BACKGROUND: Cardiopulmonary resuscitation (CPR) was first introduced in 1960 for people who unexpectedly experience sudden cardiac arrest. Over the years, it became routine practice in all institutions to perform CPR for all patients even though, for some patients with fatal conditions, application of CPR only prolongs the dying process through temporarily restoring cardiac function. OBJECTIVES: This analysis aims to systematically review the literature to provide an accurate estimate of survival following CPR in patients with terminal health conditions. DATA SOURCES: A literature search was performed for studies published from January 1, 2004, until January 10, 2014. The search was updated monthly to March 1, 2014. REVIEW METHODS: Abstracts and full text of studies that met eligibility criteria were reviewed. Reference lists were also examined for any additional relevant studies not identified through the search. RESULTS: Cancer patients have lower survival rates following CPR than patients with conditions other than cancer, and cancer patients who receive CPR in intensive care units have one-fifth the rate of survival to discharge of cancer patients who receive CPR in general wards. While the meta-analysis of studies published between 1967 and 2005 reported a lower survival to discharge for cancer patients (6.2%), more recent studies reported higher survival to discharge or to 30-day survival for these patients. Higher survival rates in more recent studies could originate with more "do not attempt resuscitation" orders for patients with end-stage cancer in recent years. Older age does not significantly decrease the rate of survival following CPR while the degree, the type, and the number of chronic health conditions; functional dependence; and multiple CPRs (particularly in advanced age) do reduce survival rates. Emergency Medical Services response time have a significant impact on survival following out-of-hospital CPR. CONCLUSIONS: Survival after CPR depends on the severity of illness, type and number of health conditions, functional dependence, and multiple CPRs.
BACKGROUND: Cardiopulmonary resuscitation (CPR) was first introduced in 1960 for people who unexpectedly experience sudden cardiac arrest. Over the years, it became routine practice in all institutions to perform CPR for all patients even though, for some patients with fatal conditions, application of CPR only prolongs the dying process through temporarily restoring cardiac function. OBJECTIVES: This analysis aims to systematically review the literature to provide an accurate estimate of survival following CPR in patients with terminal health conditions. DATA SOURCES: A literature search was performed for studies published from January 1, 2004, until January 10, 2014. The search was updated monthly to March 1, 2014. REVIEW METHODS: Abstracts and full text of studies that met eligibility criteria were reviewed. Reference lists were also examined for any additional relevant studies not identified through the search. RESULTS:Cancerpatients have lower survival rates following CPR than patients with conditions other than cancer, and cancerpatients who receive CPR in intensive care units have one-fifth the rate of survival to discharge of cancerpatients who receive CPR in general wards. While the meta-analysis of studies published between 1967 and 2005 reported a lower survival to discharge for cancerpatients (6.2%), more recent studies reported higher survival to discharge or to 30-day survival for these patients. Higher survival rates in more recent studies could originate with more "do not attempt resuscitation" orders for patients with end-stage cancer in recent years. Older age does not significantly decrease the rate of survival following CPR while the degree, the type, and the number of chronic health conditions; functional dependence; and multiple CPRs (particularly in advanced age) do reduce survival rates. Emergency Medical Services response time have a significant impact on survival following out-of-hospital CPR. CONCLUSIONS: Survival after CPR depends on the severity of illness, type and number of health conditions, functional dependence, and multiple CPRs.
Authors: Gordon H Guyatt; Andrew D Oxman; Holger J Schünemann; Peter Tugwell; Andre Knottnerus Journal: J Clin Epidemiol Date: 2010-12-24 Impact factor: 6.437
Authors: Gary M Reisfield; Susannah Kish Wallace; Mark F Munsell; Fern J Webb; Edgar R Alvarez; George R Wilson Journal: Resuscitation Date: 2006-09-20 Impact factor: 5.262
Authors: William J Ehlenbach; Amber E Barnato; J Randall Curtis; William Kreuter; Thomas D Koepsell; Richard A Deyo; Renee D Stapleton Journal: N Engl J Med Date: 2009-07-02 Impact factor: 91.245
Authors: David J Pinato; Alberto Zambelli; Juan Aguilar-Company; Mark Bower; Christopher Sng; Ramon Salazar; Alexia Bertuzzi; Joan Brunet; Ricard Mesia; Elia Segui; Federica Biello; Daniele Generali; Salvatore Grisanti; Gianpiero Rizzo; Michela Libertini; Antonio Maconi; Nadia Harbeck; Bruno Vincenzi; Rossella Bertulli; Diego Ottaviani; Anna Carbo; Riccardo Bruna; Sarah Benafif; Andrea Marrari; Rachel Wuerstlein; M Carmen Carmona-Garcia; Neha Chopra; Carlo Tondini; Oriol Mirallas; Valeria Tovazzi; Marta Betti; Salvatore Provenzano; Vittoria Fotia; Claudia Andrea Cruz; Alessia Dalla Pria; Francesca D'Avanzo; Joanne S Evans; Nadia Saoudi-Gonzalez; Eudald Felip; Myria Galazi; Isabel Garcia-Fructuoso; Alvin J X Lee; Thomas Newsom-Davis; Andrea Patriarca; David Garcia-Illescas; Roxana Reyes; Palma Dileo; Rachel Sharkey; Yien Ning Sophia Wong; Daniela Ferrante; Javier Marco-Hernandez; Anna Sureda; Clara Maluquer; Isabel Ruiz-Camps; Gianluca Gaidano; Lorenza Rimassa; Lorenzo Chiudinelli; Macarena Izuzquiza; Alba Cabirta; Michela Franchi; Armando Santoro; Aleix Prat; Josep Tabernero; Alessandra Gennari Journal: Cancer Discov Date: 2020-07-31 Impact factor: 39.397