Literature DB >> 26321602

The discovery of Arylex™ active and Rinskor™ active: Two novel auxin herbicides.

Jeffrey B Epp1, Anita L Alexander2, Terry W Balko2, Ann M Buysse2, William K Brewster2, Kristy Bryan2, John F Daeuble2, Stephen C Fields2, Roger E Gast2, Renard A Green2, Nicholas M Irvine2, William C Lo2, Christian T Lowe2, James M Renga2, John S Richburg2, James M Ruiz2, Norbert M Satchivi2, Paul R Schmitzer2, Thomas L Siddall2, Jeffery D Webster2, Monte R Weimer2, Gregory T Whiteker2, Carla N Yerkes2.   

Abstract

Multiple classes of commercially important auxin herbicides have been discovered since the 1940s including the aryloxyacetates (2,4-D, MCPA, dichlorprop, mecoprop, triclopyr, and fluroxypyr), the benzoates (dicamba), the quinoline-2-carboxylates (quinclorac and quinmerac), the pyrimidine-4-carboxylates (aminocyclopyrachlor), and the pyridine-2-carboxylates (picloram, clopyralid, and aminopyralid). In the last 10 years, two novel pyridine-2-carboxylate (or picolinate) herbicides were discovered at Dow AgroSciences. This paper will describe the structure activity relationship study that led to the discovery of the 6-aryl-picolinate herbicides Arylex™ active (2005) and Rinskor™ active (2010). While Arylex was developed primarily for use in cereal crops and Rinskor is still in development primarily for use in rice crops, both herbicides will also be utilized in additional crops.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  6-Aryl-picolinate; Arylex; Halauxifen; Halauxifen-methyl; Picolinate; Rinskor

Mesh:

Substances:

Year:  2015        PMID: 26321602     DOI: 10.1016/j.bmc.2015.08.011

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


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