Literature DB >> 19338078

BMP6 orchestrates iron metabolism.

Clara Camaschella1.   

Abstract

The small liver peptide hepcidin is a major regulator of systemic iron homeostasis in mammals, adapting iron absorption to the body's demands. Two new studies now identify BMP6 as the key endogenous regulator of hepcidin.

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Year:  2009        PMID： 19338078     DOI： 10.1038/ng0409-386

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  15 in total

Review 1.  Regulation of iron acquisition and iron distribution in mammals.

Authors:  Tomas Ganz; Elizabeta Nemeth
Journal:  Biochim Biophys Acta       Date:  2006-05-12

Review 2.  Forging a field: the golden age of iron biology.

Authors:  Nancy C Andrews
Journal:  Blood       Date:  2008-07-15       Impact factor: 22.113

3.  A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression.

Authors:  Rui-Hong Wang; Cuiling Li; Xiaoling Xu; Yin Zheng; Cuiying Xiao; Patricia Zerfas; Sharon Cooperman; Michael Eckhaus; Tracey Rouault; Lopa Mishra; Chu-Xia Deng
Journal:  Cell Metab       Date:  2005-12       Impact factor: 27.287

4.  Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.

Authors:  Jodie L Babitt; Franklin W Huang; Diedra M Wrighting; Yin Xia; Yisrael Sidis; Tarek A Samad; Jason A Campagna; Raymond T Chung; Alan L Schneyer; Clifford J Woolf; Nancy C Andrews; Herbert Y Lin
Journal:  Nat Genet       Date:  2006-04-09       Impact factor: 38.330

5.  Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

Authors:  G Winnier; M Blessing; P A Labosky; B L Hogan
Journal:  Genes Dev       Date:  1995-09-01       Impact factor: 11.361

6.  Mice lacking Bmp6 function.

Authors:  M J Solloway; A T Dudley; E K Bikoff; K M Lyons; B L Hogan; E J Robertson
Journal:  Dev Genet       Date:  1998

7.  Lack of the bone morphogenetic protein BMP6 induces massive iron overload.

Authors:  Delphine Meynard; Léon Kautz; Valérie Darnaud; François Canonne-Hergaux; Hélène Coppin; Marie-Paule Roth
Journal:  Nat Genet       Date:  2009-03-01       Impact factor: 38.330

8.  Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance.

Authors:  Jodie L Babitt; Franklin W Huang; Yin Xia; Yisrael Sidis; Nancy C Andrews; Herbert Y Lin
Journal:  J Clin Invest       Date:  2007-07       Impact factor: 14.808

9.  Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis.

Authors:  Antonella Roetto; George Papanikolaou; Marianna Politou; Federica Alberti; Domenico Girelli; John Christakis; Dimitris Loukopoulos; Clara Camaschella
Journal:  Nat Genet       Date:  2002-12-09       Impact factor: 38.330

Review 10.  Understanding iron homeostasis through genetic analysis of hemochromatosis and related disorders.

Authors:  Clara Camaschella
Journal:  Blood       Date:  2005-07-19       Impact factor: 22.113
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  20 in total

Review 1.  Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation.

Authors:  Chia Chi Sun; Valentina Vaja; Jodie L Babitt; Herbert Y Lin
Journal:  Am J Hematol       Date:  2012-01-31       Impact factor: 10.047

2.  Interrelationships between tissue iron status and erythropoiesis during postweaning development following neonatal iron deficiency in rats.

Authors:  Narasimha V Hegde; Erica L Unger; Gordon L Jensen; Pamela A Hankey; Robert F Paulson
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-12-30       Impact factor: 4.052

3.  Bone morphogenetic proteins.

Authors:  Dwight A Towler
Journal:  Blood       Date:  2009-09-03       Impact factor: 22.113

4.  Iron metabolic disorder in chronic hepatitis C: insights from recent evidence.

Authors:  Keisuke Hino; Sohji Nishina; Yuichi Hara
Journal:  Clin J Gastroenterol       Date:  2012-07-31

5.  Galvanic microparticles increase migration of human dermal fibroblasts in a wound-healing model via reactive oxygen species pathway.

Authors:  Nina Tandon; Elisa Cimetta; Aranzazu Villasante; Nicolette Kupferstein; Michael D Southall; Ali Fassih; Junxia Xie; Ying Sun; Gordana Vunjak-Novakovic
Journal:  Exp Cell Res       Date:  2013-10-07       Impact factor: 3.905

6.  Identification of satellite cells from anole lizard skeletal muscle and demonstration of expanded musculoskeletal potential.

Authors:  Joanna Palade; Djordje Djordjevic; Elizabeth D Hutchins; Rajani M George; John A Cornelius; Alan Rawls; Joshua W K Ho; Kenro Kusumi; Jeanne Wilson-Rawls
Journal:  Dev Biol       Date:  2017-12-25       Impact factor: 3.582

7.  Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.

Authors:  Elena Corradini; Molly Rozier; Delphine Meynard; Adam Odhiambo; Herbert Y Lin; Qi Feng; Mary C Migas; Robert S Britton; Jodie L Babitt; Robert E Fleming
Journal:  Gastroenterology       Date:  2011-07-13       Impact factor: 22.682

Review 8.  Recent advances in iron metabolism and related disorders.

Authors:  Clara Camaschella; Paolo Strati
Journal:  Intern Emerg Med       Date:  2010-04-28       Impact factor: 3.397

Review 9.  The role of hepcidin in iron metabolism.

Authors:  Elizabeta Nemeth; Tomas Ganz
Journal:  Acta Haematol       Date:  2009-11-10       Impact factor: 2.195

10.  Heritability of serum iron measures in the hemochromatosis and iron overload screening (HEIRS) family study.

Authors:  Christine E McLaren; James C Barton; John H Eckfeldt; Gordon D McLaren; Ronald T Acton; Paul C Adams; Leora F Henkin; Victor R Gordeuk; Chris D Vulpe; Emily L Harris; Barbara W Harrison; Jacob A Reiss; Beverly M Snively
Journal:  Am J Hematol       Date:  2010-02       Impact factor: 10.047
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