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Literature DB >> 26341526

PACE4 (PCSK6): another proprotein convertase link to iron homeostasis?

Johann Guillemot¹, Nabil G Seidah².

Abstract

Entities: Chemical Gene

Keywords: PACEA; iron homeostasis; proproteinconvertase; transferrin receptor-2

Mesh：

Substances：

Year: 2015 PMID： 26341526 PMCID： PMC4800706 DOI： 10.3324/haematol.2015.127175

Source DB: PubMed Journal: Haematologica ISSN： 0390-6078 Impact factor: 9.941

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10 in total

1. The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.

Authors: Nadia Nour; Gaétan Mayer; John S Mort; Alexandre Salvas; Majambu Mbikay; Charlotte J Morrison; Christopher M Overall; Nabil G Seidah
Journal: Mol Biol Cell Date: 2005-08-31 Impact factor: 4.138

2. BMP6 orchestrates iron metabolism.

Authors: Clara Camaschella
Journal: Nat Genet Date: 2009-04 Impact factor: 38.330

3. Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis.

Authors: R E Fleming; M C Migas; C C Holden; A Waheed; R S Britton; S Tomatsu; B R Bacon; W S Sly
Journal: Proc Natl Acad Sci U S A Date: 2000-02-29 Impact factor: 11.205

4. Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse.

Authors: Rachid Essalmani; Josée Hamelin; Jadwiga Marcinkiewicz; Ann Chamberland; Majambu Mbikay; Michel Chrétien; Nabil G Seidah; Annik Prat
Journal: Mol Cell Biol Date: 2006-01 Impact factor: 4.272

Review 5. The biology and therapeutic targeting of the proprotein convertases.

Authors: Nabil G Seidah; Annik Prat
Journal: Nat Rev Drug Discov Date: 2012-05 Impact factor: 84.694

6. Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme 4 is required for chondrogenic differentiation in ATDC5 cells.

Authors: Keizo Yuasa; Go Futamatsu; Tsuyoshi Kawano; Masaki Muroshita; Yoko Kageyama; Hiromi Taichi; Hiroshi Ishikawa; Masami Nagahama; Yoshiko Matsuda; Akihiko Tsuji
Journal: FEBS J Date: 2012-09-17 Impact factor: 5.542

7. Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.

Authors: Johann Guillemot; Maryssa Canuel; Rachid Essalmani; Annik Prat; Nabil G Seidah
Journal: Hepatology Date: 2013-05-15 Impact factor: 17.425

8. Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.

Authors: Rachid Essalmani; Delia Susan-Resiga; Ann Chamberland; Marie-Claude Asselin; Maryssa Canuel; Daniel Constam; John W Creemers; Robert Day; Dany Gauthier; Annik Prat; Nabil G Seidah
Journal: J Biol Chem Date: 2013-08-05 Impact factor: 5.157

9. Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis.

Authors: Laura Silvestri; Alessia Pagani; Clara Camaschella
Journal: Blood Date: 2007-10-15 Impact factor: 22.113

10. Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form.

Authors: Alessia Pagani; Maud Vieillevoye; Antonella Nai; Marco Rausa; Meriem Ladli; Catherine Lacombe; Patrick Mayeux; Frédérique Verdier; Clara Camaschella; Laura Silvestri
Journal: Haematologica Date: 2015-01-30 Impact factor: 9.941