Ruth E Hubbard1, Nancye M Peel1, Morgan Smith2,3, Blake Dawson3, Zahed Lambat3, Melissa Bak3, Jennifer Best4, David W Johnson4. 1. Centre for Research in Geriatric Medicine, The University of Queensland, Brisbane, Queensland, Australia. 2. Ochsner Medical School, New Orleans, Louisiana, USA. 3. School of Medicine, The University of Queensland, Brisbane, Queensland, Australia. 4. Department of Nephrology, The University of Queensland, Brisbane, Queensland, Australia.
Abstract
AIM: To determine whether the frailty status of patients with chronic kidney disease (CKD) can be measured using a Frailty index (FI). METHODS: One hundred and eleven attending a nephrology clinic were approached to complete a one-page questionnaire evaluating cognitive, psychological and functional status. Data were coded as deficits, summed and divided by the total number of deficits considered, to derive an FI-CKD. RESULTS: One hundred and ten (mean age 65.2 years) agreed to participate and assessments took approximately 10 minutes to complete. Mean FI-CKD was 0.25 (SD 0.12). The FI-CKD increased with age at 3% per year, correlated with a modified Fried phenotype (P < 0.001) and increased significantly across CKD stages (P = 0.04). CONCLUSIONS: The FI-CKD is feasible in the outpatient setting and has good construct validity. The greater granularity of a continuous measure has the potential to inform decision-making regarding appropriate interventions for patients at the 'frail' end of the health spectrum.
AIM: To determine whether the frailty status of patients with chronic kidney disease (CKD) can be measured using a Frailty index (FI). METHODS: One hundred and eleven attending a nephrology clinic were approached to complete a one-page questionnaire evaluating cognitive, psychological and functional status. Data were coded as deficits, summed and divided by the total number of deficits considered, to derive an FI-CKD. RESULTS: One hundred and ten (mean age 65.2 years) agreed to participate and assessments took approximately 10 minutes to complete. Mean FI-CKD was 0.25 (SD 0.12). The FI-CKD increased with age at 3% per year, correlated with a modified Fried phenotype (P < 0.001) and increased significantly across CKD stages (P = 0.04). CONCLUSIONS: The FI-CKD is feasible in the outpatient setting and has good construct validity. The greater granularity of a continuous measure has the potential to inform decision-making regarding appropriate interventions for patients at the 'frail' end of the health spectrum.
Authors: Jeremy Walston; Thomas N Robinson; Susan Zieman; Frances McFarland; Christopher R Carpenter; Keri N Althoff; Melissa K Andrew; Caroline S Blaum; Patrick J Brown; Brian Buta; E Wesley Ely; Luigi Ferrucci; Kevin P High; Stephen B Kritchevsky; Kenneth Rockwood; Kenneth E Schmader; Felipe Sierra; Kaycee M Sink; Ravi Varadhan; Arti Hurria Journal: J Am Geriatr Soc Date: 2017-04-19 Impact factor: 5.562
Authors: Alexandra Legge; Susan Kirkland; Kenneth Rockwood; Pantelis Andreou; Sang-Cheol Bae; Caroline Gordon; Juanita Romero-Diaz; Jorge Sanchez-Guerrero; Daniel J Wallace; Sasha Bernatsky; Ann E Clarke; Joan T Merrill; Ellen M Ginzler; Paul Fortin; Dafna D Gladman; Murray B Urowitz; Ian N Bruce; David A Isenberg; Anisur Rahman; Graciela S Alarcón; Michelle Petri; Munther A Khamashta; M A Dooley; Rosalind Ramsey-Goldman; Susan Manzi; Kristjan Steinsson; Asad A Zoma; Cynthia Aranow; Meggan Mackay; Guillermo Ruiz-Irastorza; S Sam Lim; Murat Inanc; Ronald F van Vollenhoven; Andreas Jonsen; Ola Nived; Manuel Ramos-Casals; Diane L Kamen; Kenneth C Kalunian; Soren Jacobsen; Christine A Peschken; Anca Askanase; John G Hanly Journal: Arthritis Rheumatol Date: 2019-05-29 Impact factor: 10.995
Authors: Alexandra Legge; Susan Kirkland; Kenneth Rockwood; Pantelis Andreou; Sang-Cheol Bae; Caroline Gordon; Juanita Romero-Diaz; Jorge Sanchez-Guerrero; Daniel J Wallace; Sasha Bernatsky; Ann E Clarke; Joan T Merrill; Ellen M Ginzler; Paul Fortin; Dafna D Gladman; Murray B Urowitz; Ian N Bruce; David A Isenberg; Anisur Rahman; Graciela S Alarcón; Michelle Petri; Munther A Khamashta; M A Dooley; Rosalind Ramsey-Goldman; Susan Manzi; Asad A Zoma; Cynthia Aranow; Meggan Mackay; Guillermo Ruiz-Irastorza; S Sam Lim; Murat Inanc; Ronald F van Vollenhoven; Andreas Jonsen; Ola Nived; Manuel Ramos-Casals; Diane L Kamen; Kenneth C Kalunian; Soren Jacobsen; Christine A Peschken; Anca Askanase; John G Hanly Journal: J Rheumatol Date: 2019-04-15 Impact factor: 4.666
Authors: Rasheeda K Hall; Sarah Morton; Jonathan Wilson; Dae Hyun Kim; Cathleen Colón-Emeric; Julia J Scialla; Alyssa Platt; Patti L Ephraim; L Ebony Boulware; Jane Pendergast Journal: Kidney360 Date: 2022-07-19
Authors: David A Clark; Usman Khan; Bryce A Kiberd; Colin C Turner; Alison Dixon; David Landry; Heather C Moffatt; Paige A Moorhouse; Karthik K Tennankore Journal: BMC Nephrol Date: 2017-05-02 Impact factor: 2.388
Authors: Anna Torné; Emma Puigoriol; Edurne Zabaleta-Del-Olmo; Juan-José Zamora-Sánchez; Sebastià Santaeugènia; Jordi Amblàs-Novellas Journal: Int J Environ Res Public Health Date: 2021-05-13 Impact factor: 3.390