AD diagnosis of 236 caregiver-patient dyads. Linear regression was used to assess age- and gender-adjusted association between repeated measurements of caregivers' HRQoL and the severity of AD. For comparison with general population, the National Health 2011 Health Examination Survey data was utilized. RESULTS: Caregivers had significantly lower HRQoL than age- and gender-standardized counterparts. Severity of AD was significantly (p < 0.05) associated with the mobility and depression dimensions of caregiver's HRQoL but not with the total HRQoL index score. CONCLUSIONS: Caregivers' HRQoL seems to deteriorate earlier than previously noted. The severity of AD has not that great impact on caregiver's HRQoL as assumed.
Entities:
Keywords:
15D; Alzheimer’s disease; Family caregivers; Health-related quality of life; Psychological distress
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