OBJECTIVE: This study was conducted to research the factors determining biochemical recurrence (BCR) in low-risk localized prostate cancer patients who underwent radical prostatectomy (RP). MATERIALS AND METHODS: We retrospectively analyzed the data of 504 patients who had undergone RP between 2003 and 2013 at our clinic. One hundred and fifty-two patients who underwent RP for low-risk prostate cancer were included in the study. RESULTS: The mean follow-up period for patients was 58.7 (21-229) months. The mean age of the patients was 63.7±7.2 years (49-79). The mean prostate specific antigen (PSA) value was 5.25±4.22 ng/mL (3.58-9.45). The BCR rate after the operation was 25% (38/152). In the univariate analysis, recurrence determining factors were shown to include extracapsular involvement (ECI) (p=0.004), capsular invasion (CI) (p=0.001), age (p=0.014), and tumor size (p=0.006). However, only CI was found to be significant in multivariate analysis (p=0.001). CONCLUSION: Capsular invasion is an independent risk factor in low-risk prostate cancer patients who underwent RP for BCR.
OBJECTIVE: This study was conducted to research the factors determining biochemical recurrence (BCR) in low-risk localized prostate cancerpatients who underwent radical prostatectomy (RP). MATERIALS AND METHODS: We retrospectively analyzed the data of 504 patients who had undergone RP between 2003 and 2013 at our clinic. One hundred and fifty-two patients who underwent RP for low-risk prostate cancer were included in the study. RESULTS: The mean follow-up period for patients was 58.7 (21-229) months. The mean age of the patients was 63.7±7.2 years (49-79). The mean prostate specific antigen (PSA) value was 5.25±4.22 ng/mL (3.58-9.45). The BCR rate after the operation was 25% (38/152). In the univariate analysis, recurrence determining factors were shown to include extracapsular involvement (ECI) (p=0.004), capsular invasion (CI) (p=0.001), age (p=0.014), and tumor size (p=0.006). However, only CI was found to be significant in multivariate analysis (p=0.001). CONCLUSION: Capsular invasion is an independent risk factor in low-risk prostate cancerpatients who underwent RP for BCR.
Authors: D G Bostwick; D J Grignon; M E Hammond; M B Amin; M Cohen; D Crawford; M Gospadarowicz; R S Kaplan; D S Miller; R Montironi; T F Pajak; A Pollack; J R Srigley; J W Yarbro Journal: Arch Pathol Lab Med Date: 2000-07 Impact factor: 5.534
Authors: Lars Budäus; Hendrik Isbarn; Christian Eichelberg; Giovanni Lughezzani; Maxine Sun; Paul Perrotte; Felix K H Chun; Georg Salomon; Thomas Steuber; Jens Köllermann; Guido Sauter; Sascha A Ahyai; Mario Zacharias; Margit Fisch; Thorsten Schlomm; Alexander Haese; Hans Heinzer; Hartwig Huland; Francesco Montorsi; Markus Graefen; Pierre I Karakiewicz Journal: J Urol Date: 2010-08-17 Impact factor: 7.450
Authors: Anthony V D'Amico; Richard Whittington; S Bruce Malkowicz; Kerri Cote; Marian Loffredo; Delray Schultz; Ming-Hui Chen; John E Tomaszewski; Andrew A Renshaw; Alan Wein; Jerome P Richie Journal: Cancer Date: 2002-07-15 Impact factor: 6.860
Authors: Michael Aleman; Pierre I Karakiewicz; Patrick Kupelian; Michael W Kattan; Markus Graefen; Ilias Cagiannos; James Eastham; Peter T Scardino; Hartwig Huland; Eric A Klein Journal: Urology Date: 2003-07 Impact factor: 2.649
Authors: Jun Taik Lee; Seungsoo Lee; Chang Jin Yun; Byung Joo Jeon; Jung Man Kim; Hong Koo Ha; Wan Lee; Moon Kee Chung Journal: Korean J Urol Date: 2010-11-17
Authors: Laurent Salomon; Aristotelis G Anastasiadis; Christopher W Johnson; James M McKiernan; Erik T Goluboff; Claude C Abbou; Carl A Olsson; Mitchell C Benson Journal: Urology Date: 2003-08 Impact factor: 2.649
Authors: Kevin Martell; Soumyajit Roy; Tyler Meyer; Jordan Stosky; Will Jiang; Kundan Thind; Michael Roumeliotis; John Bosch; Steve Angyalfi; Harvey Quon; Siraj Husain Journal: Heliyon Date: 2020-06-07