Literature DB >> 16384828

Predictors and outcome of cardiopulmonary resuscitation (CPR) calls in a large haemodialysis unit over a seven-year period.

Jean-Philippe Lafrance1, Linda Nolin, Lynne Senécal, Martine Leblanc.   

Abstract

BACKGROUND: Cardiac mortality is the leading cause of death in dialysis patients, with cardiac arrests being most frequent. Our purpose was to determine the epidemiology, predictors and outcomes of calls for cardiopulmonary resuscitation (CPR) occurring in our haemodialysis unit.
METHODS: We reviewed retrospectively all calls for CPR occurring in our unit between August 1997 and December 2004 and compared data to a cohort of chronic haemodialysis patients from our unit. Dialysis sessions performed in the ICUs were not included.
RESULTS: A total of 38 calls occurred over 307,553 sessions, corresponding to an incidence of 0.012%. In a multivariate logistic regression model, statistically significant predictors to have a call for CPR were ischaemic heart disease (OR: 3.93; 95% CI: 1.70-9.07), heart failure (OR: 2.74; 95% CI: 1.12-6.74) and female gender (OR: 2.96; 95% CI: 1.37-6.43). Patients who had a call for CPR had a lower dialysis vintage than control patients (OR: 0.98; 95% CI: 0.965-0.996). Twenty of the 38 events presented on Mondays or Tuesdays (P = 0.012); 78% occurred during haemodialysis, vs 14 and 8% immediately after and immediately before dialysis but still on the unit, respectively. Of the 38 events, 24 were true cardiopulmonary arrests. Cardiac etiology was the most frequent (34%) and only 4 events were attributed to potassium disorders. One quarter of patients were dialyzed against a dialysate potassium concentration of 1 mmol/l or below. An arrhythmia was identified in 19 patients; a malignant ventricular fibrillation or ventricular tachycardia was most frequently found (32%), followed by severe bradycardia (26%). For the whole group, there were 6 deaths (16%) within 48 h; 30 patients (79%) were alive at 30 days and discharged from the hospital. Among the 24 cardiopulmonary arrests, there were 4 deaths (17%) within 48 h; 18 patients (75%) were alive at 30 days and discharged from the hospital. There was a trend for worse prognosis at 60 days when related to cardiopulmonary etiology (P = 0.054) and when a true cardiopulmonary arrest occurred (P = 0.134).
CONCLUSIONS: This study confirms that arrest codes occur more frequently on Mondays and Tuesdays in a haemodialysis unit. Survival after an arrest code appears to be better than in certain other circumstances, probably in part because of the presence of witness, physician and equipment, and vascular access being readily available.

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Year:  2005        PMID: 16384828     DOI: 10.1093/ndt/gfk007

Source DB:  PubMed          Journal:  Nephrol Dial Transplant        ISSN: 0931-0509            Impact factor:   5.992


  24 in total

1.  Improving ascertainment of sudden cardiac death in patients with end stage renal disease.

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2.  Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma.

Authors:  Nadia A Atai; Manju Bansal; Cheungh Lo; Joost Bosman; Wikky Tigchelaar; Klazien S Bosch; Ard Jonker; Philip C De Witt Hamer; Dirk Troost; Christopher A McCulloch; Vincent Everts; Cornelis J F Van Noorden; Jaro Sodek
Journal:  Immunology       Date:  2010-08-17       Impact factor: 7.397

3.  Health Care for People Approaching the End of Life: An Evidentiary Framework.

Authors:  N Sikich; S Baidobonsoo; V Costa; C Hulobowich; K Kaulback; I Nevis; S Sehatzadeh; N Sikich; L Levin; B Pham; M Krahn
Journal:  Ont Health Technol Assess Ser       Date:  2014-12-01

4.  Outcomes of In-Hospital Cardiopulmonary Resuscitation in Maintenance Dialysis Patients.

Authors:  Fahad Saeed; Malik M Adil; Ahmed A Malik; Jesse D Schold; Jean L Holley
Journal:  J Am Soc Nephrol       Date:  2015-04-23       Impact factor: 10.121

5.  Cardiopulmonary Resuscitation in Outpatient Dialysis Clinics: Perception of Futility?

Authors:  Benoit Imbeault; Christopher T Chan
Journal:  J Am Soc Nephrol       Date:  2019-02-07       Impact factor: 10.121

6.  Primary prevention implantable cardioverter defibrillators in end-stage kidney disease patients on dialysis: a matched cohort study.

Authors:  Patrick H Pun; Anne S Hellkamp; Gillian D Sanders; John P Middleton; Stephen C Hammill; Hussein R Al-Khalidi; Lesley H Curtis; Gregg C Fonarow; Sana M Al-Khatib
Journal:  Nephrol Dial Transplant       Date:  2014-11-17       Impact factor: 5.992

7.  In-Hospital Cardiac Arrest Resuscitation Practices and Outcomes in Maintenance Dialysis Patients.

Authors:  Monique Anderson Starks; Jingjing Wu; Eric D Peterson; Judith A Stafford; Roland A Matsouaka; L Ebony Boulware; Laura P Svetkey; Paul S Chan; Patrick H Pun
Journal:  Clin J Am Soc Nephrol       Date:  2020-01-07       Impact factor: 8.237

8.  End-of-life care preferences and needs: perceptions of patients with chronic kidney disease.

Authors:  Sara N Davison
Journal:  Clin J Am Soc Nephrol       Date:  2010-01-14       Impact factor: 8.237

Review 9.  Cardiopulmonary Resuscitation in Patients With Terminal Illness: An Evidence-Based Analysis.

Authors:  S Sehatzadeh
Journal:  Ont Health Technol Assess Ser       Date:  2014-12-01

10.  The association of ECG and echocardiographic abnormalities with sudden cardiac death in a dialysis patient cohort.

Authors:  Darren Green; James P Ritchie; Nik Abidin; David I New; Philip A Kalra
Journal:  J Nephrol       Date:  2013-12-12       Impact factor: 3.902

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