CONTEXT: Frozen section of lung tissue is performed to guide the surgeon in subsequent therapy. DESIGN: Practical experience in frozen section of the lung was reviewed in the medical literature and from the records of several academic hospitals. RESULTS: Most frozen sections of the lung are performed for evaluation of a solitary nodule, a mass, or the surgical margins of a resection. Frozen section may also be used to assess the adequacy of a lung wedge biopsy taken for later diagnosis of a condition. CONCLUSION: The pathologic evaluation of intraoperative pulmonary lesions is indicated for the differential diagnosis of pulmonary nodules and masses, both neoplastic and nonneoplastic, surgical resection margins, and mediastinal lymph nodes. The most worrisome pitfalls involve differentiating benign reactive atypia from malignancy on frozen section.
CONTEXT: Frozen section of lung tissue is performed to guide the surgeon in subsequent therapy. DESIGN: Practical experience in frozen section of the lung was reviewed in the medical literature and from the records of several academic hospitals. RESULTS: Most frozen sections of the lung are performed for evaluation of a solitary nodule, a mass, or the surgical margins of a resection. Frozen section may also be used to assess the adequacy of a lung wedge biopsy taken for later diagnosis of a condition. CONCLUSION: The pathologic evaluation of intraoperative pulmonary lesions is indicated for the differential diagnosis of pulmonary nodules and masses, both neoplastic and nonneoplastic, surgical resection margins, and mediastinal lymph nodes. The most worrisome pitfalls involve differentiating benign reactive atypia from malignancy on frozen section.
Authors: Gregory T Kennedy; Feredun S Azari; Elizabeth Bernstein; Charuhas Desphande; Azra Din; Isvita Marfatia; John C Kucharczuk; Edward J Delikatny; Philip S Low; Sunil Singhal Journal: Ann Thorac Surg Date: 2021-11-10 Impact factor: 5.102
Authors: Osnath Assayag; Martine Antoine; Brigitte Sigal-Zafrani; Michael Riben; Fabrice Harms; Adriano Burcheri; Kate Grieve; Eugénie Dalimier; Bertrand Le Conte de Poly; Claude Boccara Journal: Technol Cancer Res Treat Date: 2013-08-31
Authors: Laura M G van Huizen; Teodora Radonic; Frank van Mourik; Danielle Seinstra; Chris Dickhoff; Johannes M A Daniels; Idris Bahce; Jouke T Annema; Marie Louise Groot Journal: Transl Biophotonics Date: 2020-08-21