Literature DB >> 26339362

Intraoperative pathology consultation for pulmonary lesions: errors and deferrals.

Elif Ulker Akyildiz1.   

Abstract

The accuracy rate of frozen section constitutes an important step of quality assessment step in pathology practice. This study aimed to investigate pulmonary lesions that were incorrectly diagnosed or postponed for routine examination by pathologists at frozen section examination; it also aimed to discuss the reasons for difficult diagnoses and the various clues enabling the correct diagnosis to be made when such lesions are encountered. This study retrospectively reviewed the medical data of the thoracic surgery cases that underwent frozen section examination between 2009 and 2014. Frozen section errors and deferrals were identified in 25 cases. Fourteen (56%) lesions were of pulmonary parenchymal origin and 11 (44%) were of pleural origin. The number of cases in which the pathologists postponed the diagnosis without making any approach was 14. Of these, 9 (64%) were benign lesions such as bronchiectasis, fibrosis anthracosis, chronic inflammatory cell infiltration, chronic pleuritis, and mesothelial proliferation. The number of misdiagnosed cases was 11. Of these, 7 (64%) were of pulmonary and 4 (36%) were of pleural origin. Because the examination techniques of each pathology department may differ from one another, the comparative examination of frozen sections and routine sections would aid in becoming familiar with various pathologies and would be beneficial for pathologists in minimizing their diagnostic errors.

Entities:  

Keywords:  Frozen section; intraoperative pathology consultation; pulmonary lesion

Mesh:

Year:  2015        PMID: 26339362      PMCID: PMC4555690     

Source DB:  PubMed          Journal:  Int J Clin Exp Pathol        ISSN: 1936-2625


  4 in total

Review 1.  Frozen section of lung specimens.

Authors:  Anna Sienko; Timothy Craig Allen; Dani S Zander; Philip T Cagle
Journal:  Arch Pathol Lab Med       Date:  2005-12       Impact factor: 5.534

Review 2.  Frozen section diagnoses of small pulmonary nodules: accuracy and clinical implications.

Authors:  Alberto M Marchevsky; Chanikarn Changsri; Indu Gupta; Clark Fuller; Ward Houck; Robert J McKenna
Journal:  Ann Thorac Surg       Date:  2004-11       Impact factor: 4.330

Review 3.  Diffuse malignant mesothelioma.

Authors:  Sergio Pina Oviedo; Philip T Cagle
Journal:  Arch Pathol Lab Med       Date:  2012-08       Impact factor: 5.534

4.  Lessons learned from mistakes and deferrals in the frozen section diagnosis of bronchioloalveolar carcinoma and well-differentiated pulmonary adenocarcinoma: an evidence-based pathology approach.

Authors:  Ruta Gupta; Robert McKenna; Alberto M Marchevsky
Journal:  Am J Clin Pathol       Date:  2008-07       Impact factor: 2.493

  4 in total
  2 in total

1.  Definitive lobectomy without frozen section analysis is a treatment option for large or deep nodules selected carefully with clinical diagnosis of malignancy.

Authors:  Shohei Mori; Yuki Noda; Takamasa Shibazaki; Daiki Kato; Hideki Matsudaira; Jun Hirano; Takashi Ohtsuka
Journal:  Thorac Cancer       Date:  2020-05-22       Impact factor: 3.500

2.  Factors associated with discrepancy between fresh frozen and permanent biopsy from medical thoracoscopy: single center analysis of 172 medical flexible thoracoscopy cases.

Authors:  Jeong Uk Lim; Jongyeol Oh; Hyung Woo Kim; Woo Ho Ban; Eun Su Park; Jick Hwan Ha; Ju Sang Kim; Sang Haak Lee
Journal:  J Thorac Dis       Date:  2020-12       Impact factor: 2.895

  2 in total

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