Literature DB >> 26332823

Photocatalytic Radical Trifluoromethylation/Cyclization Cascade: Synthesis of CF3-Containing Pyrazolines and Isoxazolines.

Qiang Wei1, Jia-Rong Chen1, Xiao-Qiang Hu1, Xiao-Chen Yang1, Bin Lu1, Wen-Jing Xiao1.   

Abstract

A general visible light induced photoredox-catalyzed radical trifluoromethylation/cyclization cascade of β-aryl-β,γ-unsaturated hydrazones and oximes is described. The protocol enables an efficient access to various densely functionalized and biologically important CF3-containing dihydropyrazoles and isoxazolines with generally high yields.

Entities:  

Year:  2015        PMID： 26332823     DOI： 10.1021/acs.orglett.5b02118

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  8 in total

1.  Brønsted acid-promoted hydroamination of unsaturated hydrazones: access to biologically important 5-arylpyrazolines.

Authors:  Han He; Ning Xu; Honglin Zhang; Bin Chen; Zhengnan Hu; Kang Guo; Jianlin Chun; Shujun Cao; Yingguang Zhu
Journal:  RSC Adv       Date:  2021-05-11       Impact factor: 4.036

2.  Hypervalent iodine-mediated Ritter-type amidation of terminal alkenes: The synthesis of isoxazoline and pyrazoline cores.

Authors:  Sang Won Park; Soong-Hyun Kim; Jaeyoung Song; Ga Young Park; Darong Kim; Tae-Gyu Nam; Ki Bum Hong
Journal:  Beilstein J Org Chem       Date:  2018-05-11       Impact factor: 2.883

3.  Metal-free alkene oxy- and amino-perfluoroalkylations via carbocation formation by using perfluoro acid anhydrides: unique reactivity between styrenes and perfluoro diacyl peroxides.

Authors:  Elena Valverde; Shintaro Kawamura; Daisuke Sekine; Mikiko Sodeoka
Journal:  Chem Sci       Date:  2018-08-01       Impact factor: 9.825

4.  Enantioselective 5-exo-Fluorocyclization of Ene-Oximes.

Authors:  Taiki Rouno; Tomoki Niwa; Kousuke Nishibashi; Nobuharu Yamamoto; Hiromichi Egami; Yoshitaka Hamashima
Journal:  Molecules       Date:  2019-09-24       Impact factor: 4.411

Review 5.  Oxime radicals: generation, properties and application in organic synthesis.

Authors:  Igor B Krylov; Stanislav A Paveliev; Alexander S Budnikov; Alexander O Terent'ev
Journal:  Beilstein J Org Chem       Date:  2020-06-05       Impact factor: 2.883

6.  Formal [4 + 1] cycloaddition of in situ generated 1,2-diaza-1,3-dienes with diazo esters: facile approaches to dihydropyrazoles containing a quaternary center.

Authors:  Bo Chen; Wen-Dao Chu; Quan-Zhong Liu
Journal:  RSC Adv       Date:  2019-01-11       Impact factor: 4.036

7.  Photocatalytic cyclization of nitrogen-centered radicals with carbon nitride through promoting substrate/catalyst interaction.

Authors:  Mingcheng Yang; Ronghong Lian; Xirui Zhang; Chong Wang; Jiajia Cheng; Xinchen Wang
Journal:  Nat Commun       Date:  2022-08-20       Impact factor: 17.694

8.  Visible-light-induced oxidant and metal-free dehydrogenative cascade trifluoromethylation and oxidation of 1,6-enynes with water.

Authors:  Sadhan Jana; Ajay Verma; Rahul Kadu; Sangit Kumar
Journal:  Chem Sci       Date:  2017-07-10       Impact factor: 9.825
  8 in total

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