Literature DB >> 26324280

Whole-genome sequencing identifies emergence of a quinolone resistance mutation in a case of Stenotrophomonas maltophilia bacteremia.

Theodore R Pak1, Deena R Altman2, Oliver Attie1, Robert Sebra1, Camille L Hamula3, Martha Lewis1, Gintaras Deikus1, Leah C Newman1, Gang Fang1, Jonathan Hand2, Gopi Patel2, Fran Wallach2, Eric E Schadt1, Shirish Huprikar2, Harm van Bakel1, Andrew Kasarskis4, Ali Bashir1.   

Abstract

Whole-genome sequences for Stenotrophomonas maltophilia serial isolates from a bacteremic patient before and after development of levofloxacin resistance were assembled de novo and differed by one single-nucleotide variant in smeT, a repressor for multidrug efflux operon smeDEF. Along with sequenced isolates from five contemporaneous cases, they displayed considerable diversity compared against all published complete genomes. Whole-genome sequencing and complete assembly can conclusively identify resistance mechanisms emerging in S. maltophilia strains during clinical therapy.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26324280      PMCID： PMC4604410          DOI： 10.1128/AAC.01723-15

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

1.  Expression of multidrug efflux pump SmeDEF by clinical isolates of Stenotrophomonas maltophilia.

Authors:  A Alonso; J L Martinez
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

2.  Mauve: multiple alignment of conserved genomic sequence with rearrangements.

Authors:  Aaron C E Darling; Bob Mau; Frederick R Blattner; Nicole T Perna
Journal:  Genome Res       Date:  2004-07       Impact factor: 9.043

3.  Structural and functional analysis of SmeT, the repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF.

Authors:  Alvaro Hernández; María J Maté; Patricia C Sánchez-Díaz; Antonio Romero; Fernando Rojo; José L Martínez
Journal:  J Biol Chem       Date:  2009-03-26       Impact factor: 5.157

4.  Using MUMmer to identify similar regions in large sequence sets.

Authors:  Arthur L Delcher; Steven L Salzberg; Adam M Phillippy
Journal:  Curr Protoc Bioinformatics       Date:  2003-02

5.  Multiple antibiotic resistance in Stenotrophomonas maltophilia.

Authors:  A Alonso; J L Martínez
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191

6.  Preservation of topoisomerase genetic sequences during in vivo and in vitro development of high-level resistance to ciprofloxacin in isogenic Stenotrophomonas maltophilia strains.

Authors:  Sylvia Valdezate; Ana Vindel; Juan Antonio Saéz-Nieto; Fernando Baquero; Rafael Cantón
Journal:  J Antimicrob Chemother       Date:  2005-05-31       Impact factor: 5.790

7.  Cloning and characterization of SmeT, a repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF.

Authors:  Patricia Sánchez; Ana Alonso; Jose L Martinez
Journal:  Antimicrob Agents Chemother       Date:  2002-11       Impact factor: 5.191

8.  Topoisomerase II and IV quinolone resistance-determining regions in Stenotrophomonas maltophilia clinical isolates with different levels of quinolone susceptibility.

Authors:  Sylvia Valdezate; Ana Vindel; Aurora Echeita; Fernando Baquero; Rafael Cantó
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

9.  Stenotrophomonas maltophilia: emergence of multidrug-resistant strains during therapy and in an in vitro pharmacodynamic chamber model.

Authors:  M W Garrison; D E Anderson; D M Campbell; K C Carroll; C L Malone; J D Anderson; R J Hollis; M A Pfaller
Journal:  Antimicrob Agents Chemother       Date:  1996-12       Impact factor: 5.191

10.  The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants.

Authors:  Lisa C Crossman; Virginia C Gould; J Maxwell Dow; Georgios S Vernikos; Aki Okazaki; Mohammed Sebaihia; David Saunders; Claire Arrowsmith; Tim Carver; Nicholas Peters; Ellen Adlem; Arnaud Kerhornou; Angela Lord; Lee Murphy; Katharine Seeger; Robert Squares; Simon Rutter; Michael A Quail; Mari-Adele Rajandream; David Harris; Carol Churcher; Stephen D Bentley; Julian Parkhill; Nicholas R Thomson; Matthew B Avison
Journal:  Genome Biol       Date:  2008-04-17       Impact factor: 13.583
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  8 in total

1.  Novel Mechanisms of Efflux-Mediated Levofloxacin Resistance and Reduced Amikacin Susceptibility in Stenotrophomonas maltophilia.

Authors:  Punyawee Dulyayangkul; Karina Calvopiña; Kate J Heesom; Matthew B Avison
Journal:  Antimicrob Agents Chemother       Date:  2020-12-16       Impact factor: 5.191

2.  Stenotrophomonas maltophilia produces an EntC-dependent catecholate siderophore that is distinct from enterobactin.

Authors:  Megan Y Nas; Nicholas P Cianciotto
Journal:  Microbiology       Date:  2017-10-06       Impact factor: 2.777

3.  Identification and analysis of seven effector protein families with different adaptive and evolutionary histories in plant-associated members of the Xanthomonadaceae.

Authors:  Renata de A B Assis; Lorraine Cristina Polloni; José S L Patané; Shalabh Thakur; Érica B Felestrino; Julio Diaz-Caballero; Luciano Antonio Digiampietri; Luiz Ricardo Goulart; Nalvo F Almeida; Rafael Nascimento; Abhaya M Dandekar; Paulo A Zaini; João C Setubal; David S Guttman; Leandro Marcio Moreira
Journal:  Sci Rep       Date:  2017-11-23       Impact factor: 4.379

4.  Heterogeneous Colistin-Resistance Phenotypes Coexisting in Stenotrophomonas maltophilia Isolates Influence Colistin Susceptibility Testing.

Authors:  Sònia Martínez-Servat; Daniel Yero; Pol Huedo; Roser Marquez; Gara Molina; Xavier Daura; Isidre Gibert
Journal:  Front Microbiol       Date:  2018-11-22       Impact factor: 5.640

5.  Advances in the Microbiology of Stenotrophomonas maltophilia.

Authors:  Joanna S Brooke
Journal:  Clin Microbiol Rev       Date:  2021-05-26       Impact factor: 50.129

6.  GET_PHYLOMARKERS, a Software Package to Select Optimal Orthologous Clusters for Phylogenomics and Inferring Pan-Genome Phylogenies, Used for a Critical Geno-Taxonomic Revision of the Genus Stenotrophomonas.

Authors:  Pablo Vinuesa; Luz E Ochoa-Sánchez; Bruno Contreras-Moreira
Journal:  Front Microbiol       Date:  2018-05-01       Impact factor: 5.640

7.  Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing.

Authors:  Shijia Zhu; John Beaulaurier; Gintaras Deikus; Tao P Wu; Maya Strahl; Ziyang Hao; Guanzheng Luo; James A Gregory; Andrew Chess; Chuan He; Andrew Xiao; Robert Sebra; Eric E Schadt; Gang Fang
Journal:  Genome Res       Date:  2018-05-15       Impact factor: 9.438

8.  Common Adaptive Strategies Underlie Within-Host Evolution of Bacterial Pathogens.

Authors:  Yair E Gatt; Hanah Margalit
Journal:  Mol Biol Evol       Date:  2021-03-09       Impact factor: 16.240
  8 in total

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